Abstract:
BACKGROUND:With the advent of biosimilars into the U.S. healthcare market, knowledge deficits exist for nurses and patients regarding the regulatory approval process and key nursing considerations for each of these new medications. OBJECTIVES:This article provides essential clinical information for oncology nurses who are directly involved in patient care who will be administering U.S. Food and Drug Administration (FDA)-approved biosimilars for oncologic use. Oncology nurses must be informed on their therapeutic uses, mechanisms of action, and administration considerations. METHODS:An overview of biosimilars in the United States is given, and each FDA-approved oncology biosimilar medication is described in detail. FINDINGS:Oncology biosimilars are safe and effective treatment options that may increase patient access, decrease healthcare costs through competition, and improve the lives of patients with certain malignancies. Nurses are in key roles in patient care to foster the transition from previously patented, branded, and expensive medications to biosimilars that can achieve the same desired effects for a lower cost.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Zack Edoi
10.1188/18.CJON.S1.21-26subject
Has Abstractpub_date
2018-10-01 00:00:00pages
21-26issue
5eissn
1092-1095issn
1538-067Xjournal_volume
22pub_type
杂志文章abstract:BACKGROUND:Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype that disproportionately affects women who are African American, younger, or carriers of the BRCA1 gene. No targeted treatments exist for the disease, which has distinct features and presents unique challenges to patients who have bee...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/15.CJON.62-67
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:The use of theory can provide structure for understanding the dynamics of adherence to oral agents for cancer (OACs) and facilitate the development of strategies for patient assessment and care planning related to oral adherence. OBJECTIVES:The focus of this article is to identify common theories pertinent ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/15.S1.CJON.31-35
更新日期:2015-06-01 00:00:00
abstract::Unexpected cardiac issues at an early age inspired me to return to school to pursue a career in nursing. While in school, a close relationship with a family member facing a terminal cancer diagnosis gave me insight into the importance of listening as a tool for keeping patients safe and delivering the most appropriate...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.13-14
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:A cancer diagnosis is a serious stressor that is associated with anxiety, depression, sleep disorders, and inability to fulfill daily routines. Many pharmacologic and nonpharmacologic options are available to help patients with cancer manage anxiety. OBJECTIVES:This randomized, controlled trial examined the...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,随机对照试验
doi:10.1188/18.CJON.203-210
更新日期:2018-04-01 00:00:00
abstract::Cancer-related lymphedema is a progressive and chronic syndrome of abnormal swelling and multiple symptoms resulting from cancer treatment. Even with modern medical advances, lymphedema remains a major health problem affecting thousands of cancer survivors. To provide healthcare professionals with evidence-based clini...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.S3.68-79
更新日期:2014-01-01 00:00:00
abstract::In recent years, fatigue has been recognized as a prevalent and often debilitating symptom for patients with cancer. Despite the increased recognition of cancer-related fatigue (CRF), it often is not assessed adequately in the clinical setting. This article reports the results of a feasibility test to evaluate the uti...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,多中心研究
doi:10.1188/05.CJON.435-439
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Cervical cancer is the fourth most common cancer among women worldwide. Most diagnoses occur in developing countries where cases are detected in later stages with poorer prognoses. Cervical cancer is a preventable disease; however, most women in developing and resource-limited countries do not have the acces...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/16.CJON.79-83
更新日期:2016-02-01 00:00:00
abstract::Patients with cancer often use massage therapy as an adjunct treatment. Oncology nurses can be advocates for patients seeking massage therapy by educating them to be informed consumers of massage therapy. They can stress that patients with cancer use massage therapists who have graduated from accredited programs, meet...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/02.CJON.52-54
更新日期:2002-01-01 00:00:00
abstract::Cancer survivors face many challenges as a result of their cancer diagnosis and treatment, most importantly the maintenance of physical well-being. Nurses and other health professionals strive to address the needs of cancer survivors, including providing appropriate health-promotion information for a physically active...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.683-686
更新日期:2011-12-01 00:00:00
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journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.423-427
更新日期:2017-08-01 00:00:00
abstract::An intervention with the Scored Patient-Generated Subjective Global Assessment was implemented at a community cancer center to identify patients with sarcoma at risk for malnutrition. This population usually is not considered to be at nutritional risk because of young age and the site of diagnosis; however, 60% of pat...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/10.CJON.375-377
更新日期:2010-06-01 00:00:00
abstract::Advances in breast brachytherapy techniques have led to the development of new approaches for treatment of patients with early-stage breast cancer. This article reviews the indications, clinical utility, and nursing interventions for the Mammosite Radiation Therapy System (Proxima Therapeutics, Alpharetta, GA) and INT...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.324-328
更新日期:2003-05-01 00:00:00
abstract::IBC is a rare clinical occurrence. Signs and symptoms include erythema and edema of the skin. Diagnosis is made by skin biopsy. Treatment for this aggressive form of breast cancer is multimodal, including chemotherapy, surgery, radiation therapy, and hormonal therapy. Advances in treatment continue to improve prognosi...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:
更新日期:2001-07-01 00:00:00
abstract::Current evidence for the management of radiation skin toxicities demonstrates equivocal outcomes using a variety of interventions, leaving substantial gaps in knowledge. Skin toxicities can lead to treatment delays, infection, pain, and increased costs for the patient. Patients with head and neck cancers receiving che...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/12.CJON.278-285
更新日期:2012-06-01 00:00:00
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journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/07.CJON.485-488
更新日期:2007-08-01 00:00:00
abstract::Positron emission tomography (PET) scans use positrons, positively charged particles, to detect metabolic and chemical changes in the body. Although the clinical applications of this technology still are evolving, PET scans are being used to detect cancer and evaluate neurologic disorders, heart muscle function, and r...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/03.CJON.379-385
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:In the environment of an infectious pandemic, vaccines are a primary public health strategy to prevent the spread of disease. With the COVID-19 pandemic, there is heightened interest in safe and effective vaccines and their use in the context of clinical oncology practice. OBJECTIVES:This article provides f...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/21.CJON.76-84
更新日期:2021-02-01 00:00:00
abstract::Gastric cancer is difficult to diagnose at an early stage. Signs and symptoms of the disease often only occur when advanced or metastatic disease is present. A very small number of gastric cancers are hereditary. The mutation to the E-cadherin gene has high penetrance and confers a lifetime risk of gastric cancer of 8...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/02.CJON.161-162
更新日期:2002-05-01 00:00:00
abstract::Most nurses agree that incorporating evidence into practice is necessary to provide quality care, but barriers such as time, resources, and knowledge often interfere with the actual implementation of practice change. Published practice guidelines are one source to direct practice; this article focuses on the use of th...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/07.CJON.817-821
更新日期:2007-12-01 00:00:00
abstract::The National Database of Nursing Quality Indicators (NDNQI, 2020) defines a patient fall as an unplanned descent to the floor with or without injury. A fall occurs in 30%-50% of hospitalized patients with cancer in the United States (Jatoi, 2017). According to the Joint Commission (2015), the average cost of each fall...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.448-450
更新日期:2020-08-01 00:00:00
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journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/16.CJON.566-567
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:With increasing support for the integration of palliative care and standard oncology, communication training programs are needed to teach oncology nurses and other providers about palliative care communication. OBJECTIVES:This study reports on the outcomes of COMFORTTM SM Communication for Oncology Nurses, ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.E1-E6
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Exercise, light physical activity, and decreased sedentary time all have been associated with health benefits following cancer diagnoses. Commercially available wearable activity trackers may help patients monitor and self-manage their behaviors to achieve these benefits. OBJECTIVES:This article highlights ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/16.CJON.606-610
更新日期:2016-12-01 00:00:00
abstract::Temsirolimus is a targeted therapy that inhibits mammalian target of rapamycin (mTOR), a central regulator of tumor cell responses to growth stimuli. Temsirolimus has a broad anticancer activity profile that impacts tumor cell growth, proliferation, and survival through its specific inhibition of mTOR. In a randomized...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/08.CJON.639-646
更新日期:2008-08-01 00:00:00
abstract::Ribavirin is used in the treatment of respiratory syncytial virus (RSV) in high-risk patients, including patients who have undergone hematopoietic stem cell transplantation, to reduce mortality from RSV pneumonia. It is classified as a hazardous drug with potential for carcinogenicity and teratogenicity. Very few rece...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.E93-E96
更新日期:2014-10-01 00:00:00
abstract::Radioimmunotherapy is a new cancer therapy that combines the cytotoxicity of radiation with the tumor-specific targeting of monoclonal antibodies. Yttrium 90 (Y-90) ibritumomab tiuxetan (Zevalin, IDEC Pharmaceuticals Corporation, San Diego, CA) is indicated for the treatment of patients with relapsed or refractory low...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/04.CJON.31-34
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Depression in patients with cancer negatively influences physical symptoms, treatment success, coping, and quality of life (QOL), and is associated with increased mortality. OBJECTIVES:This study investigated the prevalence of depression and explored fatigue, QOL, and pain that is associated with depression...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/19.CJON.423-429
更新日期:2019-08-01 00:00:00
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journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.711
更新日期:2020-12-01 00:00:00
abstract::Spirituality and religiosity have been defined by several governing bodies to mean everything from purpose in life, beliefs, faith, and hope, to transcendence with a higher being. The absence of uniformity regarding the components of spirituality and religiosity has created a barrier for professional caregivers in ide...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/12.CJON.E150-E155
更新日期:2012-08-01 00:00:00
abstract::Neuroendocrine tumors (NETs), including gastroenteropancreatic NETs, or GEP-NETs, are heterogenous tumors that arise from diffuse neuroendocrine cells and other organs, such as the lung, ovary, and thyroid. Lutetium Lu 177 dotatate (Lutathera®) is a newly approved targeted therapy for patients with advanced GEP-NETs. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.565-568
更新日期:2018-10-01 00:00:00