Abstract:
:Checkpoint inhibitors are a form of immunotherapy that have revolutionized treatment for malignant melanoma, resulting in longer survival and better disease control. Multiple autoimmune disorders can occur with the use of checkpoint inhibitors, including severe, potentially fatal neurologic complications. Although neurologic complications are uncommon, their early recognition and treatment is required. The purpose of this article is to present information on neurologic complications of ipilimumab and nivolumab to inform nursing practice. Recommendations for evaluation and treatment of neurologic complications are reviewed.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Latchman J,Guastella A,Tofthagen Cdoi
10.1188/19.CJON.355-358subject
Has Abstractpub_date
2019-08-01 00:00:00pages
355-358issue
4eissn
1092-1095issn
1538-067Xjournal_volume
23pub_type
杂志文章abstract::Positron emission tomography (PET) scans use positrons, positively charged particles, to detect metabolic and chemical changes in the body. Although the clinical applications of this technology still are evolving, PET scans are being used to detect cancer and evaluate neurologic disorders, heart muscle function, and r...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/03.CJON.379-385
更新日期:2003-07-01 00:00:00
abstract::Oncology nurses have a critical role in mitigating the intense vulnerability, loss of control, and fear of the unknown that characterizes the experiences of patients with cancer and their family members. Reliably inquiring about the issues that are at the forefront for patients and their loved ones can encourage a dee...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/16.CJON.20-22
更新日期:2016-02-01 00:00:00
abstract::Over the past two decades, implanted ports have become widely used infusion therapy devices. Although these devices have revolutionized the care of patients with cancer and are used routinely to administer various treatments, complications still can occur. Nurses must be vigilant in identifying potential and actual po...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:
更新日期:1999-10-01 00:00:00
abstract::The oncology practice setting can be a highly emotional workplace because nurses provide care to many of the same patients and their families over time. Comparing and contrasting nurses from different clinical settings would provide insight into the more common themes of nursing grief and might give guidance on how to...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/09.CJON.625-627
更新日期:2009-12-01 00:00:00
abstract::In recent years, fatigue has been recognized as a prevalent and often debilitating symptom for patients with cancer. Despite the increased recognition of cancer-related fatigue (CRF), it often is not assessed adequately in the clinical setting. This article reports the results of a feasibility test to evaluate the uti...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,多中心研究
doi:10.1188/05.CJON.435-439
更新日期:2005-08-01 00:00:00
abstract::The challenges faced in my first year as a new oncology nurse included learning the beauty of small victories and understanding loss. Family and friends often mention how sad and hard this profession is. It is hard to explain how much I love this job to those who view it as somewhat depressing. The victories are the s...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/19.CJON.112
更新日期:2019-02-01 00:00:00
abstract::Central venous access plays an important role in modern medical patient assessment and treatment. The use of central venous access devices has become routine in the oncology setting. Clinical oncology nurses need to know how the devices function, how to provide proper care, and how to manage potential side effects. Th...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/07.CJON.485-488
更新日期:2007-08-01 00:00:00
abstract::Limited evidence-based standards of care exist in the management of irradiated skin; therefore, the development of a skin care protocol is necessary to improve patient outcomes. This article describes the use of the Iowa Model of Evidence-Based Practice to Promote Quality Care as a framework to identify and validate c...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.593-595
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Since the completion of the Human Genome Project in 2003, the implications of genetics and genomics for health and illness have become clearer. All nurses, at all levels and across all specialties, must have a basic understanding of genetics and genomics to provide appropriate care. . OBJECTIVES:This artic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.747-753
更新日期:2017-12-01 00:00:00
abstract::The purpose of this article is to review information relative to the administration, stability, and compatibility of paclitaxel (Taxol, Mead Johnson Oncology Products, Princeton, NJ). The unique formulation used to solubilize paclitaxel has led to an increased awareness of plasticizer-leaching issues, paclitaxel stabi...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Cancer-related pain is a major health problem because of its magnitude, the subjective nature of the pain experience, and the complexity of the disease, making it difficult to assess and control. When assessment is not performed, poor pain control can result. . OBJECTIVES:This article provides an overview o...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.S3.8-12
更新日期:2017-06-01 00:00:00
abstract::Navigation seeks to assess and address barriers that hinder a patient's access to care. With the success of the nurse navigation program at Penn Medicine's Abramson Cancer Center, leadership expanded navigation to neuro-oncology. The purpose of this article is to describe this population's unique needs and the effect ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.347-349
更新日期:2018-06-01 00:00:00
abstract::This study was conducted to examine mood state and quality of life (QOL) in patients who had undergone a mastectomy. The study used a descriptive design and was conducted in outpatient oncology clinics in northeastern Iran. Using the Profile of Mood States and the Ferrans and Powers Quality of Life Index, the mood sta...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/12.CJON.E118-E122
更新日期:2012-06-01 00:00:00
abstract::Most nurses agree that incorporating evidence into practice is necessary to provide quality care, but barriers such as time, resources, and knowledge often interfere with the actual implementation of practice change. Published practice guidelines are one source to direct practice; this article focuses on the use of th...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/07.CJON.817-821
更新日期:2007-12-01 00:00:00
abstract::Genetic testing for hereditary cancer syndromes is an integral component of oncology care. Various types of common errors that occur in the genetic testing process are presented in this article with actual clinical case examples and commentary. Genetic errors are expensive and may result in poor outcomes for the patie...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.673-676
更新日期:2017-12-01 00:00:00
abstract::When the Oncology Nursing Society (ONS) was almost exactly half its present age, in November 1994, a Boston Globe health columnist named Betsy Lehman was admitted to the Dana-Farber Cancer Institute in Boston, Massachusetts, to receive an investigational regimen for breast cancer. Her treatment ended in disaster. In o...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/15.CJON.155-156
更新日期:2015-04-01 00:00:00
abstract::The BCR-ABL inhibitor imatinib is standard first-line therapy for patients with chronic myeloid leukemia (CML) and has revolutionized treatment of the disease. However, resistance and intolerance to the agent have emerged as major clinical complications. Dasatinib is the first and only dual BCR-ABL/SRC family kinase i...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/09.CJON.316-323
更新日期:2009-06-01 00:00:00
abstract::More accurate patient identification is a Joint Commission National Patient Safety Goal. To decrease the possibility of patient misidentification during chemotherapy administration, nurses on the Bone Marrow Transplant Unit at the University of North Carolina-Chapel Hill instituted a bedside check and measured complia...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/09.CJON.716-717
更新日期:2009-12-01 00:00:00
abstract::Both of the articles reviewed here as well as the references, suggest that very little is actually known about the impact of many aspects of genetic testing. How decision are made about genetic testing in people who do not have cancer, how the results of testing are used used to guide care, and ultimately how people a...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::Oncology nurses and ancillary support personnel who work in oncology settings are at risk for exposure to antineoplastic drugs in their workplaces. A review of the literature reveals issues of environmental contamination and personal exposure. Although the United States has no formal regulations regarding hazardous dr...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/06.CJON.473-477
更新日期:2006-08-01 00:00:00
abstract::Increased understanding of the molecular composition of breast cancer tumors has led to the development of targeted anticancer agents. Novel therapies directed against human epidermal growth factor receptor 2 (HER2) in breast cancer have been developed. One such agent, trastuzumab emtansine (T-DM1), is an antibody dru...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/13.CJON.E58-E62
更新日期:2013-10-01 00:00:00
abstract::This article describes family history assessment for colorectal cancer in three outpatient gastroenterology units and examines gastroenterology unit nurses' knowledge and attitudes about family history assessments. Eighty-eight colonoscopy records were surveyed, and 16 RNs were interviewed. The medical record document...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.E75-E82
更新日期:2011-10-01 00:00:00
abstract::Many hospitalized patients with cancer are malnourished. Some become critically ill and experience delayed wound healing, loss of muscle strength, and reduced infection fighting ability as a consequence of the loss of nutritional reserves. Complications of critical illness may cause interruption in normal gastrointest...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/02.CJON.287-289
更新日期:2002-09-01 00:00:00
abstract::Nearly all patients experience some degree of urinary irritative or obstructive symptoms following brachytherapy for definitive treatment of early-stage prostate cancer. The American Urological Association (AUA) Symptom Index is a tool developed to measure urinary function and can be incorporated into postoperative nu...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:In the management of lung cancer, molecular profiling of the tumor is pivotal to defining a personalized treatment plan and is recommended for each patient. OBJECTIVES:The purpose of this article is to provide an update on genomic testing in lung cancer and the associated targeted treatment options. In addi...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.648-656
更新日期:2020-12-01 00:00:00
abstract::I recently earned my baccalaureate nursing degree and passed the nursing boards. Soon, I hope to practice as a clinical oncology nurse. As a new RN, I frequently reflect on the people and situations that have influenced my growth so far as a nurse. I have been fortunate to work with many clinical mentors who have been...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.120
更新日期:2018-02-01 00:00:00
abstract::Homelessness is a national problem that is worsening. Some challenges the homeless face-lack of shelter, food, health care, support, and opportunities-are well known. Cancer, an unrecognized problem among the homeless, is a leading cause of their deaths. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/18.CJON.676-679
更新日期:2018-12-01 00:00:00
abstract::Aromatase inhibitors (AIs) have become integral to the treatment of women with breast cancer and are the treatment of choice in postmenopausal women who have tumors that are estrogen receptor positive. The depletion of estrogen seen with AI therapy is significant and translates to beneficial tumor effect but has a neg...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/09.CJON.E18-E29
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:With increasing support for the integration of palliative care and standard oncology, communication training programs are needed to teach oncology nurses and other providers about palliative care communication. OBJECTIVES:This study reports on the outcomes of COMFORTTM SM Communication for Oncology Nurses, ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.E1-E6
更新日期:2020-02-01 00:00:00
abstract::S.R., a 65-year-old male with a history of prostate cancer, went to a cancer center in 2003. He had developed symptoms of bladder outlet obstruction in 1999 and was seen by a urologist. His baseline prostate-specific antigen (PSA) was 44 ng/ml. On physical examination, his prostate was enlarged, and a biopsy in Januar...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/06.CJON.565-566
更新日期:2006-10-01 00:00:00