Fractal analysis of the laminar organization of spinal cord neurons.

Abstract:

:Images of Golgi impregnated neurons from different laminae of the human and rat dorsal horns were subjected to a quantitative analysis to support the Rexed's laminar scheme in mammals. Four methods of fractal analysis were performed in the proceedings: box-counting, mass-radius, cumulative intersection, and vectorized intersection. The results show that the box-counting method is more precise than the other fractal methods performed, and offers support for the conclusion that fractal analysis can successfully discriminate the neuron populations among different laminae. The analysis supports the concept of Rexed's cytoarchitectonic lamination of the dorsal horn.

journal_name

J Neurosci Methods

authors

Milosević NT,Ristanović D,Stanković JB

doi

10.1016/j.jneumeth.2005.02.009

subject

Has Abstract

pub_date

2005-08-15 00:00:00

pages

198-204

issue

2

eissn

0165-0270

issn

1872-678X

pii

S0165-0270(05)00063-4

journal_volume

146

pub_type

杂志文章
  • Representing spike trains using constant sampling intervals.

    abstract::Sensory neurons encode external information by a series of times of action potentials, which is called a spike train. However, since it is a point process, it is hard to analyze. Here we propose a method for converting a spike train into a real-valued time series with a fixed sampling interval under the assumption of ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2009.06.030

    authors: Hirata Y,Aihara K

    更新日期:2009-10-15 00:00:00

  • A biplanar slice preparation for studying cerebellar synaptic transmission.

    abstract::Unlike certain other brain areas, notably the hippocampal formation, synaptic transmission in the cerebellum, a 3-dimensional anatomical structure, is no ideally studied in a 2-dimensional slice preparation. We describe a method for cutting a cerebellar slice that incorporates two planes of section: one sagittal (in t...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(95)00133-6

    authors: Garthwaite J,Batchelor AM

    更新日期:1996-02-01 00:00:00

  • Estimation of volume fractions in nervous tissue with an image analyzer.

    abstract::The calculation of volume fractions in nervous tissue is a method often used in neuroanatomy. In ontogenetic studies and problems concerning aging, as well as after experimental procedures, volume fractions are calculated in order to quantify the results. Grey level index (GLI) and grey cell coefficient (GCC) are diff...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(82)90014-0

    authors: Wree A,Schleicher A,Zilles K

    更新日期:1982-07-01 00:00:00

  • A novel AX+/BX- paradigm to assess fear learning and safety-signal processing with repeated-measure designs.

    abstract::One of the core symptoms of anxiety disorders, such as post-traumatic stress disorder, is the failure to overcome feelings of danger despite being in a safe environment. This deficit likely stems from an inability to fully process safety signals, which are cues in the environment that enable healthy individuals to ove...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2013.01.022

    authors: Kazama AM,Schauder KB,McKinnon M,Bachevalier J,Davis M

    更新日期:2013-04-15 00:00:00

  • In vivo gene delivery to the postnatal ferret cerebral cortex by DNA electroporation.

    abstract::Ferrets have been extensively used to unravel the neural mechanisms of coding and processing of visual information, and also to identify the developmental mechanisms underlying the emergence of such a complex and fine-tuned neural system. In recent years numerous tools have been generated that allow studying neural sy...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2009.11.016

    authors: Borrell V

    更新日期:2010-02-15 00:00:00

  • Anterograde tracing method using DiI to label vagal innervation of the embryonic and early postnatal mouse gastrointestinal tract.

    abstract::The mouse is an extremely valuable model for studying vagal development in relation to strain differences, genetic variation, gene manipulations or pharmacological manipulations. Therefore, a method using 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI) was developed for labeling vagal innervat...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2007.03.001

    authors: Murphy MC,Fox EA

    更新日期:2007-07-30 00:00:00

  • Is it possible to generate cerebral evoked potentials with a mechanical stimulus from the duodenum in rats?

    abstract::The study aim was to develop a model to generate cerebral evoked potentials (CEPs) by mechanical distention of the duodenum in rats. Twenty Sprague-Dawley rats were anaesthetized and the EEG recorded from the left and right somatosensory cortices (S1L, S1R). A balloon catheter was implanted into the duodenum. A pneuma...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2007.01.014

    authors: Murrell JC,Mitchinson SL,Johnstone AC,Johnson CB,Barnes GR

    更新日期:2007-05-15 00:00:00

  • A retrograde double-labeling technique for light microscopy. A combination of axonal transport of cholera toxin B-subunit and a gold-lectin conjugate.

    abstract::A light microscopical, non-fluorescent, retrograde double-labeling technique is described. Cholera toxin B-subunit (CTb) and a conjugate of wheatgerm agglutinin and bovine serum albumin coupled to 10 nm gold particles (gold-lectin) are both excellent retrograde tracers and, when visualized by means of immunohistochemi...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(94)00034-e

    authors: Ruigrok TJ,Teune TM,van der Burg J,Sabel-Goedknegt H

    更新日期:1995-09-01 00:00:00

  • Correction for the influence of background muscle activity on stretch reflex amplitudes.

    abstract::Background muscle activity (BGR) exerts a strong influence on stretch reflex amplitudes. While it is considered important to correct for this influence, which method best able to eliminate the effects of BGR remains unknown. We have therefore compared one previously described and one novel correction method which resp...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(93)90152-h

    authors: Bloem BR,van Dijk JG,Beckley DJ,Zwinderman AH,Remler MP,Roos RA

    更新日期:1993-02-01 00:00:00

  • Microstructure with diffusion MRI: what scale we are sensitive to?

    abstract::Diffusion-weighted MRI is the forerunner of the rapidly developed microstructure MRI (μMRI) aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are accessible using different diffusion MRI techniques and the need to weight t...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章,评审

    doi:10.1016/j.jneumeth.2020.108910

    authors: Kiselev VG

    更新日期:2021-01-01 00:00:00

  • MicroRNA expression profiling of hypothalamic arcuate and paraventricular nuclei from single rats using Illumina sequencing technology.

    abstract::MicroRNAs (miRNAs) finely tune messenger RNA (mRNA) expression. As the brain is a highly heterogeneous tissue, physiologically relevant miRNA expression profiling greatly benefits from sampling brain regions or nuclei. MiRNA expression profiling from individual samples is also important for investigating potential dif...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2012.05.033

    authors: Amar L,Benoit C,Beaumont G,Vacher CM,Crepin D,Taouis M,Baroin-Tourancheau A

    更新日期:2012-07-30 00:00:00

  • Recording electrophysiological data on video tape: a superior and less costly alternative to conventional tape recorders.

    abstract::Electrical potentials recorded extracellularly from the sinus gland of the isopod, Oniscus asellus, were stored on video tape with the aid of a digital-audio (DA) processor and a video cassette recorder (VCR). The DA processor transforms the analog signal to digital pulses of equal amplitude and converts these pulses ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(85)90058-5

    authors: Chiang RG,Knobloch CA,Singleton DM,Steel CG,Davey KG

    更新日期:1985-10-01 00:00:00

  • RNAlater facilitates microdissection of sensory cell-enriched samples from the mouse cochlea for transcriptional analyses.

    abstract::Molecular analyses of cochlear pathology rely on the acquisition of high-quality cochlear samples. For small rodents, isolating sensory cell-enriched samples with well-preserved RNA integrity for transcriptional analyses poses a significant challenge. Here, we report a microdissection technique for isolating sensory c...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2013.08.010

    authors: Cai Q,Wang B,Patel M,Yang SM,Hu BH

    更新日期:2013-10-15 00:00:00

  • Anatomical specificity of functional amygdala imaging of responses to stimuli with positive and negative emotional valence.

    abstract::Non-invasive neuroimaging is increasingly used for investigating the human amygdala. Accurate functional localization in the amygdala region is, however, challenging and quantitative data on the anatomical specificity of functional amygdala imaging is lacking. We have therefore retrospectively investigated 114 recentl...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2009.02.022

    authors: Ball T,Derix J,Wentlandt J,Wieckhorst B,Speck O,Schulze-Bonhage A,Mutschler I

    更新日期:2009-05-30 00:00:00

  • Mechanomyographic activity in the human lateral pterygoid muscle during mandibular movement.

    abstract::The activity of the lateral pterygoid muscle has been regarded to be related to the pathological condition of the temporomandibular joint (TMJ) in the craniomandibular disorders. Because the lateral pterygoid muscle is a deep muscle, a needle electrode is necessary for EMG recordings. The purpose of this study was to ...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2011.09.026

    authors: Kawakami S,Kodama N,Maeda N,Sakamoto S,Oki K,Yanagi Y,Asaumi J,Maeda T,Minagi S

    更新日期:2012-01-15 00:00:00

  • The role of diversity in complex ICA algorithms for fMRI analysis.

    abstract:BACKGROUND:The widespread use of data-driven methods, such as independent component analysis (ICA), for the analysis of functional magnetic resonance imaging data (fMRI) has enabled deeper understanding of neural function. However, most popular ICA algorithms for fMRI analysis make several simplifying assumptions, thus...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2016.03.012

    authors: Du W,Levin-Schwartz Y,Fu GS,Ma S,Calhoun VD,Adalı T

    更新日期:2016-05-01 00:00:00

  • A method for closed-loop presentation of sensory stimuli conditional on the internal brain-state of awake animals.

    abstract::Brain activity often consists of interactions between internal-or on-going-and external-or sensory-activity streams, resulting in complex, distributed patterns of neural activity. Investigation of such interactions could benefit from closed-loop experimental protocols in which one stream can be controlled depending on...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2013.02.020

    authors: Rutishauser U,Kotowicz A,Laurent G

    更新日期:2013-04-30 00:00:00

  • Behavioral phenotyping of minipigs transgenic for the Huntington gene.

    abstract:BACKGROUND:While several novel therapeutic approaches for HD are in development, resources to conduct clinical trials are limited. Large animal models have been proposed to improve assessment of safety, tolerability and especially to increase translational reliability of efficacy signals obtained in preclinical studies...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2015.11.013

    authors: Schramke S,Schuldenzucker V,Schubert R,Frank F,Wirsig M,Ott S,Motlik J,Fels M,Kemper N,Hölzner E,Reilmann R

    更新日期:2016-05-30 00:00:00

  • In vivo visualization of callosal pathways: a novel approach to the study of cortical organization.

    abstract::I describe here the successful visualization of interhemispheric callosal connections in the live mammalian cortex. The development of this method was prompted by the finding that fluorescent tracer labeling of groups of cortical neurons, when done under optimal conditions, is sufficiently intense to be visible even i...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(88)90137-9

    authors: Malach R

    更新日期:1988-10-01 00:00:00

  • Cognitive assessment strategies in Huntington's disease research.

    abstract::The number of studies examining cognition in Huntington's disease (HD) has increased dramatically in recent decades, and cognitive research methods in HD have become much more sophisticated. In this review, we provide a summary of the advances in cognitive research in HD to date, and outline the key considerations for...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章,评审

    doi:10.1016/j.jneumeth.2015.12.007

    authors: Stout JC,Glikmann-Johnston Y,Andrews SC

    更新日期:2016-05-30 00:00:00

  • MARDER--multi-axes rotation device for experimental research. A new concept for investigations of the vestibular, oculomotor, and visual systems of humans in three-dimensional space.

    abstract::A hydraulically driven, digitally servo-controlled multi-axes rotary chair is described. This device generates motion profiles with the subjects head in the center of rotation mainly in order to adequately stimulate the semicircular canals which are sensitive sensors for angular accelerations. This newly developed app...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(93)90108-4

    authors: Probst T,Dabrowski H,Liebler G,Wist ER

    更新日期:1993-08-01 00:00:00

  • Effects of estrous stage and time of day on prepulse inhibition in female rats.

    abstract::Prepulse inhibition (PPI) of the acoustic startle response is a measure of sensory motor gating, and is affected in various neuropsychiatric disorders. Although PPI has been used extensively to study both the neural effects of such conditions, as well as in the search for animal models, a number of critical issues hav...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2008.06.014

    authors: Adams AL,Hudson A,Ryan CL,Doucette TA

    更新日期:2008-08-30 00:00:00

  • The separation and quantification of aminochromes using high-pressure liquid chromatography with electrochemical detection.

    abstract::There is increasing evidence that oxidative stress plays an important role in the pathogenesis of many neurodegenerative diseases including Parkinson's disease (PD). In particular there is support for the participation of oxidized catecholamines in PD. Catecholamines are highly reactive and are readily oxidized to ami...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2004.08.010

    authors: Ochs SD,Westfall TC,Macarthur H

    更新日期:2005-03-30 00:00:00

  • Modification of commercially available image analysis software for semi-automated qualitative analysis of axon regeneration and myelination in the rat sciatic nerve.

    abstract:BACKGROUND:Manual measurement of three routine parameters of axon regeneration and myelination, such as axon counts, axon caliber and G-Ratio, is tedious and time consuming. An automated or semi-automated computer program could improve the efficiency of this process. The concern, however, is that the automated method w...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2014.05.032

    authors: Isaacs J,Mallu S,Batchelor M

    更新日期:2014-08-15 00:00:00

  • Non-contact eye-tracking on cats.

    abstract::The objective of visual systems neuroscience has shifted over the past few years from determining the receptive fields of cells towards the understanding of higher level cognition in awake animals viewing natural stimuli. In experiments with awake animals it is important to control the relevant aspects of behavior. Mo...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(01)00423-x

    authors: Körding KP,Kayser C,Betsch BY,König P

    更新日期:2001-09-30 00:00:00

  • A simple method for quantifying changes in neuronal populations in primary cultures of dissociated rat brain.

    abstract::A simple method which allows easy quantification of neuronal and glial sub-populations in primary neuronal tissue culture is described. The method takes advantage of the fact that the staining of neuronal and glia nuclei with Hoechst 33258 is distinctive and characteristic of the cell type. Double-staining experiments...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(94)00207-w

    authors: Tucker LM,Morton AJ

    更新日期:1995-07-01 00:00:00

  • Monosodium urate test: a new analgesic test by crystal-induced monoarthritis in rats.

    abstract::The analgesic effects of various agents were evaluated in knee joint monoarthritic rats where arthritis was induced by monosodium urate (MSU) crystals injected into the knee joint cavities. The weight supported by each hind limb was measured quantitatively using pressure transducers, which revealed dose-dependent reco...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/0165-0270(90)90026-c

    authors: Otsuki T,Agatsuma Y,Jokura H,Sakurada S,Kisara K,Yoshimoto T

    更新日期:1990-08-01 00:00:00

  • Modified herpes simplex virus delivery of enhanced GFP into the central nervous system.

    abstract::Controlled expression of proteins is a key experimental approach to a deeper understanding of the molecular basis of neuronal function. Here we evaluate the HSV-1 (herpes simplex virus) amplicon vector for gene delivery into the brains of living rats. We demonstrate that HSV-1 amplicon vectors expressing enhanced gree...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(02)00262-5

    authors: Sandler VM,Wang S,Angelo K,Lo HG,Breakefield XO,Clapham DE

    更新日期:2002-12-15 00:00:00

  • Measuring N-acetylaspartate synthesis in vivo using proton magnetic resonance spectroscopy.

    abstract::N-Acetylaspartate (NAA) is an important marker of neuronal function and viability that can be measured using magnetic resonance spectroscopy (MRS). In this paper, we proposed a method to measure NAA synthesis using proton MRS with infusion of uniformly (13)C-labeled glucose, and demonstrated its feasibility in an in v...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/j.jneumeth.2008.04.001

    authors: Xu S,Yang J,Shen J

    更新日期:2008-07-15 00:00:00

  • A low-noise flexible integrated system for recording and analysis of multiple electrical signals during sleep-wake states in rats.

    abstract::A low-noise flexible system for the simultaneous recording and analysis of several electrical signals (EEG, ECG, EMG, and diaphragm EMG) from the same rat was constructed for studying changes in physiological functions during the sleep-wake cycle. The hardware in the system includes a multichannel amplifier, a video c...

    journal_title:Journal of neuroscience methods

    pub_type: 杂志文章

    doi:10.1016/s0165-0270(02)00146-2

    authors: Shaw FZ,Lai CJ,Chiu TH

    更新日期:2002-07-30 00:00:00