Clinical manifestations of mannan-binding lectin deficiency.

Abstract:

:Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency may lead to disease. With examples, this review illustrates the diversity of results obtained so far.

journal_name

Mol Immunol

journal_title

Molecular immunology

authors

Thiel S,Frederiksen PD,Jensenius JC

doi

10.1016/j.molimm.2005.06.018

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

86-96

issue

1-2

eissn

0161-5890

issn

1872-9142

pii

S0161-5890(05)00197-5

journal_volume

43

pub_type

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