Abstract:
:Manatunga and Chen [A.K. Manatunga, S. Chen, Sample size estimation for survival outcomes in cluster-randomized studies with small cluster sizes, Biometrics 56 (2000) 616-621] proposed a method to estimate sample size and power for cluster-randomized studies where the primary outcome variable was survival time. The sample size formula was constructed by considering a bivariate marginal distribution (Clayton-Oakes model) with univariate exponential marginal distributions. In this paper, a user-friendly FORTRAN 90 program was provided to implement this method and a simple example was used to illustrate the features of the program.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Gao F,Manatunga AK,Chen Sdoi
10.1016/j.cmpb.2004.11.004subject
Has Abstractpub_date
2005-04-01 00:00:00pages
61-7issue
1eissn
0169-2607issn
1872-7565pii
S0169-2607(05)00003-9journal_volume
78pub_type
杂志文章abstract::Cardiac MR image-based predictive models integrating statistical atlases of heart anatomy and fiber orientations can aid in better diagnosis of cardiovascular disease, a major cause of death worldwide. Such atlases have been built from diffusion tensor (DT) images and can be used in anisotropic models for personalized...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105200
更新日期:2020-04-01 00:00:00
abstract::A novel methodology of electrophoretic gel image analysis has been proposed that is based on two-dimensional image processing methods instead of previously used one-dimensional Gaussian deconvolution. The crucial problem of the analysis of imperfect gels, that consists in band detection, is solved using the algorithms...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2004.09.007
更新日期:2005-03-01 00:00:00
abstract::Given longitudinal data for several variables, including a given outcome variable, it is desired to predict the outcome for a specific individual, or more generally experimental unit, in such a way that the predicted value is both accurate and resistant (i.e. has good cross-validation). There are certain data-analytic...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(01)00114-6
更新日期:2002-02-01 00:00:00
abstract::The identification of thousands of mutations yearly has put new challenges to researchers who are interested in fast and effective annotation as well as the prediction of potential implications to the gene regulation mechanisms. This work presents an integrative tool, called GREMET, for the prediction of alterations i...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.04.002
更新日期:2013-07-01 00:00:00
abstract::ODMixed is a computer program to obtain optimal designs for linear mixed models of longitudinal studies. These designs account for heterogeneous correlated errors and for data with dropout. Designs are compared by using relative efficiencies, e.g., between a D-optimal design for homogeneous data and another for hetero...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2010.04.004
更新日期:2011-01-01 00:00:00
abstract::Influence diagrams have been widely used as knowledge bases in medical informatics and many applied domains. In conventional influence diagrams, the numerical models of uncertainty are probability distributions associated with chance nodes and value tables for value nodes. However, when incomplete knowledge or linguis...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2007.11.009
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In recent years, many attempts have been made to design reliable systems for identifying individuals using biometrics. Electrocardiogram (ECG) biometric is one of the newest methods that not only offers unique characteristics of individuals for human identification, but also the possibility of ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.02.009
更新日期:2019-04-01 00:00:00
abstract::The urinary flow rates of normal individuals depend on the initial bladder volume in a non-linear fashion (J. Urol. 109 (1973) 874). A flow rate nomogram was developed by Siroky, Olsson and Krane, (J. Vol. 122 (1979) 665), taking the non-linear relationship into account, as an aid in the interpretation of urinary flow...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(93)90030-o
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Model-based lung mechanics monitoring can provide clinically useful information for guiding mechanical ventilator treatment in intensive care. However, many methods of measuring lung mechanics are not appropriate for both fully and partially sedated patients, and are unable provide lung mechani...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.105184
更新日期:2020-04-01 00:00:00
abstract::The GALEN project is developing language independent concept representation systems as the foundations for the next generation of multilingual coding systems. It aims to support the flexibility required to cope with the diversity amongst medical applications, while ensuring the coherence necessary for integration and ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(94)90020-5
更新日期:1994-10-01 00:00:00
abstract::This study employs the concept of applying constant-phase models to input respiratory impedance data obtained with the non-invasive Forced Oscillation Technique (FOT) lung function test. Changes in respiratory mechanics from healthy and chronic obstructive pulmonary disease (COPD) diagnosed patients are observed with ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2009.06.006
更新日期:2010-01-01 00:00:00
abstract::Cosmetic doctor utilizes the position, size and shapes of female's breast to judge whether the breast is under steady-state condition after breast implant plastic surgery. Since, doctor evaluates the breast condition with the subjective discrimination (such as vision, sense of touch) without using the objective physic...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2007.11.013
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Automatic osteosarcoma tumor segmentation on computed tomography (CT) images is a challenging problem, as tumors have large spatial and structural variabilities. In this study, an automatic tumor segmentation method, which was based on a fully convolutional networks with multiple supervised sid...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.02.013
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Skin cancer is the commonest form of cancer in the worldwide population. Non-invasive and non-contact imaging modalities are being used for the screening of melanoma and other cutaneous malignancies to endorse early detection and prevention of the disease. Traditionally it has been a problem fo...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.06.018
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Estimating patient specific annual risk of rupture of abdominal aortic aneurysm (AAA) is currently based only on population. More accurate knowledge based on patient specific data would allow surgical treatment of only those AAAs with significant risk of rupture. This would be beneficial for bo...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2020.105916
更新日期:2020-12-25 00:00:00
abstract::An integrated experimental and computational procedure is provided for the evaluation of the biomechanical behaviour that characterizes the pressure-volume response of gastrointestinal regions. The experimental activity pertains to inflation tests performed on specific gastrointestinal conduct segments. Different infl...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.06.022
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hedyotis diffusa is an herb used for anti-cancer, anti-oxidant, anti-inflammatory, and anti-fibroblast treatment in the clinical practice of Traditional Chinese Medicine. However, its pharmacological mechanisms have not been fully established and there is a lack of modern scientific verificatio...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2018.10.019
更新日期:2019-06-01 00:00:00
abstract::Traditional gait and fluoroscopy analysis of human movement are largely utilised but are still limited in registration, integration, synchronisation and visualisation capabilities. The present work exploits the features of a recently developed software tool based on multimodal display (Data Manager developed within th...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2005.04.007
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:For diagnosis of arrhythmic heart problems, electrocardiogram (ECG) signals should be recorded and monitored. The long-term signal records obtained are analyzed by expert cardiologists. Devices such as the Holter monitor have limited hardware capabilities. For improved diagnostic capacity, it w...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2019.05.004
更新日期:2019-07-01 00:00:00
abstract::In this article the development of a computer system for General Practice, ELIAS, is described. The use of the 4th-generation software toolkit AIDA proved to be very helpful in increasing the speed of development as well as the quality of the ELIAS software. The programming support that AIDA offered, not only in incre...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(87)90086-1
更新日期:1987-11-01 00:00:00
abstract::Characterization of carotid atherosclerosis and classification into either symptomatic or asymptomatic is crucial in terms of diagnosis and treatment planning for a range of cardiovascular diseases. This paper presents a computer-aided diagnosis (CAD) system (Atheromatic) that analyzes ultrasound images and classifies...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2012.09.008
更新日期:2013-04-01 00:00:00
abstract::Subcutaneous insulin kinetics is a complex process whose quantitation is needed for a reliable glycemic control in the conventional therapy of insulin-dependent diabetes. The major difficulties in modeling include accounting for the distribution in the subcutaneous depot and transport to plasma. A single model describ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章,评审
doi:10.1016/s0169-2607(00)00071-7
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Functional magnetic resonance imaging (fMRI) studies of the human brain are appearing in increasing numbers, providing interesting information about this complex system. Unique information about healthy and diseased brains is inferred using many types of experiments and analyses. In order to ob...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2016.07.015
更新日期:2016-10-01 00:00:00
abstract::The aim of segmentation of tumor regions in positron emission tomography (PET) is to provide more accurate measurements of tumor size and extension into adjacent structures, than is possible with visual assessment alone and hence improve patient management decisions. We propose a segmentation energy function for the g...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2012.10.009
更新日期:2013-03-01 00:00:00
abstract::When analysing postural control statistical characteristics of the centre of pressure or the ground reaction force are often used. A complement would be to analyse movement strategies as well. The purpose of this study was to determine to what extent the ankle strategy is used to maintain the balance in standing. One ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(96)01794-4
更新日期:1997-03-01 00:00:00
abstract::Interventricular septum thickness in end-diastole (IVSd) is one of the key parameters in cardiology. This paper presents a fast algorithm, suitable for pocket-sized ultrasound devices, for measurement of IVSd using 2D B-mode parasternal long axis images. The algorithm is based on a deformable model of the septum and t...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2011.02.011
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Objective Structured Clinical Examination (OSCE) has been used in many areas of healthcare training over the years. However, it constantly needs to be upgraded and enhanced due to technological and teaching changes. We aim at implementing an integrative OSCE method which employs informatics via...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2017.11.006
更新日期:2018-05-01 00:00:00
abstract::Quesenberry and Hurst (1964), Goodman (1965) and Fitzpatrick and Scott (1987) proposed simultaneous construction of confidence intervals for multinomial proportions, however. statistical computing packages do not generally give one the option of specifying the type of construction to be used. We have written a SAS mac...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/s0169-2607(97)01809-9
更新日期:1997-07-01 00:00:00
abstract::In this study, the virtual reality (VR) proprioception rehabilitation system was developed for stroke patients to use proprioception feedback in upper limb rehabilitation by blocking visual feedback. To evaluate its therapeutic effect, 10 stroke patients (onset>3 month) trained proprioception feedback rehabilitation f...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/j.cmpb.2013.09.006
更新日期:2014-01-01 00:00:00
abstract::The use of well characterized laboratory animals in biomedical research is of importance for quality securing and reproducibility of animal experiments. Therefore, breeders should not only have in mind the reproduction of their animal stocks, but they should also be interested to achieve an optimal resemblance of the ...
journal_title:Computer methods and programs in biomedicine
pub_type: 杂志文章
doi:10.1016/0169-2607(92)90076-j
更新日期:1992-06-01 00:00:00