Abstract:
BACKGROUND:Pretransplantation chemotherapy and side effects of transplantation can cause reduced oral intake, contributing to malnutrition. OBJECTIVES:The aim was to evaluate the current evidence comparing enteral nutrition (EN) to parenteral nutrition in the adult hematopoietic stem cell transplantation (HSCT) population. METHODS:A systematic review was conducted in PubMed/MEDLINE®, CINAHL® Plus With Full Text (EBSCO), and Cochrane Library and produced 238 articles. Four articles met inclusion criteria. FINDINGS:Three studies were observational; one was a randomized trial that ended prematurely. Outcomes included tolerance of EN, incidences of graft-versus-host disease (GVHD), rate of infection, and mortality. This limited information suggests that EN may have a protective mechanism against advanced stages of GVHD and contribute to decreased risk of infection-related death.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Reese MK,Hewlings Sdoi
10.1188/19.CJON.173-179subject
Has Abstractpub_date
2019-04-01 00:00:00pages
173-179issue
2eissn
1092-1095issn
1538-067Xjournal_volume
23pub_type
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