Abstract:
:Pathogenesis of the development of sepsis is highly complex and has been the object of study for many years. The inflammatory phenomena underlying septic shock are described in this review, as well as the enzymes and genes involved in the cellular activation that precedes this condition. The most important molecular aspects are discussed, ranging from the cytokines involved and their respective transduction pathways to the cellular mechanisms related to accelerated catabolism and multi-organic failure.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
López-Bojórquez LN,Dehesa AZ,Reyes-Terán Gdoi
10.1016/j.arcmed.2004.07.006subject
Has Abstractpub_date
2004-11-01 00:00:00pages
465-79issue
6eissn
0188-4409issn
1873-5487pii
S0188-4409(04)00106-7journal_volume
35pub_type
杂志文章,评审abstract:BACKGROUND AND AIMS:Intestinal microbiota and soluble dietary fiber play an important role in intestinal microecology, which is closely related to gut motility. Regulating intestinal microecology comprised of fecal microbiota transplantation (FMT) or fiber supplementation is becoming a novel therapy for functional gast...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2016.06.005
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Metabolic syndrome (MetS) is a disorder that includes a cluster of several risk factors for the development of type 2 diabetes and cardiovascular disease. The R230C variant of the ABCA1 gene has been associated with low HDL-cholesterol in several studies, but its association with MetS in children re...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2015.07.008
更新日期:2015-08-01 00:00:00
abstract::Organic solvents cause injury to lipids of neuronal and glial membranes. A well known characteristic of workers exposed to thinner is optic neuropathy. We decided to look for neurophysiologic signs of visual damage in patients identified as thinner abusers. Pattern reversal visual evoked potentials was performed on 34...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND AND AIMS:As a newly discovered B-cell subset, PDCA-1(+) B cells have been shown to participate in the immune clearance of invading pathogens. The prominence of PDCA-1(+) B cell immunity in the pathogenesis of Helicobacter pylori infection prompted us to explore the potential role of this subset in gastric H....
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2016.04.003
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:It has been recently shown that oral administration of D002, a mixture of higher aliphatic primary alcohols isolated from beeswax, inhibits rat microsomal lipid peroxidation. This justified the present attempt to investigate whether D002 also exerts antioxidant effects in humans. METHODS:The effects of D002...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0188-4409(01)00315-0
更新日期:2001-09-01 00:00:00
abstract::In contrast to the prophylactic HPV vaccines that exhibit great promise in reducing the burden of cervical cancer, there is limited progress towards the development of immune therapeutic strategies that would help those women who are already infected with high-risk HPV and do not benefit from the current vaccines. The...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2009.07.003
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND AND AIMS:This study is concerned with the expressions of growth-associated protein-43 (GAP-43) mRNA and protein in the anterior horn of the spinal cord after brachial plexus injury. METHODS:Animals were killed 1, 7, 14 days after injury and were divided into three injury groups: group 1, right C(7) ventral ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2010.10.005
更新日期:2010-10-01 00:00:00
abstract::Two hundred fifty women with hirsutism were studied, with a mean age of 25.5 years (ranging from 13 to 38 years). The evolution of hirsutism varied from 3 months to 13 years, being minimal in 82 patients (33%), mild to 101 (40%), moderate in 56 (23%) and severe in the remaining 11 women (4%). Polycystic ovary syndrome...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:There is a need to assess whether human immunodeficiency virus (HIV)-infected patients are more likely than noninfected individuals to have any of the specific lipoprotein combination profiles identified as the best predictors of future cardiovascular disease in the general population. METHODS:One hundred f...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.06.012
更新日期:2008-01-01 00:00:00
abstract::Metabolic syndrome (MetS) should be considered a clinical entity when its different symptoms share a common etiology: obesity/insulin resistance as a result of a multi-organ dysfunction. The main interest in treating MetS as a clinical entity is that the addition of its components drastically increases the risk of ath...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2015.05.007
更新日期:2015-07-01 00:00:00
abstract::The amebicidal action of metronidazole is activated when the enzyme pyruvate:ferredoxin oxido-reductase transfers reducing equivalents to the nitro group of the drug. The enzyme is present in Entamoeba histolytica and other anaerobic parasites like Giardia and Trichomonas that lack mitochondria. The selectivity of the...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract:AIMS:To explore the effect of salvianolic acid B (Sal B) on regulation of SIRT3/FOXO1 signaling pathway in rats with non-alcoholic steatohepatitis (NASH). METHODS:Sixty Sprague Dawley (SD) rats were randomly divided into control, model and treatment groups. After 12 weeks of successful model establishment with high fa...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2017.11.016
更新日期:2017-08-01 00:00:00
abstract:BACKGROUNDS AND AIMS:Selenium nanoparticles (SeNPs) have been reported to exhibit an inhibitory effect on cancer cells. In the present study, we aimed to compare the in vitro and in vivo effects of SeNPs and folic acid surface-coated selenium nanoparticles (FA@SeNPs) on breast cancer. METHODS:FA@SeNPs and SeNPs were c...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2018.04.007
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Quinolone-induced mutagenesis in the Salmonella typhimurium hisG48 strains suggests that these antibiotics are oxygen free radical generators. The use of beta-carotene as antioxidant was evaluated as an alternative to reduce oxidative cell damage in patients who need therapy with nalidixic acid, norfloxacin,...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00046-1
更新日期:2000-03-01 00:00:00
abstract::We report a study on the DNA organization in Entamoeba histolytica using a ribosomal DNA probe. The rDNA genes were found forming mers which were separated in a typical ladder pattern by pulse field electrophoresis. DNA rosette structures were visualized through electron microscopy in DNA eluted from bands recognized ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::The effect of electric field stimulation for promoting axonal growth between sural to facial nerve grafts in cases of congenital permanent facial palsy associated with hemifacial microsomia was studied. For this purpose, a total of 17 patients with unilateral congenital permanent facial palsy associated with hemifacia...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Extended-spectrum β-lactamase (ESBLs) production is still the most frequent mechanism of resistance to cephalosporins in gram-negative bacteria. The aim of the study was to identify the types of ESBL-producing Enterobacteriaceae clinical isolates causing nosocomial infections in Mexico. METHODS:ESB...
journal_title:Archives of medical research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.arcmed.2011.02.004
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Selenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflammatory response. METHODS:This study consisted of 136 Iranian patients with cardiovascular disease (65 MetS-affected and 71 MetS un-affected individuals) in the selengene study. Expression o...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.05.005
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Because obesity masks the need for screening, there is no previous description of dyslipidemia in healthy normal-weight children. The aims of this study were a) to determine the prevalence of disorders in lipid profile among non-obese prepubertal children, and b) to establish its association with the family ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2006.06.003
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND AND AIMS:In this study, we aimed to investigate whether 1800 MHz frequency electromagnetic radiation (EMR) has an effect on bone healing. METHODS:A total of 30 Wistar albino rats were divided into two equal groups. Fractures were created in the right tibias of all rats; next, intramedullary fixations with K...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2014.01.006
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The design of efficient rabies control programs within a geographic area requires an appropriate knowledge of the local epidemiological cycles. In Latin America, there is a geographical overlap of the two main epidemiological cycles: (a) the terrestrial cycle, where the dog is the main terrestrial vector and...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-0128(98)00019-0
更新日期:1999-03-01 00:00:00
abstract::In order to establish the sensitivity and specificity of transesophageal stress echocardiography with dobutamine (TEE-dobutamine) in the early detection of myocardial ischemia we studied 30 consecutive patients from the Coronary Care Unit (CCU) of the Hospital de Cardiología, Centro Médico Nacional Siglo XXI. The resu...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Supplementation with n3 long-chain polyunsaturated fatty acids (n3-LCPUFA) appears to affect body weight, adipokines, and insulin resistance (IR) in obese individuals. However, it is unclear whether the effect on IR is independent of weight loss and if the same effect is observed in children. We und...
journal_title:Archives of medical research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.arcmed.2011.06.010
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Occult hepatitis B infection (OBI) is defined as a form of hepatitis in which, despite absence of detectable HBsAg, HBV-DNA is present in peripheral blood of patients. The main aim of this study was to determine an association between polymorphisms in +801 of CXCL12 (SDF-1α) and its serum level in OBI patien...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2010.07.001
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Cardiovascular (CV) risk factors are influenced by behavioral, cultural, and social factors, suggesting that acculturation plays a significant role in the emergency and growth of chronic disease. The objective of this study was to determine the relation between CV risk factors and the main components of accu...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.12.003
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:It remains unclear whether the activation of kappa-opioid receptors has strong hypotensive effects under hypertensive condition, and the underlying mechanisms have not yet been investigated. Therefore, the present study is designed to use spontaneously hypertensive rats (SHR) to investigate the effects of a ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.04.009
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to determine whether newborn birth weights were associated with insulin-like growth factor I (IGF-I), zinc, and leptin in preeclamptic and normotensive pregnancies. METHODS:This study was done cross-sectionally and included 15 women with moderate preeclampsia (PE group) and ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(01)00364-2
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Distal renal tubular acidosis (dRTA) is characterized by a reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis. Mutations in the SLC4A1 gene have been found to cause either autosomal dominant (AD) or autosomal recessive (AR)...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2012.05.001
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:The optimal treatment for patients with liver metastases from colorectal cancer is surgical resection. However, fewer than 10% of these patients will be amenable to this surgery. The aim of this study is to ascertain the natural history of a group of untreated patients, and to evaluate simultaneously in anot...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Proteolytic activity was measured in lysates of four axenic and five xenic cultures of different strains of pathogenic E. histolytica, and in five non-pathogenic strains ("E. dispar") growing in xenic culture. There was no significant difference in total proteolytic activity, using either gelatin or albumin as substra...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00