Abstract:
:E1 enzymes activate ubiquitin or related proteins and pass them to E2 enzymes. A recent structure and associated biochemical studies (Huang et al., 2005) show how an E1 binds its cognate E2 and indicates that large, conformational changes will be an integral component of the E1 reaction cycle.
journal_name
Mol Celljournal_title
Molecular cellauthors
VanDemark AP,Hill CPdoi
10.1016/j.molcel.2005.02.004subject
Has Abstractpub_date
2005-02-18 00:00:00pages
474-5issue
4eissn
1097-2765issn
1097-4164pii
S1097-2765(05)01078-6journal_volume
17pub_type
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