Abstract:
:Even with the help of modern pharmacology, treatment of erectile dysfunction often remains complex, and requires taking into account the social, psychological, and behavioral dimensions of the disorder. This brief report presents a case study highlighting this complexity.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Bianchi-Demicheli F,Ortigue S,De Ziegler D,Damsa C,Sekoranja Ldoi
10.1038/sj.ijir.3901322subject
Has Abstractpub_date
2005-07-01 00:00:00pages
381-2issue
4eissn
0955-9930issn
1476-5489pii
3901322journal_volume
17pub_type
杂志文章abstract::The aims of this study were to investigate the prevalence of ED in Chinese men with type 2 diabetes mellitus, and evaluate the efficacy and safety of sildenafil citrate in these patients. Patients from 42 outpatient diabetes clinics with type 2 diabetes mellitus and ED as defined by the International Index of Erectile...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2010.21
更新日期:2010-09-01 00:00:00
abstract::We studied the association between erythrocyte aggregation (EA) and erectile dysfunction (ED) in men with coronary artery disease (CAD). Men with CAD documented by coronary angiography filled the Sexual Health Inventory for Males questionnaire to detect ED and assess its severity. EA was evaluated by filming slides of...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2009.6
更新日期:2009-05-01 00:00:00
abstract::The objective of this study is to investigate whether the L-arginine/nitric oxide pathway is involved in the neurotransmission of paraventricular nucleus of hypothalamus (PVN) activation-induced penile erection in the rat. Male adult Sprague-Dawley rats anesthetized with pentobarbital were used. The femoral artery was...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900825
更新日期:2002-06-01 00:00:00
abstract::A lack of uniformity exists for insurance payer coverage for all categories of penile prostheses (PP). We sought to determine common insurance coverage criteria and barriers to implantation across common insurance plans from healthcare referral regions (HRR) nationwide. Coverage criteria and stipulations were reviewed...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/s41443-019-0226-8
更新日期:2021-01-01 00:00:00
abstract::The release of mediator substances of the arachidonic acid cascade is closely related to the functional state of the endothelium. A significant lower prostacyclin/thromboxane A2 ratio in penile plasma of organogenic impotent patients in comparison to patients with psychogenic erectile dysfunction has been described in...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::Although several studies on toxic effect of aspartame metabolite have been studied, controversial reports over the use of aspartame owing to the fact that it releases methanol as one of its metabolite during metabolism exist. This present study is proposed to investigate whether aspartame (40 mg kg-1 b.wt) administrat...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2017.17
更新日期:2017-07-01 00:00:00
abstract::Routine removal of the reservoir in explanting a malfunctioning three-piece penile implant raises debates because that the retained reservoir has little risk of erosion and it often needs a second incision to remove the reservoir. We reported a case whose retained reservoir resulted in nonbacterial inflammation around...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901402
更新日期:2006-05-01 00:00:00
abstract::At this present time there is a serious gap in our understanding of how psychological difficulties result in specific sexual dysfunction. In this paper, a theoretical model of sexual response is proposed which involves the parallel existence of excitatory and inhibitory mechanisms in the central nervous system. Eviden...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract::We have investigated the reliability of intracavernosal prostaglandin E1 (PGE1) office vs self-injection therapy in patients with erectile dysfunction (ED). A total of 298 male patients with ED were enrolled in this study. In all patients, intracavernosal titration of the PGE1 dose was performed. A total of 106 patien...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901388
更新日期:2006-03-01 00:00:00
abstract::Erectile dysfunction (ED) develops owing to psychogenic, organic or/and both of these two factors. The aim of this study was to investigate the relationship between penile cavernosal arterial flow and peripheral atherosclerosis in men with ED. This study was conducted on 102 patients who had presented to Radiology Cli...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2013.35
更新日期:2014-03-01 00:00:00
abstract::We investigated whether coronary flow reserve (CFR) can be modified by tadalafil, a long-acting phosphodiesterase 5 (PDE5) inhibitor, in patients with documented coronary artery disease (CAD). CFR was non-invasively evaluated in 12 men with a positive history for erectile dysfunction (ED) and angiographically document...
journal_title:International journal of impotence research
pub_type: 临床试验,杂志文章
doi:10.1038/sj.ijir.3901592
更新日期:2008-03-01 00:00:00
abstract::Sildenafil is one of two oral drugs approved for first-line treatment of erectile dysfunction (ED). Anecdotally, some young healthy men who wish to enhance their sexual performance are requesting or abusing sildenafil. In this randomized double-blind, placebo-controlled clinical study, we investigated the effect of si...
journal_title:International journal of impotence research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ijir.3901005
更新日期:2003-06-01 00:00:00
abstract::We estimated the incidence of erectile dysfunction (ED) in a population-based sample during 5-y follow-up and determined how the rate was affected by sociodemographic and life-style factors. The target population comprised all men aged 50, 60 or 70 y residing in the city of Tampere or 11 surrounding municipalities in ...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901196
更新日期:2004-10-01 00:00:00
abstract::Soluble guanylyl cyclase (sGC) is the major effector molecule for nitric oxide (NO) and as such an interesting therapeutic target for the treatment of erectile dysfunction. To assess the functional importance of the sGCalpha(1)beta(1) isoform in corpus cavernosum (CC) relaxation, CC from male sGCalpha(1)(-/-) and wild...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901627
更新日期:2008-05-01 00:00:00
abstract::Hard flaccid (HF) is a group of symptoms that significantly affects a man's sexual and social life. As this syndrome has only been reported in several patient forums, exact prevalence of this rare condition is unknown. Currently, no scientific literature exists of the syndrome. We, hereby, aimed to present four cases ...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/s41443-019-0133-z
更新日期:2020-03-01 00:00:00
abstract::This study examined the effects of a new phosphodiesterase type 5 inhibitor, DA-8159, on erectile function associated with hypercholesterolemia. First of all, in order to investigate whether chronic administration of DA-8159 prevents the development of erectile dysfunction associated with hypercholesterolemia, male SD...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901331
更新日期:2005-09-01 00:00:00
abstract::We sought to establish the interplay of metabolic syndrome (MetS) and/or sexual dysfunction (SD) on hypogonadism. Sexual functioning was assessed using Golombok Rust Inventory of Sexual Satisfaction in 274 consecutive diabetic men visiting the diabetic clinic of the Tema General Hospital between November 2010 and Marc...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2017.6
更新日期:2017-05-01 00:00:00
abstract::Erectile dysfunction (ED) is defined as the inability to attain and maintain erection of the penis sufficient to permit satisfactory sexual activity. ED most commonly affects men from 40 years of age with a clear age-associated increase in prevalence. The condition may have significant negative impact on quality of li...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:10.1038/s41443-019-0132-0
更新日期:2019-05-01 00:00:00
abstract::The aim of this work was to characterize the effect of experimental diabetes on neurotransmission in rat vagina. Female Sprague-Dawley rats were divided into two groups: non-diabetic controls (NDM, n=38) and diabetics (DM, n=38). DM was produced by intraperitoneal injection of streptozotocin. Eight weeks later the ani...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900648
更新日期:2001-04-01 00:00:00
abstract::Sildenafil has had a dramatic influence on the field of sexual medicine over the past 20 years. Not only have phosphodiesterase-5 (PDE5) inhibitors improved the treatment of erectile dysfunction (ED), they have indirectly contributed to the treatment of male factor infertility. A review of the literature between 1998 ...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:10.1038/s41443-018-0067-x
更新日期:2019-03-01 00:00:00
abstract::Both RigiScan and the Snap Gauge band devices are used to objectively measure penile rigidity. The Snap Gauge band is the more simple and inexpensive of the two techniques. We investigated the correlation between the results obtained by both devices in order to evaluate whether the Snap Gauge band could be employed as...
journal_title:International journal of impotence research
pub_type: 临床试验,杂志文章
doi:10.1038/sj.ijir.3900438
更新日期:1999-12-01 00:00:00
abstract::Nitric oxide (NO) is a physiologic signal essential to penile erection, and disorders that reduce NO synthesis or release in the erectile tissue are commonly associated with erectile dysfunction. NO synthase (NOS) catalyzes production of NO from L-arginine. While both constitutively expressed neuronal NOS (nNOS) and e...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:10.1038/sj.ijir.3901209
更新日期:2004-06-01 00:00:00
abstract::Despite extensive research into the toxicity of bisphenol A (BPA), no report of its effect on erectile function exists. We performed this study to investigate the effect of BPA on erectile function. New Zealand white rabbits were treated intraperitoneally with 150 mg/kg of BPA every other day for 12 days (cumulative d...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900734
更新日期:2001-10-01 00:00:00
abstract::New Zealand white rabbit cavernosal smooth muscle strips (n=6) were mounted in organ baths. Relaxations to nitric oxide (10(-7)-10(-4) mol/l) were measured and the same procedure was repeated on strips from rabbits 6 months after alloxan-induced diabetes (n=6). Transverse cavernosal sections were obtained from the sam...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900935
更新日期:2002-12-01 00:00:00
abstract::Our interim analysis of a phase II clinical trial on low-intensity extracorporeal shockwave therapy (Li-ESWT) for men with erectile dysfunction (ED) has demonstrated it is safe with no reported adverse outcomes. Interim analysis has demonstrated Sexual Encounter Profile 3 (ability to maintain erection till completion)...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/s41443-019-0115-1
更新日期:2019-05-01 00:00:00
abstract::The objective was to study available evidence for ingredients of popular over-the-counter testosterone and erectile dysfunction (ED) supplements. The top 16 male testosterone and 16 ED supplements in the USA were identified from the most popular online retailers: A1 Supplements, Amazon, Vitamin Shoppe, and Walmart. In...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/s41443-020-0285-x
更新日期:2020-05-01 00:00:00
abstract::This paper: (i) describes the worldwide prevalence of erectile dysfunction (ED); (ii) presents age-specific incidence rates for ED in the US; (iii) summarizes some key epidemiologic correlates of ED in the general population; and (iv) considers the possibility that ED may be a biobehavioral marker (sentinel event) of ...
journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:10.1038/sj.ijir.3900567
更新日期:2000-10-01 00:00:00
abstract::The objective of the study was to evaluate the relationship between the sexual position and severity of penile fracture (PF). We studied 90 patients with PF. The mechanism of injury and the sexual position was assessed. We divided our sample by the etiology of the fracture in six groups: (a) masturbation or penile man...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/ijir.2017.24
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVES:Our objective was to elucidate the discussion points of circumcision on social media (SoMe) by looking at the Twitter activity. MATERIAL AND METHODS:Twitter searched for #circumcision hashtag via www.tweetarchivist.com , www.twitonomy.com , www.symplur.com . Total tweet numbers, most influencers, top users ...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/s41443-018-0058-y
更新日期:2018-10-01 00:00:00
abstract::Apomorphine SL (TAP Holdings, Deerfield, IL) is a centrally acting treatment for erectile dysfunction (ED) that has been undergoing phase III trials. Over 3000 men have received apomorphine SL and over 75,000 doses have been taken. In the first three phase III parallel arm cross-over double-blind studies 854 patients ...
journal_title:International journal of impotence research
pub_type: 杂志文章,meta分析
doi:10.1038/sj.ijir.3900581
更新日期:2000-10-01 00:00:00