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Spinal cord metastasis of a non-neurofibromatosis type-1 malignant peripheral nerve sheath tumor: an unusual manifestation of a rare tumor.

Abstract：

:Malignant peripheral nerve sheath tumors are rare spindle-cell sarcomas derived from Schwann cells or pluripotent cells of the neural crest. They arise from the spinal roots, peripheral nerves, brachial and lumbosacral plexi, cranial nerves and terminal nerve fibers within soft tissue, intestine, lung and bone. These tumors recur either locally, or metastasize distally. Most of these tumors occur in association with neurofibromatosis type 1. Spinal cord metastasis from malignant nerve sheath tumors associated with neurofibromatosis type 1 is very rare. We describe a rare case of near-total spinal cord metastasis in a patient with malignant nerve sheath tumor in the absence of neurofibromatosis, and highlight the microscopic findings and natural history of this disease process.

journal_name

J Neurooncol

journal_title

Journal of neuro-oncology

authors

Baek WS,Pytel P,Undevia SD,Rubeiz H

doi

10.1007/s11060-004-4596-4

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

183-5

issue

2

eissn

0167-594X

issn

1573-7373

journal_volume

74

pub_type

杂志文章

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