ODmixed: a tool to obtain optimal designs for heterogeneous longitudinal studies with dropout.

Abstract:

:ODMixed is a computer program to obtain optimal designs for linear mixed models of longitudinal studies. These designs account for heterogeneous correlated errors and for data with dropout. Designs are compared by using relative efficiencies, e.g., between a D-optimal design for homogeneous data and another for heterogeneous data or between a D-optimal design for complete data against another that optimizes designs when data is missing at random. Two examples are worked out to illustrate how researchers could use this computer program to profit of optimal design theory at the planning stage of longitudinal studies.

authors

Ortega S,Tan FE,Berger MP

doi

10.1016/j.cmpb.2010.04.004

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

62-71

issue

1

eissn

0169-2607

issn

1872-7565

pii

S0169-2607(10)00089-1

journal_volume

101

pub_type

杂志文章
  • The moment segmentation analysis of heart sound pattern.

    abstract:UNLABELLED:This paper presents two new ideas. The first one is to apply the Viola integral waveform method to analyze the heart sounds recorded by an electric stethoscope, and the multi-scale moment analysis is proposed to locate each cycle of heart sounds. A fast algorithm for calculating characteristic waveform (CW) ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2009.09.008

    authors: Yan Z,Jiang Z,Miyamoto A,Wei Y

    更新日期:2010-05-01 00:00:00

  • A knowledge-based system for real-time quality control and fault diagnosis of multitest analyzers.

    abstract::A PC-based real-time quality control (QC) system for multitest analyzers has been developed as a prototype. The system is built with use of a relational database management system (DBMS). Control values from the various analytical channels are stored and administrated with use of the DBMS. The control values collected...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(91)90042-r

    authors: Groth T,Modèn H

    更新日期:1991-02-01 00:00:00

  • An application of the microcomputer as a generator of target movements for the eye tracking test (ETT).

    abstract::We have developed a new system to produce target movements for our particular purposes using a microcomputer and 9-bit digital-to-analog converter. A continuously changing sinusoidal wave was produced to examine the relationship between the frequencies of target movements and smooth pursuit. A random sinusoidal wave w...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(86)90057-x

    authors: Ohashi N,Watanabe Y,Imamura J,Takeda S,Mizukoshi K

    更新日期:1986-12-01 00:00:00

  • How the gender of a victim character in a virtual scenario created to learn CPR protocol affects student nurses' performance.

    abstract:BACKGROUND AND OBJECTIVE:Virtual simulations recreate scenarios where student nurses can practice procedures in a safe and supervised manner and with no risk to the patient. Virtual scenarios include digital characters that reproduce human actions. Generally, these characters are modeled as males and restricted roles a...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2018.05.019

    authors: Boada I,Rodriguez-Benitez A,Thió-Henestrosa S,Olivet J,Soler J

    更新日期:2018-08-01 00:00:00

  • Analysis of parameters affecting blood oxygen saturation and modeling of fuzzy logic system for inspired oxygen prediction.

    abstract:BACKGROUND AND OBJECTIVE:Fraction of Inspired Oxygen is one of the arbitrary set ventilator parameters which has critical influence on the concentration of blood oxygen. Normally mechanical ventilators providing respiratory assistance are tuned manually to supply required inspired oxygen to keep the oxygen saturation a...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2019.04.014

    authors: Radhakrishnan S,Nair SG,Isaac J

    更新日期:2019-07-01 00:00:00

  • OctNET: A Lightweight CNN for Retinal Disease Classification from Optical Coherence Tomography Images.

    abstract:BACKGROUND AND OBJECTIVE:Retinal diseases are becoming a major health problem in recent years. Their early detection and ensuing treatment are essential to prevent visual damage, as the number of people affected by diabetes is expected to grow exponentially. Retinal diseases progress slowly, without any discernible sym...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2020.105877

    authors: A P S,Kar S,S G,Gopi VP,Palanisamy P

    更新日期:2020-11-28 00:00:00

  • An iterative phase correction program for nuclear magnetic resonance (NMR) spectra.

    abstract::An iterative algorithm is given to correct for the zeroth and first order phase errors in NMR spectroscopy. A FORTRAN computer program is listed and two sample runs exemplified. No a priori knowledge of the existing phase errors is required. The parameters are optimised iteratively under the assumption that when the s...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(88)90078-8

    authors: Chen CN,Kan LS

    更新日期:1988-01-01 00:00:00

  • Novel atlas of fiber directions built from ex-vivo diffusion tensor images of porcine hearts.

    abstract::Cardiac MR image-based predictive models integrating statistical atlases of heart anatomy and fiber orientations can aid in better diagnosis of cardiovascular disease, a major cause of death worldwide. Such atlases have been built from diffusion tensor (DT) images and can be used in anisotropic models for personalized...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2019.105200

    authors: Mojica M,Pop M,Sermesant M,Ebrahimi M

    更新日期:2020-04-01 00:00:00

  • DIABLOG: a simulation program of insulin-glucose dynamics for education of diabetics.

    abstract::This paper presents a dialogue computer program, DIABLOG, for the education of diabetic patients with insulin therapy. Through mathematical modelling of glucose-insulin dynamics this program is able to simulate glucose and insulin profiles of a 24 h period and display them graphically as curves. The subjects could var...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(90)90114-o

    authors: Biermann E,Mehnert H

    更新日期:1990-07-01 00:00:00

  • A tracer metric numerical model for predicting tortuosity factors in three-dimensional porous tissue scaffolds.

    abstract::One of the critical functions of a tissue-engineered construct is to be able to provide adequate nutrient and oxygen supply into the interior of the construct. An insufficient supply will lead to slower cellular proliferation rates and eventual apoptosis. The supply of the nutrients is largely governed by the transpor...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2007.04.003

    authors: Starly B,Yildirim E,Sun W

    更新日期:2007-07-01 00:00:00

  • A software for the description of workplaces in the PRS system.

    abstract::Workplace description is an operation indispensable for the identification of professional risks and, in fulfillment of that objective, can best be accomplished by listing the constituent tasks associated with each job. This article presents a software in Visual-Basic to be run on a portable micro-computer, which faci...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/s0169-2607(97)01777-x

    authors: Martin JM,Dartois E,Bontoux-Frank G,Ricour B,Pariset L,Robaux P,Giampietro V

    更新日期:1997-01-01 00:00:00

  • Fourier-based quantification of renal glomeruli size using Hough transform and shape descriptors.

    abstract:BACKGROUND AND OBJECTIVE:Analysis of glomeruli geometry is important in histopathological evaluation of renal microscopic images. Due to the shape and size disparity of even glomeruli of same kidney, automatic detection of these renal objects is not an easy task. Although manual measurements are time consuming and at t...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.08.011

    authors: Najafian S,Beigzadeh B,Riahi M,Khadir Chamazkoti F,Pouramir M

    更新日期:2017-11-01 00:00:00

  • Joint optic disc and cup boundary extraction from monocular fundus images.

    abstract:BACKGROUND AND OBJECTIVE:Accurate segmentation of optic disc and cup from monocular color fundus images plays a significant role in the screening and diagnosis of glaucoma. Though optic cup is characterized by the drop in depth from the disc boundary, most existing methods segment the two structures separately and rely...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.06.004

    authors: Chakravarty A,Sivaswamy J

    更新日期:2017-08-01 00:00:00

  • Robust real time eye tracking for computer interface for disabled people.

    abstract::Gaze is a natural input for a Human Computer Interface (HCI) for disabled people, who have of course an acute need for a communication system. An efficient eye tracking procedure is presented providing a non-invasive method for real time detection of a subject eyes in a sequence of frames captured by low cost equipmen...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2009.03.010

    authors: De Santis A,Iacoviello D

    更新日期:2009-10-01 00:00:00

  • A Machine Learning decision-making tool for extubation in Intensive Care Unit patients.

    abstract:BACKGROUND AND OBJECTIVE:To increase the success rate of invasive mechanical ventilation weaning in critically ill patients using Machine Learning models capable of accurately predicting the outcome of programmed extubations. METHODS:The study population was adult patients admitted to the Intensive Care Unit. Target e...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2020.105869

    authors: Fabregat A,Magret M,Ferré JA,Vernet A,Guasch N,Rodríguez A,Gómez J,Bodí M

    更新日期:2020-11-24 00:00:00

  • A novel approach to speckle noise filtering based on Artificial Bee Colony algorithm: an ultrasound image application.

    abstract::In this study a novel approach based on 2D FIR filters is presented for denoising digital images. In this approach the filter coefficients of 2D FIR filters were optimized using the Artificial Bee Colony (ABC) algorithm. To obtain the best filter design, the filter coefficients were tested with different numbers (3×3,...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2013.05.009

    authors: Latifoğlu F

    更新日期:2013-09-01 00:00:00

  • Hospital-wide PACS with a digital image intensifier TV system.

    abstract::Tokyo Hitachi Hospital, Hitachi Ltd., has used a hospital-wide PACS for over 1 year. The system runs a 100 Mb/s optical fiber network over the whole hospital including wards and outpatient clinic rooms, with 11 image workstations. The network links digital imaging modalities such as X-CT, MRI, computed radiography (CR...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(94)90190-2

    authors: Okaniwa H,Tsuneyoshi H,Kabata S,Satoh K,Yokouchi H,Okabe T

    更新日期:1994-05-01 00:00:00

  • MARVIN: a medical research application framework based on open source software.

    abstract::This paper describes the open source framework MARVIN for rapid application development in the field of biomedical and clinical research. MARVIN applications consist of modules that can be plugged together in order to provide the functionality required for a specific experimental scenario. Application modules work on ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2008.04.007

    authors: Rudolph T,Puls M,Anderegg C,Ebert L,Broehan M,Rudin A,Kowal J

    更新日期:2008-08-01 00:00:00

  • Mathematical model of electrotonic interactions during excitation and repolarisation of myocardial tissue.

    abstract::A discrete model has been developed which reproduces the intercellular electrophysiological processes within a block of myocardial tissue. The behaviour of individual elements is introduced in the form of the digitised physiologic and premature action potentials which are comprehended as series of jumps between discre...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(91)90070-a

    authors: Malik M

    更新日期:1991-06-01 00:00:00

  • Virtual MR microscopy for unruptured aneurysm.

    abstract:PURPOSE:This study was performed to evaluate the usefulness of virtual magnetic resonance microscopy (VMRM) for the diagnosis of cerebral aneurysms. MATERIALS AND METHODS:We reviewed 11 patients with unruptured aneurysms confirmed by angiography or surgical therapy. We evaluated the ability of VMRM to represent aneury...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/s0169-2607(01)00142-0

    authors: Kobayashi N,Hosoya T,Adachi M,Haku T,Yamaguchi K

    更新日期:2001-07-01 00:00:00

  • Legal ethical and risk issues in telemedicine.

    abstract::This paper summarizes the main topics of discussion at a workshop hosted by the Centre for Law Ethics and Risk in Telemedicine at the 2nd International Conference on Advances in the Delivery of Care, held at the Institute of Health Sciences, City University, London from Wednesday 24 to Friday 26 March 1999. The worksh...

    journal_title:Computer methods and programs in biomedicine

    pub_type:

    doi:10.1016/s0169-2607(00)00142-5

    authors: Stanberry B

    更新日期:2001-03-01 00:00:00

  • Inter-lead correlation analysis for automated detection of cable reversals in 12/16-lead ECG.

    abstract:BACKGROUND AND OBJECTIVE:A crucial factor for proper electrocardiogram (ECG) interpretation is the correct electrode placement in standard 12-lead ECG and extended 16-lead ECG for accurate diagnosis of acute myocardial infarctions. In the context of optimal patient care, we present and evaluate a new method for automat...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2016.06.003

    authors: Jekova I,Krasteva V,Leber R,Schmid R,Twerenbold R,Müller C,Reichlin T,Abächerli R

    更新日期:2016-10-01 00:00:00

  • Fréchet PDF based Matched Filter Approach for Retinal Blood Vessels Segmentation.

    abstract:BACKGROUND AND OBJECTIVE:Retinal pathology diseases such as glaucoma, obesity, diabetes, hypertension etc. have deadliest impact on life of human being today. Retinal blood vessels consist of various significant information which are helpful in detection and treatment of these diseases. Therefore, it is essential to se...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2020.105490

    authors: Saroj SK,Kumar R,Singh NP

    更新日期:2020-10-01 00:00:00

  • Social network Analysis-based classifier (SNAc): A case study on time course gene expression data.

    abstract:BACKGROUND AND OBJECTIVES:Social Network Analysis is an attractive approach to model and analyze complex networks. In recent years, several bioinformatics related networks have been modeled and analyzed thoroughly using social network analysis. The objective of this study is to build a social network analysis based cla...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2017.06.015

    authors: Üçer S,Koçak Y,Ozyer T,Alhajj R

    更新日期:2017-10-01 00:00:00

  • New Doppler-based imaging method in echocardiography with applications in blood/tissue segmentation.

    abstract::A parametric model for the ultrasound signals from blood and tissue is developed and a new imaging method, knowledge-based imaging, is defined. This method utilizes the likelihood ratio function to classify blood and tissue signals. The method separates blood and tissue signals by the difference in movement patterns i...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2009.03.012

    authors: Hovda S,Rue H,Olstad B

    更新日期:2009-10-01 00:00:00

  • Classification-based quantitative analysis of stable isotope labeling by amino acids in cell culture (SILAC) data.

    abstract:BACKGROUND AND OBJECTIVE:Stable isotope labeling by amino acids in cell culture (SILAC) is a practical and powerful approach for quantitative proteomic analysis. A key advantage of SILAC is the ability to simultaneously detect the isotopically labeled peptides in a single instrument run and so guarantee relative quanti...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2016.09.017

    authors: Kim S,Carruthers N,Lee J,Chinni S,Stemmer P

    更新日期:2016-12-01 00:00:00

  • A simulation model for studies of intestine cell dynamics.

    abstract::A dynamic simulation model for the epithelial cell structures of the intestine has been developed. The model is based on hypotheses found in the literature. It is shown that basic cell dynamics can be reproduced by simulation experiments. The simulation program is designed so that model output comparable with experime...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(85)90067-7

    authors: Meinzer HP,Sandblad B

    更新日期:1985-11-01 00:00:00

  • A method for measuring and reporting manual data extraction reliability.

    abstract::As health care costs have risen dramatically, the use of clinical data to analyze the quality of health care provided has increased. Central to this analysis is the means by which the clinical data itself is obtained. The reliability and validity of the data must be established in order to insure credible use of the d...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/0169-2607(93)90063-q

    authors: Rozewski CM

    更新日期:1993-09-01 00:00:00

  • Machine vision application in animal trajectory tracking.

    abstract::This article was motivated by the doctors' demand to make a technical support in pathologies of gastrointestinal tract research [10], which would be based on machine vision tools. Proposed solution should be less expensive alternative to already existing RF (radio frequency) methods. The objective of whole experiment ...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2015.12.009

    authors: Koniar D,Hargaš L,Loncová Z,Duchoň F,Beňo P

    更新日期:2016-04-01 00:00:00

  • Computer tool to evaluate the cue reactivity of chemically dependent individuals.

    abstract:BACKGROUND AND OBJECTIVE:Anxiety is one of the major influences on the dropout of relapse and treatment of substance abuse treatment. Chemically dependent individuals need (CDI) to be aware of their emotional state in situations of risk during their treatment. Many patients do not agree with the diagnosis of the therap...

    journal_title:Computer methods and programs in biomedicine

    pub_type: 杂志文章

    doi:10.1016/j.cmpb.2016.11.014

    authors: Silva MLD,Frère AF,Oliveira HJQ,Martucci Neto H,Scardovelli TA

    更新日期:2017-03-01 00:00:00