Assessment of subjective health and health-related quality of life in persons with acquired or degenerative brain injury.

abstract：:An increasing number of mutations in the CACNA1A gene have been identified, which are associated with a broad clinical spectrum, including familial hemiplegic migraine. Transfection studies and mouse model analyses are currently being undertaken to study the correlation between CACNA1A mutations and disease. ...

journal_title：Current opinion in neurology

authors： Kors EE,van den Maagdenberg AM,Plomp JJ,Frants RR,Ferrari MD

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The diagnosis of amyotrophic lateral sclerosis (ALS) still relies mainly on clinical criteria. In present review we will provide an overview of neurochemical ALS biomarkers, which are in the most advanced position on the way towards inclusion into the clinical work-up. RECENT FINDINGS:The field of AL...

journal_title：Current opinion in neurology

authors： Verde F,Silani V,Otto M

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the currently known side effects of the approved therapies of multiple sclerosis and to suggest monitoring procedures. RECENT FINDINGS:The progress in the treatment of multiple sclerosis with new very effective therapies is accompanied by a number of side effects. Some of these have alre...

journal_title：Current opinion in neurology

authors： Moiola L,Rommer PS,Zettl UK

更新日期：2020-06-01 00:00:00

abstract：:This is a review of chemotherapy options for patients with brain tumors, both at the time of initial diagnosis and at recurrence. Gliomas, the most common malignant brain tumors, represent the main focus of the review; chemotherapeutic options for supratentorial, brain stem, and optic track gliomas are discussed. ...

journal_title：Current opinion in neurology

authors： Galanis E,Buckner JC

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent progress in serological screening for paraneoplastic autoantibodies and diagnostic imaging techniques to detect malignancies has resulted in a broadening of the concept of paraneoplastic neurologic syndromes through the characterization of nonclassical clinical features. The goal of this articl...

journal_title：Current opinion in neurology

authors： Koike H,Tanaka F,Sobue G

更新日期：2011-10-01 00:00:00

abstract：:A long series of studies beginning with the pioneering experiments of Wiesel and Hubel [1] has shown that correct visual experience is crucial for the development of the visual system. Recent results suggest that neurotrophic factors of the nerve growth factor family might have a relevant role in mediating the effects...

journal_title：Current opinion in neurology

authors： Pizzorusso T,Maffei L

更新日期：1996-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To give an overview of recent data on the use of skin biopsy as a diagnostic tool in neuropathies. RECENT FINDINGS:The sensitivity and specificity of skin biopsy in detecting small fiber neuropathy is supported by new data. In many patients with small fiber neuropathy, a treatable disorder can be ide...

journal_title：Current opinion in neurology

authors： Sommer C

更新日期：2008-10-01 00:00:00

abstract：:Ablative surgery and deep brain stimulation for Parkinson's disease can be performed in the thalamus, the pallidum and the subthalamic nucleus. The efficacy and safety of unilateral pallidotomy is well established. Deep brain stimulation has a lower morbidity and is preferred for bilateral surgery. The subthalamic nuc...

journal_title：Current opinion in neurology

authors： Krack P,Hamel W,Mehdorn HM,Deuschl G

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Cognitive impairments are common in children with epilepsy. They may already be present before the onset of epilepsy or occur - and even progress - during its course. Many variables contribute to cognitive dysfunction. Those that can be targeted to prevent (further) cognitive impairment will be highli...

journal_title：Current opinion in neurology

authors： Braun KP

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The demyelinating disease multiple sclerosis has an autoimmune inflammatory component, which has dominated the description of multiple sclerosis. A degenerative component to multiple sclerosis was always apparent, but was underappreciated until recently. Recent work has brought axonal pathology and br...

journal_title：Current opinion in neurology

authors： Owens T

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Tension-type headache is the most common type of headache and, in its chronic form, one of the most neglected and difficult types of headache to treat. Recently published data will be reviewed. RECENT FINDINGS:The prevalence of frequent tension-type headache increased significantly from 1989 to 2001,...

journal_title：Current opinion in neurology

authors： Bendtsen L,Jensen R

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the recent studies assessing patients with psychogenic nonepileptic seizures and developments in treatment. RECENT FINDINGS:The misdiagnosis of nonepileptic seizure is costly to patients, the healthcare system, and to society. Patients with nonepileptic seizures are prescribed ...

journal_title：Current opinion in neurology

authors： LaFrance WC Jr

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:New insights into the psychophysiological determinants of performance changes and brain plasticity associated with motor sequence learning have recently been gained through behavioral and imaging studies in healthy individuals. In addition, using a variety of motor sequential paradigms in groups of pa...

journal_title：Current opinion in neurology

authors： Doyon J

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Precise localization of the epileptogenic zone is imperative for the success of resective surgery of drug-resistant epileptic patients. To decrease the number of surgical failures, clinical research has been focusing on finding new biomarkers. For the past decades, high-frequency oscillations (HFOs, 8...

journal_title：Current opinion in neurology

authors： Roehri N,Bartolomei F

更新日期：2019-04-01 00:00:00

abstract：:Recent advances in clinical neurophysiology of epilepsy have enhanced our ability to study the epileptogenic region and have improved the localization of seizures in patients with intractable epilepsy. Computed spike analyses using electroencephalogram or magnetoencephalography superimposed on magnetic resonance image...

journal_title：Current opinion in neurology

authors： Masuoka LK,Spencer SS

更新日期：1994-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Longitudinal studies that use MRI scans performed over multiple time-points have been increasingly employed in the study of different neurological disorders, including degenerative dementia, multiple sclerosis, and epilepsy. RECENT FINDINGS:Although it is well established that increased rates of brai...

journal_title：Current opinion in neurology

authors： Whitwell JL

更新日期：2008-08-01 00:00:00

abstract：:Trauma to the developing brain constitutes an unexplored field. The few studies attempting to model and study paediatric head trauma, the leading cause of death and disability in the paediatric population, have revealed interesting aspects and potential targets for future research. One feature unique to the developing...

journal_title：Current opinion in neurology

authors： Felderhoff-Mueser U,Ikonomidou C

更新日期：2000-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Research on the pathophysiology of syndromic autism spectrum disorder (ASD) has contributed to the uncovering of mechanisms in nonsyndromic ASD. The current review aims to compare recent progress in therapeutics development for ASD with those for fragile X syndrome (FXS), the most frequent monogenic f...

journal_title：Current opinion in neurology

authors： Yamasue H,Aran A,Berry-Kravis E

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Parkinson's disease is the second most common neurodegenerative disorder and affects 2% of the population over the age of 60 years. Due to the increasing proportion of elderly individuals in developed countries, Parkinson's disease and related neurodegenerative disorders represent a growing burden on ...

journal_title：Current opinion in neurology

authors： Gasser T

更新日期：2005-08-01 00:00:00

abstract：:The motoneuron has a strong ability to regenerate after injury. However, the problems of nerve cell survival after a proximal axotomy, difficulty in axonal elongation after intraspinal lesion and the lack of target specificity during nerve fibre regrowth interfere with a good functional restitution. Current research h...

journal_title：Current opinion in neurology

authors： Carlstedt T

更新日期：2000-12-01 00:00:00

abstract：:New functional imaging techniques, including positron emission tomography, transcranial magnetic stimulation and functional magnetic resonance imaging, promise to allow the noninvasive study of haemodynamic, metabolic and activation parameters during acute migraine attacks in humans. These techniques are currently bei...

journal_title：Current opinion in neurology

authors： Cutrer FM,O'Donnell A

更新日期：1999-06-01 00:00:00

abstract：:Neuropharmacology is aiding our understanding of the control of eye movements in at least three ways. First, neurotransmitters have been identified in the pathways that coordinate gaze. Second, the technique of pharmacologic inactivation has provided a powerful method to determine the contributions of populations of n...

journal_title：Current opinion in neurology

authors： Leigh RJ,Ramat S

更新日期：1999-02-01 00:00:00

abstract：:The review intends to draw the attention of researchers working in retinal degenerations on the fact that classical apoptosis, for example, apoptosis triggering caspase activation, may not be the main pathway of cellular demise in this tissue.Former work already showed the difficulty of proving the activation of apopt...

journal_title：Current opinion in neurology

authors： Torriglia A,Jaadane I,Lebon C

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on our knowledge regarding prevention and management of medication overuse headache (MOH). RECENT FINDINGS:The prevalence of MOH is 1-2% in the general population worldwide, and because of the tremendous socio-economic cost, it is likely to be the most costly neurologic...

journal_title：Current opinion in neurology

authors： Russell MB,Lundqvist C

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the applicability of a framework of frontal lobe functioning to understand the sequelae of traumatic brain injury (TBI). RECENT FINDINGS:TBI research illustrates the need for improved phenotyping of TBI outcome. The functions of the frontal lobes are divisible into four distinct ...

journal_title：Current opinion in neurology

authors： Stuss DT

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Myasthenic syndromes are distinct disorders at the neuromuscular junction, most often with well characterized autoimmune or genetic pathology. New aspects of the dysfunctions give insight into the normal neuromuscular function in addition to giving therapeutic clues and tailoring the therapy to the pa...

journal_title：Current opinion in neurology

authors： Gilhus NE

更新日期：2012-10-01 00:00:00

abstract：:A relatively small number of studies were published on the intra-arterial therapy of stroke in the past year. Those reports, however, do offer strong evidence for the feasibility and safety of this therapeutic approach. Partly on the basis of these data it has become evident that the intra-arterial thrombolytic therap...

journal_title：Current opinion in neurology

authors： Abou-Chebl A,Furlan AJ

更新日期：2000-02-01 00:00:00

abstract：:Desmin-related myopathies are marked by accumulation of desmin, which is often familial and associated with cardiomyopathy. When multifocal this excess is characterized by inclusions such as cytoplasmic or spheroid bodies, when disseminated the excess is called granulofilamentous material. Excess of desmin might repre...

journal_title：Current opinion in neurology

authors： Goebel HH

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The computational power of the brain arises from the complex interactions between neurons. One straightforward method to quantify the strength of neuronal interactions is by measuring correlation and coherence. Efforts to measure correlation have been advancing rapidly of late, spurred by the developm...

journal_title：Current opinion in neurology

authors： Snyder AC,Smith MA

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The cause of multiple sclerosis remains elusive. We review recent epidemiological studies of genetic and environmental factors that influence susceptibility to the disease and its clinical course. RECENT FINDINGS:Genetic advances strengthen the association of multiple sclerosis with the human leukocy...

journal_title：Current opinion in neurology

authors： Kantarci O,Wingerchuk D

更新日期：2006-06-01 00:00:00