Abstract:
:The purpose of this article is to review information relative to the administration, stability, and compatibility of paclitaxel (Taxol, Mead Johnson Oncology Products, Princeton, NJ). The unique formulation used to solubilize paclitaxel has led to an increased awareness of plasticizer-leaching issues, paclitaxel stability in solution, and paclitaxel compatibility with other medications. Particularly with longer paclitaxel infusion schedules (greater than 48 hours), both drug stability in solution and pump apparatus congruence require careful consideration to minimize plasticizer-leaching problems and to ensure optimum drug delivery. Despite knowledge of the physical compatibility of paclitaxel with numerous drugs, a paucity of research has documented the specifics of paclitaxel's chemical compatibility with other medications.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Boyle DA,Goldspiel BRsubject
Has Abstractpub_date
1998-10-01 00:00:00pages
141-5issue
4eissn
1092-1095issn
1538-067Xjournal_volume
2pub_type
杂志文章,评审abstract:BACKGROUND:Cervical cancer is the fourth most common cancer among women worldwide. Most diagnoses occur in developing countries where cases are detected in later stages with poorer prognoses. Cervical cancer is a preventable disease; however, most women in developing and resource-limited countries do not have the acces...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/16.CJON.79-83
更新日期:2016-02-01 00:00:00
abstract::eHealth applications will become a more prevalent operational component of the standard of care. They will continue to be reliable methods to expedite patient-provider communication, meet surveillance milestones, and provide timely symptom management. ...
journal_title:Clinical journal of oncology nursing
pub_type:
doi:10.1188/20.CJON.S1.3
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Targeted therapy and immunotherapy agents for advanced melanoma are associated with novel toxicities. Melanoma clinical nurse consultants (CNCs) provide multifaceted clinical care. . OBJECTIVES:The objective was to evaluate the type of support, excluding clinic and inpatient care, provided by CNCs for patie...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.E93-E98
更新日期:2017-08-01 00:00:00
abstract::Colorectal cancer screening aims to detect colorectal cancer at an early stage, when treatment is more likely to be curative. Lack of participation in such screening is a major issue in primary care practices, where nurse practitioners (NPs) often provide care. This study aimed to determine whether an educational inte...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.543-546
更新日期:2017-10-01 00:00:00
abstract::Limited evidence-based standards of care exist in the management of irradiated skin; therefore, the development of a skin care protocol is necessary to improve patient outcomes. This article describes the use of the Iowa Model of Evidence-Based Practice to Promote Quality Care as a framework to identify and validate c...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.593-595
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Nurses and other healthcare workers are at risk for adverse health consequences from occupational exposure to hazardous drugs. OBJECTIVES:An evidence-based program for nurses was implemented to improve safe handling practices and reduce exposure to hazardous drugs. METHODS:A quasiexperimental design was us...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.73-78
更新日期:2017-02-01 00:00:00
abstract::Smoking cessation remains a high priority in oncology nursing practice. That priority gained additional visibility in 2014 when the Oncology Nursing Society (ONS) endorsed the tobacco position statement of the International Society of Nurses in Cancer Care, emphasizing the potential for nurses to reduce adult and yout...
journal_title:Clinical journal of oncology nursing
pub_type: 社论
doi:10.1188/18.CJON.243-244
更新日期:2018-06-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) is the fifth most common cause of all malignancies and causes approximately one million deaths each year. Surgical liver resection is the only cure for HCC; however, few patients are eligible to undergo this procedure. Hepatic artery chemoembolization (HACE) is a technique that delivers ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/05.CJON.69-75
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Many patients with incurable cancer do not accurately understand their prognosis, which can lead to aggressive and, often, futile treatment. Improved prognostic awareness can help patients to appropriately de-escalate aggressive treatment sooner in an illness trajectory. OBJECTIVES:The purpose of this artic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/16.CJON.385-390
更新日期:2016-08-01 00:00:00
abstract::Providing care for patients with cancer places caregivers at risk for experiencing elevated levels of stress. Caregivers of patients with brain tumors may be at increased risk because of the multifaceted needs of this patient population. As such, the authors sought to determine caregiver preferences toward various typ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/07.CJON.723-727
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Transitions from acute clinical care to the outpatient setting can be daunting. Clear explanations of discharge instructions from nurses and assessment of the patient's understanding can have a positive impact. OBJECTIVES:The purpose of this study was to assess the effect of an education intervention on nur...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/19.CJON.288-294
更新日期:2019-06-01 00:00:00
abstract::The World Health Organization describes sexuality as a "central aspect of being human throughout life and encompasses sex, gender identities and roles, sexual orientation, eroticism, pleasure, intimacy, and reproduction. Sexuality is influenced by the interaction of biological, psychological, social, economic, politic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.S1.53-65
更新日期:2011-08-01 00:00:00
abstract::Studies have documented the efficacy of cancer treatments available, specifically for patients with prostate or breast cancer, but few articles have compared prostate or breast cancer recommendations from the patient's perspective. In this article, the authors compare and contrast published clinical recommendations fo...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/14.CJON.667-673
更新日期:2014-12-01 00:00:00
abstract::Oral health is often not a priority during cancer treatment; however, patients with cancer are at increased risk for oral complications during and after treatment. This article focuses on the importance of oral health care before, during, and after cancer treatment using the head, eyes, ears, nose, oral cavity, and th...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/15.CJON.615-619
更新日期:2015-10-01 00:00:00
abstract::Taxane-induced peripheral neuropathy (TIPN) affects a number of patients with breast cancer. To properly manage these patients, nurses must be able to identify and assess TIPN, as well as educate patients on TIPN as a side effect of taxane therapy. This article provides practical suggestions regarding how nurses can i...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/13.CJON.S1.22-34
更新日期:2013-02-01 00:00:00
abstract::To assess the effectiveness of multidimensional rehabilitation programs (MDRPs) in terms of maintaining or improving the physical and psychosocial well-being of adult cancer survivors. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.722-723
更新日期:2014-12-01 00:00:00
abstract::Homelessness is a national problem that is worsening. Some challenges the homeless face-lack of shelter, food, health care, support, and opportunities-are well known. Cancer, an unrecognized problem among the homeless, is a leading cause of their deaths. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/18.CJON.676-679
更新日期:2018-12-01 00:00:00
abstract::The blood-brain barrier (BBB) is a physiologic barrier that protects the brain from toxic substances, including most of the chemotherapeutic agents used today. The BBB may be partly responsible for the poor efficacy of chemotherapy for malignant primary or metastatic brain tumors. A technique of osmotic modification o...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/04.CJON.263-267
更新日期:2004-06-01 00:00:00
abstract::You may have heard of the National Cancer Moonshot Initiative led by former Vice President Joe Biden. It has brought together many people through a task force, blue ribbon panel, and many public forums to discuss how best "to dramatically accelerate efforts to prevent, diagnose, and treat cancer - to achieve a decade'...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.141-142
更新日期:2017-04-01 00:00:00
abstract::Older patients with cancer who may be more susceptible than younger patients to the myelosuppressive effects of chemotherapy undergo dose delays and reductions that can compromise treatment outcomes. Incidence of neutropenic complications and suboptimal chemotherapy delivery can be reduced with prophylactic colony-sti...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1188/10.CJON.81-86
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Since the completion of the Human Genome Project in 2003, the implications of genetics and genomics for health and illness have become clearer. All nurses, at all levels and across all specialties, must have a basic understanding of genetics and genomics to provide appropriate care. . OBJECTIVES:This artic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.747-753
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:With increasing support for the integration of palliative care and standard oncology, communication training programs are needed to teach oncology nurses and other providers about palliative care communication. OBJECTIVES:This study reports on the outcomes of COMFORTTM SM Communication for Oncology Nurses, ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.E1-E6
更新日期:2020-02-01 00:00:00
abstract::Increased understanding of the molecular composition of breast cancer tumors has led to the development of targeted anticancer agents. Novel therapies directed against human epidermal growth factor receptor 2 (HER2) in breast cancer have been developed. One such agent, trastuzumab emtansine (T-DM1), is an antibody dru...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/13.CJON.E58-E62
更新日期:2013-10-01 00:00:00
abstract::Neuroendocrine tumors (NETs), including gastroenteropancreatic NETs, or GEP-NETs, are heterogenous tumors that arise from diffuse neuroendocrine cells and other organs, such as the lung, ovary, and thyroid. Lutetium Lu 177 dotatate (Lutathera®) is a newly approved targeted therapy for patients with advanced GEP-NETs. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.565-568
更新日期:2018-10-01 00:00:00
abstract::Spirituality and religiosity have been defined by several governing bodies to mean everything from purpose in life, beliefs, faith, and hope, to transcendence with a higher being. The absence of uniformity regarding the components of spirituality and religiosity has created a barrier for professional caregivers in ide...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/12.CJON.E150-E155
更新日期:2012-08-01 00:00:00
abstract::Aromatase inhibitors (AIs) have become integral to the treatment of women with breast cancer and are the treatment of choice in postmenopausal women who have tumors that are estrogen receptor positive. The depletion of estrogen seen with AI therapy is significant and translates to beneficial tumor effect but has a neg...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/09.CJON.E18-E29
更新日期:2009-10-01 00:00:00
abstract::S.R., a 65-year-old male with a history of prostate cancer, went to a cancer center in 2003. He had developed symptoms of bladder outlet obstruction in 1999 and was seen by a urologist. His baseline prostate-specific antigen (PSA) was 44 ng/ml. On physical examination, his prostate was enlarged, and a biopsy in Januar...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/06.CJON.565-566
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Caregiver burden associated with caring for women with ovarian cancer has received limited focus. However, these patients often have complex needs, requiring a high level of care at home and imposing substantial burdens on caregivers. OBJECTIVES:This pilot study assessed the level of caregiver burden experi...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/16.CJON.169-173
更新日期:2016-04-01 00:00:00
abstract::Family caregiving often is associated with multiple rewards, yet the diversity and intensity of caregiving roles also can result in caregiver strain and burden. Using interventions to reduce the strain and burden on caregivers of patients with cancer is an important role nurses play. This article is a critical review ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/08.CJON.507-516
更新日期:2008-06-01 00:00:00
abstract::Advances in breast brachytherapy techniques have led to the development of new approaches for treatment of patients with early-stage breast cancer. This article reviews the indications, clinical utility, and nursing interventions for the Mammosite Radiation Therapy System (Proxima Therapeutics, Alpharetta, GA) and INT...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.324-328
更新日期:2003-05-01 00:00:00