Enteral Versus Parenteral Nutrition: Use in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation.

Abstract:

BACKGROUND:Pretransplantation chemotherapy and side effects of transplantation can cause reduced oral intake, contributing to malnutrition. OBJECTIVES:The aim was to evaluate the current evidence comparing enteral nutrition (EN) to parenteral nutrition in the adult hematopoietic stem cell transplantation (HSCT) population. METHODS:A systematic review was conducted in PubMed/MEDLINE®, CINAHL® Plus With Full Text (EBSCO), and Cochrane Library and produced 238 articles. Four articles met inclusion criteria. FINDINGS:Three studies were observational; one was a randomized trial that ended prematurely. Outcomes included tolerance of EN, incidences of graft-versus-host disease (GVHD), rate of infection, and mortality. This limited information suggests that EN may have a protective mechanism against advanced stages of GVHD and contribute to decreased risk of infection-related death.

journal_name

Clin J Oncol Nurs

authors

Reese MK,Hewlings S

doi

10.1188/19.CJON.173-179

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

173-179

issue

2

eissn

1092-1095

issn

1538-067X

journal_volume

23

pub_type

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