Abstract:
PURPOSE:To evaluate the outcome of posterior capsule opacification (PCO) after implantation in rabbit eyes of currently available 3-piece and 1-piece hydrophobic acrylic intraocular lenses (IOLs) with square optic edges. SETTING:John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS:The 3-piece designs evaluated were the AR40e (Advanced Medical Optics Inc.) and the MA60AC (Alcon, Inc.); the 1-piece designs were the SA60AT and the SA30AT (Alcon, Inc.). Nine lenses of each type were implanted in a randomized manner by the same surgeon in 18 Dutch Belted pigmented rabbits. After a follow-up of 3 weeks, the rabbits were killed and analyses of the enucleated eyes were performed from the posterior or Miyake-Apple view. The intensity of central PCO, peripheral PCO, and Soemmering's ring formation was scored from 0 to 4. The area of Soemmering's ring formation was also scored from 0 to 4 based on the number of quadrants involved. Other parameters analyzed were capsulorhexis coverage of the IOL anterior surface, IOL centration, fixation, and presence of striae. Results from the posterior view were complemented by histopathologic evaluation of the eyes. RESULTS:No statistically significant difference was found between the 4 groups of IOLs in the parameters analyzed from the posterior view. When cell ingrowth occurred with the 1-piece designs, causing peripheral and central PCO formation, it was more likely to start at the optic-haptic junctions, as observed during the clinical follow-up with slitlamp examination and confirmed by gross and histopathologic analyses of the enucleated eyes. CONCLUSIONS:The square, truncated optic edge is the most important IOL design feature for PCO prevention. The optic-haptic junctions of the 1-piece designs appear to be sites where the barrier effect of the truncated optic edge is less effective.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Werner L,Mamalis N,Izak AM,Pandey SK,Davis BL,Nilson CD,Weight C,Apple DJdoi
10.1016/j.jcrs.2004.06.088subject
Has Abstractpub_date
2005-04-01 00:00:00pages
805-11issue
4eissn
0886-3350issn
1873-4502pii
S0886-3350(04)00893-4journal_volume
31pub_type
杂志文章abstract::This report describes a series of six children who had a retropseudophakic vitrectomy performed via a limbal approach (limbal approach retropseudophakic vitrectomy, LARV). This technique ensures a permanently clear visual axis when performed at the time of cataract/implant surgery and can also be used to excise second...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80985-6
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To evaluate the in vitro antimicrobial activity of aqueous humor in patients who had preoperative topical application of moxifloxacin hydrochloride 0.5%. SETTING:Department of Ophthalmology, Santa Casa de Misericórdia de São Paulo, Brazil. DESIGN:Comparative case series. METHODS:Twenty-nine eyes from 29 cata...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.11.010
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To compare near vision and quality of vision after controlling for pseudoaccommodation in patients with single-optic accommodating intraocular lenses (IOLs) or monofocal IOLs targeted for mini-monovision. SETTING:Clinical practice. DESIGN:Prospective randomized controlled clinical trial. METHODS:Patients wer...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcrs.2012.08.059
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To compare the efficiencies of the operative procedures and the reductions in postoperative corneal endothelial cell density (ECD) after cataract surgery using 2 different phacoemulsification tips and their associated cassettes and tubing. SETTING:Wolfe Clinic, Marshalltown, Iowa, USA. METHODS:A randomized pr...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(99)00201-1
更新日期:1999-10-01 00:00:00
abstract::We report a case of late-onset diffuse lamellar keratitis (DLK) in the left eye of a 56-year-old white woman 3 years after uneventful bilateral laser in situ keratomileusis (LASIK). Slitlamp examination revealed stage 3 DLK with diffuse, multifocal, dot-like, and granular haze in the interface. The DLK did not have an...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2004.05.054
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:To compare epithelial remodeling in keratoconic eyes that had photorefractive keratectomy and corneal collagen crosslinking (Athens protocol) with that in untreated keratoconic eyes and healthy eyes. SETTING:Private clinical practice, Athens, Greece. DESIGN:Comparative case series. METHODS:Fourier-domain ant...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.02.036
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To evaluate the influence of preoperative variables and early postoperative intraocular pressure (IOP) on the loss of corneal endothelial cells after phacoemulsification in eyes with occludable angles. SETTING:Taipei Veterans General Hospital, Taipei, Taiwan. METHODS:Sixty patients with occludable angles havi...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2007.07.057
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To compare the long-term longitudinal visual acuity outcomes after cataract surgery in eyes with age-related macular degeneration (AMD) at surgery and eyes without comorbidity. SETTING:University-based eye clinic. DESIGN:Longitudinal cohort study. METHODS:Patients having cataract surgery were evaluated over ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2011.09.041
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To compare the spatial resolution threshold in the central visual field of pseudophakic patients with monofocal and multifocal intraocular lenses (IOLs). SETTING:Eye Clinic, University of Trieste, Italy. METHODS:Twenty phakic normal subjects and four groups of 20 pseudophakic patients each, implanted with ref...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(98)80206-x
更新日期:1998-02-01 00:00:00
abstract::We discuss a case of bipseudophakia with secondary dislocation of a posterior chamber intraocular lens (IOL) into the anterior chamber that was managed by explantation of the anterior and posterior chamber IOLs and implantation of an iris claw IOL. ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01991-0
更新日期:2003-07-01 00:00:00
abstract::The postoperative astigmatic course of unsutured and sutured 4.0 mm scleral pocket incisions was followed for one year in a small pilot study. Initially, with-the-rule changes were noted only in the sutured group; eventually both groups demonstrated a small against-the-rule change that did not differ clinically or sta...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80607-4
更新日期:1993-07-01 00:00:00
abstract:PURPOSE:To compare corneal endothelial damage after cataract surgery in eyes with low endothelial cell density (ECD) and eyes with normal ECD. SETTING:Hayashi Eye Hospital, Fukuoka, Japan. DESIGN:Case-control study. METHODS:Cataract surgery was performed in eyes with a low ECD (500 to 1000 cells/mm(2)) (low-density ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2011.02.025
更新日期:2011-08-01 00:00:00
abstract::We received approval from the U.S. implant Food and Drug Administration and the University's Institutional Review Board to the Artisan lens (Ophtec BV) in both eyes of a patient who was aphakic and had megalocornea. No other intraocular lens would easily solve this patient's need because of the large anterior segment....
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.12.060
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:To evaluate the safety of a new suprachoroidal device, the Cypass micro-stent, for the surgical treatment of open-angle glaucoma (OAG) implanted in conjunction with cataract surgery. SETTING:Multicenter clinical study. DESIGN:Prospective interventional case series. METHODS:This is an interim report of an ong...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcrs.2012.10.040
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To compare the effect of erbium:YAG laser photocapsulotomy (ELC), continuous curvilinear capsulorhexis (CCC), and high-frequency capsulotomy (HFC) on anterior capsule edges using light microscopy (LM) and transmission electron microscopy (TEM). SETTING:Department of Ophthalmology, Department of Histology and E...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/S0886-3350(03)00652-7
更新日期:2004-01-01 00:00:00
abstract::Phacoemulsification with intraocular lens (IOL) implantation was performed in the right eye of an 84-year-old woman using a small clear corneal incision. Ten weeks after surgery, the patient fell, which caused traumatic iridodialysis and hyphema with expulsion of the iris through the surgical corneal incision. Apart f...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2004.03.040
更新日期:2004-10-01 00:00:00
abstract::We present a simple, effective technique to remove an intraocular lens (IOL) via a very small incision (2.2 mm). After the IOL is carefully removed from the capsular bag, into the anterior chamber, 2 radial incisions, 35 degrees to 50 degrees apart, are made with a Vannas scissors. This results in 2 IOL pieces (maximu...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.02.036
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:To assess the safety and effectiveness of an immunotoxin, MDX-RA, designed to inhibit posterior capsule opacification (PCO). SETTING:Eleven private practices in the United States. METHODS:This study comprised 63 eyes of 63 patients having extracapsular cataract extraction by phacoemulsification; these patient...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0886-3350(98)80352-0
更新日期:1998-12-01 00:00:00
abstract::We report the case of a 70-year-old woman with a history of acute primary angle-closure glaucoma (PACG) in the left eye who, 2 hours after a fundus examination and mydriasis, experienced acutely elevated intraocular pressure (IOP) up to 40 mm Hg in the presence of fully dilated pupil and a patent iridotomy. Gonioscopy...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2003.10.027
更新日期:2004-06-01 00:00:00
abstract::Descemet-stripping automated endothelial keratoplasty (DSAEK) is an alternative to penetrating keratoplasty for the treatment of corneal endothelial disease that involves stripping diseased Descemet membrane (DM) from the recipient. Descemet membrane stripping is currently performed with a generic balanced salt soluti...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2008.01.037
更新日期:2008-06-01 00:00:00
abstract:PURPOSE:To determine the precision and accuracy of an artificial anterior chamber and a manual microkeratome in obtaining corneal lenticules for lamellar keratoplasty. SETTING:Department of Ophthalmology, Cornea, External Diseases and Refractive Surgery Service, University of California Irvine, Irvine, California, USA...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)00896-3
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To determine predictors of long-term intraocular pressure (IOP) after cataract surgery. SETTING:Hunter Holmes McGuire Veterans Administration Hospital, Richmond, Virginia, USA. DESIGN:Case series. METHODS:Clinical variables, IOP by applanation tonometry, anatomic features on anterior segment optical coherenc...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2011.07.033
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of phenylephrine 1.0%-ketorolac 0.3% (Omidria) for maintenance of mydriasis during, and reduction of ocular pain after, cataract surgery. SETTING:Twenty centers in the United States and the Netherlands. DESIGN:Prospective randomized clinical trials. METHODS:Patients having...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jcrs.2015.10.053
更新日期:2015-10-01 00:00:00
abstract:UNLABELLED:We describe a recently developed chopper, the retrochopper, and a technique for managing black and brunescent cataracts. The technique enables the surgeon to effectively disassemble the nucleus and perform a safe procedure with a short learning curve. FINANCIAL DISCLOSURE:No author has a financial or propri...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2013.03.015
更新日期:2013-06-01 00:00:00
abstract::Sixty-six consecutive cases of extracapsular cataract extraction (ECCE) and sulcus implantation of a posterior chamber lens had intraocular pressure (IOP) measurements recorded four months postoperatively. These results were compared to the fellow unoperated eyes, as well as to a group of 64 patients, whom we reported...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(87)80007-x
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:To evaluate the influence of a capsular bending ring (CBR) or tension ring (CTR) on capsular bag shrinkage. SETTING:Department of Ophthalmology, Johannes Gutenberg-University, and Department of Medical Biometry, Epidemiology and Informatics, University of Mainz, Mainz, Germany. METHODS:In 92 eyes of 92 patien...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcrs.2005.06.046
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:To assess the capability of new software to decrease the proportion of eyes that have insufficient signal-to-noise ratio (SNR) in optical biometry. SETTING:Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. DESIGN:Evaluation of diagnostic test or technology. METHODS:In a prospective study,...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2010.07.023
更新日期:2011-01-01 00:00:00
abstract::We present a case of traumatic lens subluxation that was evident only when the patient was in the supine position. This case illustrates that a crystalline lens with traumatic zonular rupture can change its position depending on the posture of the patient. If such a lens is suspended by the remaining zonules at the su...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)01167-1
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:To compare the visual acuity outcomes and the ocular and intraocular optical quality in patients with a monofocal intraocular lens (IOL) or a new-generation single-optic accommodating IOL. SETTING:Vissum Corporation, Alicante, Spain. DESIGN:Comparative case series. METHODS:Consecutive eyes of bilateral catar...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2010.04.040
更新日期:2010-10-01 00:00:00
abstract::We used ultrasound to measure axial length in 66 eyes before and three months after extracapsular cataract extraction with implantation of a posterior chamber lens. An ultrasound velocity of 2,718 m/s for poly(methyl methacrylate) was assumed. The intraindividually measured difference (postoperative--preoperative axia...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(89)80035-5
更新日期:1989-11-01 00:00:00