Evidence-based research for intraperitoneal chemotherapy in epithelial ovarian cancer.

Abstract:

:Intraperitoneal (IP) therapy is the administration of chemotherapy or biologic agents directly into the peritoneal cavity. A recent Gynecologic Oncology Group trial showed a survival advantage for women with advanced ovarian cancer and small residual disease after initial surgical staging and debulking who received IP therapy when compared to the standard IV regimen. The results prompted a National Cancer Institute announcement recommending the use of IP therapy in women who meet the criteria. This article describes the rationale for and underlying principles of IP therapy and summarizes the results of the three main clinical trials that led to the recommendation for incorporation of IP therapy into initial treatment of epithelial ovarian cancer.

journal_name

Clin J Oncol Nurs

authors

Almadrones L

doi

10.1188/07.CJON.211-216

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

211-6

issue

2

eissn

1092-1095

issn

1538-067X

pii

71L00M354T387TN9

journal_volume

11

pub_type

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