Abstract：
INTRODUCTION:There are no conclusive data on the effectiveness of antidepressant drugs in the treatment of comorbid cases of alcohol dependence and depression. OBJECTIVES:To determine the effectiveness of venlafaxine on depression and on severity (need of treatment) of alcohol dependence and related problems. METHODS:Observational, open-label, multicenter, 24-week follow-up study. PATIENTS:90 outpatients with diagnosis of alcohol dependence and associated major depression disorder (DSMIV criteria). OUTCOMES MEASURES:the Hamilton Rating Scale for Depression (HAM-D17), European Addiction Severity Index (EuropASI) and Clinical Global Impression, severity and improvement subscales, (CGI-S and CGI-I). Evaluations were performed at baseline and at weeks 2, 4, 8 and 24. RESULTS:Mean age 44.94+/-9.74 years; 73.3 % man. HAM-D17 mean scores significantly decreased from baseline (24.85+/-5.94) to week 24 (5.976+/-4.68) and at each of the follow-up visits vs previous visit (p < 0.0005). Significant decreases from baseline to week 24 were obtained in four areas of EuropASI: medical status (2.12+/-2.45 to 1.07+/-1.68), alcohol use (5.29+/-2.24 to 3.04+/-2.35), family/ social relationships (3.68+/-2.36 to 1.71+/-2.06) and psychiatric status (5.61+/-1.81 to 2.67+/-2.03). Tolerance was excellent or good in 76.7% of the patients. CONCLUSIONS:Venlafaxine demonstrated to be effective in the treatment of depressive alcoholic patients. Furthermore, it seems to be useful to decrease the severity of problems related with the alcohol use.
journal_name
Actas Esp Psiquiatrjournal_title
Actas espanolas de psiquiatriaauthors
García-Portilla MP,Bascarán MT,Saiz PA,Mateos M,González-Quirós M,Pérez P,Avila JJ,Torres MA,Bombín B,Caso C,Marín R,Prieto R,Bobes Jsubject
Has Abstractpub_date
2005-01-01 00:00:00pages
41-5issue
1eissn
1139-9287issn
1578-2735pii
51110117journal_volume
33pub_type
临床试验,杂志文章,多中心研究abstract：INTRODUCTION:Due to the fact that various research studies have shown that drug users usually have a father with negative characteristics, it is convenient to investigate this phenomenon and take it into consideration in addict treatment efforts. METHODOLOGY:This is a qualitative study that explores the fatherly perce...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：INTRODUCTION:Satisfaction with life and psychological well-being have been extensively studied as measures of mental health, which has led to the development of two major traditions, the hedonic and eudaimonic. A difference has been found between subjective emotional well-being, which is often called psychological well...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2016-03-01 00:00:00
abstract：:Chronic feeling of emptiness (CFE) is con- sidered a diagnostic criteria in current psychiatric classifica- tions. However, no rating scale is still available for this phe- nomenological concept, which affects diagnostic reliability and the homogeneous use of the concept among clinicians. The aim of this study is to i...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2020-09-01 00:00:00
abstract：:Cyproheptadine is a drug with direct antimuscarinic, antihistaminic (H1) and antiseronergic (5HT2) effects. In spite of its use as an orexigenic agent in normal or anorectic subjects, little is known about its effect in affective, anxiety or psychotic disorders. We present the case of a 14-year patient beginning with ...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：:The Psychotic Symptom Rating Scales (PSYRATS) is a clinical assessment tool that focuses on the detailed measurement of delusions and hallucinations in patients with psychosis. The goal of this study was to examine the psychometric properties of the Portuguese version of the PSYRATS. A sample of 92 outpatients sufferi...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2017-03-01 00:00:00
abstract：INTRODUCTION:Psychiatrists use few symptoms when diagnosing depression. This study has aimed to know what symptoms are used by the psychiatrists to evaluate the severity of a depressive person compared to how they are evaluated when using a standardized instrument such as Hamilton's Rating Scale for Depression (HRSD-17...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To measure health related quality of life (HRQL) and social functioning in schizophrenic patients treated with olanzapine under regular clinical practice conditions. METHODS:Out-patients diagnosed of schizophrenia and beginning treatment with olanzapine, quetiapine, risperidone or typical oral antipsychotics...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:The economic crisis has negative effects on the population’s physical and mental health. Our objective has been to study the association between socioeconomic status and number of people demanding mental health services. METHODS:We performed a correlation analysis of administrative morbidity data (inciden...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2014-05-01 00:00:00
abstract：:Two psychiatric patients suffering from psychogenic polydipsia, hyponatremia and water intoxication were evaluated at emergency room. Both of them showed organic psychiatric disease which improve with medical treatment. We illustrated the physiological and clinical features of polydipsia, hyponatremia and water intoxi...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：INTRODUCTION:After the description of its involvement in amydalin lesions, there has been growing interest in the last decade on the neuropsychological examination of impaired emotional recognition in different diseases. This study aims to demonstrate the existence of emotional recognition impairment in a case of front...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:Infection with group A Streptococcus (StrepA) can cause post-infectious sequelae, including a spectrum of childhood-onset obsessive-compulsive (OCD) and tic disorders with autoimmune origin (PANDAS, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections). Until now, no sin...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:The Social Functioning Scale (SFS) was designed to evaluate social functioning essential to schizophrenic patients. Its length may be difficult to use in clinical practice. The objective of this study was to develop and validate a short version of the SFS. METHODS:Data from 445 patients with schizophrenia...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:One of the most typical clinical problems is the assessment of malingering in the field of forensic and penitentiary psychiatry. OBJECTIVE:The purpose of this research was to find associations between different personality types and psychometric response styles. MATERIAL AND METHODS. SUBJECTS:participant...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：INTRODUCTION:The high prevalence of bulimia nervosa among eating disorders and limited repertoire of assessment tools available for these disorders in Spanish have resulted in special interest regarding the adaptation of a specific instrument such as the Bulimia Test (BULIT). METHODOLOGY:A total of 119 outpatients, mo...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:Longitudinal studies are the only ones capable of responding to the question of whether cognitive deficits present in schizophrenia follow a stable course and establishing its evolutive relationship with other clinical symptoms of the disease. This article reviews a total of 30 studies published in patients with a fir...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章,评审
doi：
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:currently the treatment of mental illness by antidepressants is very frequent. Selective serotonin reuptake inhibitors are the most prescribed antidepressants worldwide and have been associated with alterations in accommodation or pupil. The objective of this study is to evaluate the effects of fluoxetine ...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2020-03-01 00:00:00
abstract：:The universal distribution of schizophrenia associated with the low fertility of these patients outlines the paradox: why doesn't diminish the prevalence of this dysfunction? A critical revision is made of the main hypotheses that have thought about to solve this question. Some theories have postulated a physiologic o...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-01 00:00:00
abstract：:The aim of this work is the review of the relationship between epilepsy and psychosis, considering the historic evolution, the classification, the treatment and the present situation of the ethiological aspects. Pointing up interictal and postictal psychosis due to their ethiological interest. ...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章,评审
doi：
更新日期：2001-03-01 00:00:00
abstract：:The aim of this paper is to analyze the influence and differential weight of some specific psychological variables on adolescent antisocial behavior. A sample of 1,851 adolescents (49.92 % men and 50.08 % women) from the Autonomous Community of Madrid was assessed. Several stepwise regression analyses were conducted, ...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：:In recent years, there has been considerable evidence on the phenomenon of intelligence quotient (IQ) gains over time with a gain rate of approximately three IQ points per decade. This phenomenon has been called the Flynn effect. This review article presents the evidence that supports this effect and discusses its imp...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章,评审
doi：
更新日期：2004-03-01 00:00:00
abstract：INTRODUCTION AND METHOD:The ESAP is a self-rating scale based on the panic attack with 0 to 3 scoring and the total score is obtained by adding the 14 scores- the highest score thus being 42. Forty patients were included for the study, and the were assessed at their first visit, after one week and after one month in th...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:The theory of mind (ToM) is a new concept which could be defined as the ability to make inferences on the intentions of others. This capacity has been used to explain childhood autism symptoms and recently an attempt has been made to refer it to schizophrenia. The authors aim to review the theory of mind concept, the ...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-01 00:00:00
abstract：AIM:This study has aimed to assess whether there are differences between immigrant and local psychiatric inpatients admitted to a general hospital in Spain in relation to diagnostic or treatment management. METHODS:We carried out a cohort study, with a sample of N=102 immigrant patients and N=102 local patients, match...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:In recent years, reports of attentional deficits in schizophrenic patients and in their biological relatives have rapidly increased, including an important effort to search for the endophenotypes in order to link specific genes to this illness. Posner et al. developed a test, the Attention Network Test (AN...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:The victims of terrorist attacks have a lower level of mental health than general population. However this effects has been only demonstrated in short term after the terrorist attack. METHODS:2998 people from 544 families who have suffered a terrorist attacks. General Health Questionnaire-28 (GHQ-28) as a p...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：INTRODUCTION:In spite of the frequent prophylactic use of lithium salts in affective disorders, few papers have been published about clinical outcome predictors in long-term follow-up. OBJECTIVE:To identify clinical predictors of long-term outcome in a sample of bipolar outpatients on lithium treatment. METHODS:An in...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：INTRODUCTION:Tourette's syndrome is a neurological disorder of genetic order that begins in childhood, being characterized by the presence of multiple phonic and motor tics. CLINICAL CASE:A male with previous dissociative and conversion psychopathology initiated motor and phonic tics in the adulthood in the context of...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：INTRODUCTION:Following the latest examination of the worldwide mental health situation, the World Health Organization has estimated that depression produces the greatest decrement in health compared with other chronic diseases, and has encouraged to all countries to increase investment and resources in this field. MET...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:The main objective of this study was to develop and validate a new olfactory measure that assesses the influence of olfaction on several emotional, behavioural, and cognitive issues: The Relational Scale of Olfaction (EROL). A secondary objective was to explore the relationship between the olfactory functi...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:The percentage of lack of adherence in schizophrenia is estimated in 50%. Non-compliance cause higher rates of relapses, rehospitalizations, suicide, homicide and violent behaviour among schizophrenic patients. The aim of this study was to find several factors related to adherence in schizophrenia. MATERIAL...
journal_title：Actas espanolas de psiquiatria
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
