Abstract:
:The blood-brain barrier (BBB) is a physiologic barrier that protects the brain from toxic substances, including most of the chemotherapeutic agents used today. The BBB may be partly responsible for the poor efficacy of chemotherapy for malignant primary or metastatic brain tumors. A technique of osmotic modification of the BBB, known as BBB disruption (BBBD), is used to increase the delivery of chemotherapy to the brain. This article discusses the technique of osmotic opening of the BBB, the national BBBD program, the role of nurses in the care and management of patients undergoing BBBD treatment, outcomes of this technique with a variety of brain tumors, and the future directions of the BBBD program.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Haluska M,Anthony MLdoi
10.1188/04.CJON.263-267subject
Has Abstractpub_date
2004-06-01 00:00:00pages
263-7issue
3eissn
1092-1095issn
1538-067Xjournal_volume
8pub_type
杂志文章abstract::This article provides guidelines for the use of amifostine (Ethyol, Alza Pharmaceuticals, Palo Alto, CA, and U.S. Bioscience, Inc., West Conshohocken, PA), a pancytoprotective agent approved for reducing renal toxicity associated with cisplatin administration in patients with advanced ovarian or non-small cell lung ca...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::The focus of health care has moved toward prevention, and insurance companies are supporting preventive practices that enable their members to remain healthy. Many insurance companies have recorded healthy tips delivered by phone, employed case managers to assist patients in keeping physician appointments, created ded...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/16.CJON.566-567
更新日期:2016-10-01 00:00:00
abstract::S.R., a 65-year-old male with a history of prostate cancer, went to a cancer center in 2003. He had developed symptoms of bladder outlet obstruction in 1999 and was seen by a urologist. His baseline prostate-specific antigen (PSA) was 44 ng/ml. On physical examination, his prostate was enlarged, and a biopsy in Januar...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/06.CJON.565-566
更新日期:2006-10-01 00:00:00
abstract::Myelodysplastic syndromes (MDS) represent a group of clonal myeloid malignancies with variability in clinical presentation and disease trajectory, as well as prognosis and treatment recommendations (Kurtin & Demakos, 2010). MDS is considered to be a rare disease that is most common in adults older than age 70. The dis...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/12.CJON.S1.5-7
更新日期:2012-06-01 00:00:00
abstract::Malignant melanoma, the least common but most serious form of skin cancer, is increasing at a faster rate than any other form of cancer. Early diagnosis can lead to cures through surgery alone. Patients with deeper primary lesions (greater than 4 mm) or regional lymph node involvement have a high risk of relapse. High...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract::Today, I am writing for the first time as the new editor of the Clinical Journal of Oncology Nursing (CJON). It is my honor to assume this role from my colleague and mentor, Deborah K. Mayer, PhD, RN, AOCN, FAAN. For eight years, Deb served as the editor of one of the most widely read journals in oncology nursing, CJO...
journal_title:Clinical journal of oncology nursing
pub_type: 社论
doi:10.1188/15.CJON.387
更新日期:2015-08-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) ranks as the eighth most common cancer in the world. Although uncommon in North America, the incidence of HCC in the United States has increased by 70% since the 1980s (Yu, Yuan, Govindarajan, & Ross, 2000). The most frequent causes of malignant hepatic disease in the United States are m...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.647-652
更新日期:2003-11-01 00:00:00
abstract::Cast a wide net, and include internal and external customers in planning. Keep communicating about the results of the needs assessment and each plan as it emerges. Ask everyone involved for feedback. Employ clinicians with experience and solid credentials, and have a plan for measuring outcomes. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/05.CJON.373-374
更新日期:2005-06-01 00:00:00
abstract::Nurses play a crucial role in identifying bone metastases and managing clinical sequelae, such as pain. Understanding the metastatic process is necessary for delivering effective nursing care. Part I of this article described the pathophysiology and assessment. Part II will provide an overview of the nursing managemen...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:
更新日期:1997-04-01 00:00:00
abstract::In recent years, fatigue has been recognized as a prevalent and often debilitating symptom for patients with cancer. Despite the increased recognition of cancer-related fatigue (CRF), it often is not assessed adequately in the clinical setting. This article reports the results of a feasibility test to evaluate the uti...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,多中心研究
doi:10.1188/05.CJON.435-439
更新日期:2005-08-01 00:00:00
abstract::Communication skills are the cornerstone of the patient-provider relationship in cancer care. Lack of these skills can diminish patient disclosure, increase patient anxiety, and decrease satisfaction with care. The purpose of this article is to evaluate the literature regarding the efficacy and outcomes of communicati...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/05.CJON.305-312
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Chimeric antigen receptor (CAR) T-cell therapy program development has regulatory demands and unique operational processes that vary across settings. The infrastructure in which CAR T-cell therapy is implemented has implications for nursing education and competencies. OBJECTIVES:This article presents an ove...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/19.CJON.S1.20-26
更新日期:2019-04-01 00:00:00
abstract::This study was conducted to examine mood state and quality of life (QOL) in patients who had undergone a mastectomy. The study used a descriptive design and was conducted in outpatient oncology clinics in northeastern Iran. Using the Profile of Mood States and the Ferrans and Powers Quality of Life Index, the mood sta...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/12.CJON.E118-E122
更新日期:2012-06-01 00:00:00
abstract::Colorectal cancer screening aims to detect colorectal cancer at an early stage, when treatment is more likely to be curative. Lack of participation in such screening is a major issue in primary care practices, where nurse practitioners (NPs) often provide care. This study aimed to determine whether an educational inte...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.543-546
更新日期:2017-10-01 00:00:00
abstract::Therapeutic cancer vaccines that use attenuated vaccinia viruses as delivery vectors are undergoing clinical trials at dozens of sites internationally. Even in an attenuated form, these live viruses can cause severe illness if they are accidentally transmitted to immunocompromised people, pregnant women, or people wit...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/16.CJON.602-604
更新日期:2016-12-01 00:00:00
abstract::Selection of letters to be published is the decision of the editor. For acceptance, letters must be signed. A letter can appear anonymously if requested by the author. All letters are subject to editing. A letter that questions, criticizes, or responds to a previously published Clinical Journal of Oncology Nursing art...
journal_title:Clinical journal of oncology nursing
pub_type: 信件
doi:10.1188/14.CJON.14-15
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:With the advent of biosimilars into the U.S. healthcare market, knowledge deficits exist for nurses and patients regarding the regulatory approval process and key nursing considerations for each of these new medications. OBJECTIVES:This article provides essential clinical information for oncology nurses who...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.S1.21-26
更新日期:2018-10-01 00:00:00
abstract::Checkpoint inhibitors are a form of immunotherapy that have revolutionized treatment for malignant melanoma, resulting in longer survival and better disease control. Multiple autoimmune disorders can occur with the use of checkpoint inhibitors, including severe, potentially fatal neurologic complications. Although neu...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/19.CJON.355-358
更新日期:2019-08-01 00:00:00
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journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.41-48
更新日期:2011-02-01 00:00:00
abstract::eHealth applications will become a more prevalent operational component of the standard of care. They will continue to be reliable methods to expedite patient-provider communication, meet surveillance milestones, and provide timely symptom management. ...
journal_title:Clinical journal of oncology nursing
pub_type:
doi:10.1188/20.CJON.S1.3
更新日期:2020-06-01 00:00:00
abstract:CASE STUDY:Mrs. S is a 63-year-old retired teacher who returns to the office for breast cancer follow-up. She was diagnosed with intraductal carcinoma, and her treatment included a modified radial mastectomy followed by four cycles of doxorubicin and cyclophosphamide. Her tumor was estrogen receptor-positive, progester...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/07.628-630
更新日期:2007-10-01 00:00:00
abstract::Patients with cancer can experience several treatment-related symptoms, and conventional care focuses primarily on cure and survival without a holistic approach to disease. Subsequently, an increasing number of patients are accustomed to complementary modalities to improve well-being. Biofield therapies (BTs) are comp...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/14.CJON.568-576
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Legalization efforts in many states have heightened awareness of the medicinal uses of cannabis, and oncology nurses are more frequently caring for patients who have used or are using cannabis. Significant epidemiologic data on the prevalence of cannabis use in patients with cancer are not yet available, and...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/18.CJON.438-443
更新日期:2018-08-01 00:00:00
abstract::This article focuses on the symptoms of dyspnea and delirium, which can be extremely distressing to patients with cancer at the end of life. Oncology nurses are well suited to detect and treat these symptoms. . ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/16.CJON.244-246
更新日期:2016-06-01 00:00:00
abstract::The use of radiotherapy as a cancer treatment is common, so an appreciation of the biologic effects of radiation at a cellular level is essential to help nurses prepare their patients for the challenging journey ahead using appropriate lay language. The four Rs of radiotherapy (repair, redistribution, reoxygenation, a...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/13.CJON.412-417
更新日期:2013-08-01 00:00:00
abstract::Spirituality and religiosity have been defined by several governing bodies to mean everything from purpose in life, beliefs, faith, and hope, to transcendence with a higher being. The absence of uniformity regarding the components of spirituality and religiosity has created a barrier for professional caregivers in ide...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/12.CJON.E150-E155
更新日期:2012-08-01 00:00:00
abstract::Pancreatic cancer will account for about 6% of all cancer-related deaths in 2008. Patients often present with advanced disease, so treatment remains a challenge. This article will review the risk factors, pathology features, clinical symptoms, diagnosis and staging guidelines, treatment, and nursing implications of pa...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/08.CJON.735-741
更新日期:2008-10-01 00:00:00
abstract::Central venous access plays an important role in modern medical patient assessment and treatment. The use of central venous access devices has become routine in the oncology setting. Clinical oncology nurses need to know how the devices function, how to provide proper care, and how to manage potential side effects. Th...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/07.CJON.485-488
更新日期:2007-08-01 00:00:00
abstract::Patient safety is one of the most frequent terms used in health care today. Patients and their families are, first and foremost, focused on receiving effective and safe care, and oncology nurses strive to incorporate clinical evidence into day-to-day practice. This article provides a road map on how to incorporate eme...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/13.CJON.601-603
更新日期:2013-12-01 00:00:00
abstract::Intraperitoneal (IP) therapy is the administration of chemotherapy or biologic agents directly into the peritoneal cavity. A recent Gynecologic Oncology Group trial showed a survival advantage for women with advanced ovarian cancer and small residual disease after initial surgical staging and debulking who received IP...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,病人教育讲义,评审
doi:10.1188/07.CJON.211-216
更新日期:2007-04-01 00:00:00