Abstract:
:S.R., a 65-year-old male with a history of prostate cancer, went to a cancer center in 2003. He had developed symptoms of bladder outlet obstruction in 1999 and was seen by a urologist. His baseline prostate-specific antigen (PSA) was 44 ng/ml. On physical examination, his prostate was enlarged, and a biopsy in January 2000 revealed adenocarcinoma with a Gleason score of 8. A metastatic workup, including a bone scan and a computed tomography scan of the abdomen and pelvis (CT A/P), was negative for evidence of metastatic disease. S.R. received conformal external beam radiation, and the luteinizing hormone-releasing hormone agonist leuprolide acetate was initiated. Following treatment, his PSA nadired to 0.2 ng/ml, and he did well until 2002, when his PSA started to rise. A reevaluation CT A/P revealed enlarged retroperitoneal and pelvic lymph nodes, and a bone scan was positive for metastatic disease. He underwent a bilateral orchiectomy in November 2002.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Doyle-Lindrud Sdoi
10.1188/06.CJON.565-566subject
Has Abstractpub_date
2006-10-01 00:00:00pages
565-6issue
5eissn
1092-1095issn
1538-067Xjournal_volume
10pub_type
杂志文章,评审abstract:BACKGROUND:Since the completion of the Human Genome Project in 2003, the implications of genetics and genomics for health and illness have become clearer. All nurses, at all levels and across all specialties, must have a basic understanding of genetics and genomics to provide appropriate care. . OBJECTIVES:This artic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.747-753
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Depression in patients with cancer negatively influences physical symptoms, treatment success, coping, and quality of life (QOL), and is associated with increased mortality. OBJECTIVES:This study investigated the prevalence of depression and explored fatigue, QOL, and pain that is associated with depression...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/19.CJON.423-429
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Although guidelines for the safe handling of hazardous drugs (HDs) have existed for several decades, they have not been enforceable by state or federal agencies. USP <800>, the latest chapter issued by the U.S. Pharmacopeial Convention, expands on existing guidelines and provides detailed information on comp...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.179-187
更新日期:2017-04-01 00:00:00
abstract::The oncology practice setting can be a highly emotional workplace because nurses provide care to many of the same patients and their families over time. Comparing and contrasting nurses from different clinical settings would provide insight into the more common themes of nursing grief and might give guidance on how to...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/09.CJON.625-627
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Oncologic emergencies associated with multiple myeloma include myelosuppression (anemia, neutropenia, and thrombocytopenia), bone-related emergencies, and acute renal failure. . OBJECTIVES:This article reviews the pathophysiology of these multiple myeloma-associated oncology emergencies and provides a fram...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.S5.60-76
更新日期:2017-10-01 00:00:00
abstract::Pancreatic neuroendocrine tumors (pNETs), an uncommon finding, are distinct from pancreatic carcinomas. When pNETs are unresectable and progressive, visceral pain often presents and is challenging to treat. Opioids commonly used for pain control are difficult to implement in this setting because of adverse side effect...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.218-220
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Sipuleucel-T, an autologous cellular immunotherapy, is approved for the treatment of certain patients with metastatic castration-resistant prostate cancer (mCRPC). Sipuleucel-T is the first personalized treatment for prostate cancer to be manufactured using the immune system of each individual patient. Patie...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/15.CJON.297-303
更新日期:2015-06-01 00:00:00
abstract::Patients with cancer receiving therapy may face a variety of complicated and stressful symptoms. Oncology nurses can advocate for patients by performing their roles as educators and comanagers of cancer-related side effects. In addition, symptom-focused education provided by oncology nurses can enable patients to admi...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.253-258
更新日期:2011-06-01 00:00:00
abstract::The use of advanced practice professionals (APPs) has been established in oncology care. APPs are frequently the most readily available ordering provider for care guidance when it becomes evident that a patient with cancer is failing. The purpose of the current preliminary descriptive project was to determine the best...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.301-306
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Early childhood dental caries (dental cavities) is an infectious process. The development of oral problems during cancer care results in pain, fever, and delay in treatment. . OBJECTIVES:The objective of this project was to integrate preventive oral care into pediatric oncology care. . METHODS:This proje...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.611-616
更新日期:2017-10-01 00:00:00
abstract::In recent years, fatigue has been recognized as a prevalent and often debilitating symptom for patients with cancer. Despite the increased recognition of cancer-related fatigue (CRF), it often is not assessed adequately in the clinical setting. This article reports the results of a feasibility test to evaluate the uti...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,多中心研究
doi:10.1188/05.CJON.435-439
更新日期:2005-08-01 00:00:00
abstract::The World Health Organization describes sexuality as a "central aspect of being human throughout life and encompasses sex, gender identities and roles, sexual orientation, eroticism, pleasure, intimacy, and reproduction. Sexuality is influenced by the interaction of biological, psychological, social, economic, politic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.S1.53-65
更新日期:2011-08-01 00:00:00
abstract::Distress is commonly experienced by people with cancer. The National Comprehensive Cancer Network (NCCN) developed a guideline for screening and managing distress in 1999 and has updated the guideline on an annual basis ever since. Using the five-phase framework for translational research, this article summarizes rese...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.S1.26-30
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Nurses and other healthcare workers are at risk for adverse health consequences from occupational exposure to hazardous drugs. OBJECTIVES:An evidence-based program for nurses was implemented to improve safe handling practices and reduce exposure to hazardous drugs. METHODS:A quasiexperimental design was us...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.73-78
更新日期:2017-02-01 00:00:00
abstract::Adult patients with cancer in the acute care setting face numerous potential complications related to malignancy. Risk for development of venous thromboembolism (VTE) is among the most critical of adverse outcomes for this patient population, ultimately leading to increased morbidity and mortality rates. Nurses must b...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.18-03AP
更新日期:2014-06-01 00:00:00
abstract::Older patients with cancer who may be more susceptible than younger patients to the myelosuppressive effects of chemotherapy undergo dose delays and reductions that can compromise treatment outcomes. Incidence of neutropenic complications and suboptimal chemotherapy delivery can be reduced with prophylactic colony-sti...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1188/10.CJON.81-86
更新日期:2010-02-01 00:00:00
abstract::Current evidence for the management of radiation skin toxicities demonstrates equivocal outcomes using a variety of interventions, leaving substantial gaps in knowledge. Skin toxicities can lead to treatment delays, infection, pain, and increased costs for the patient. Patients with head and neck cancers receiving che...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/12.CJON.278-285
更新日期:2012-06-01 00:00:00
abstract::The 40th anniversary of the Oncology Nursing Society is the perfect time to reflect on the role that advanced practitioners in oncology (APOs) play in the care of patients with cancer. APOs have become an important part of cancer care. This group of professionals practicing in various settings includes physician assis...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/15.CJON.226-227
更新日期:2015-04-01 00:00:00
abstract::Because of the Human Genome Project, nurses increasingly must understand how genetics impact health and treatment decisions. Although the sequencing of the human genome was crucial, the next step is advancing the understanding of genomics, interpreting genetic information, and using that information to improve health ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.330-332
更新日期:2011-06-01 00:00:00
abstract::Anemia is a decrease in circulating red blood cells that contributes to a complex group of symptoms. Anemia may be present in more than half of all patients with cancer but often is assessed, documented, prevented, and treated inadequately. Individuals with cancer are living longer, and the number of cancer treatment ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/07.CJON.349-359
更新日期:2007-06-01 00:00:00
abstract::The neutropenic diet historically has been a mainstay in oncology practice, with many providers continuing to adhere tightly to the diet for patients with neutropenia. However, clinically sound evidence remains limited and weak and does not support the diet as a foundation for policy and practice. Therefore, two quest...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/14.CJON.239-241
更新日期:2014-04-01 00:00:00
abstract::Leptomeningeal metastases typically have been a rare complication of systemic cancers. The incidence is increasing for cancers of the breast and lung, primarily because of more effective treatment modalities and longer survival. Presentation consists of multiple symptoms related to areas in the central nervous system,...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.151-155
更新日期:2003-03-01 00:00:00
abstract::First-line treatment for chronic myelogenous leukemia (CML) is imatinib, but some patients do not respond or develop resistance to the drug, leading to suboptimal responses. Dasatinib and nilotinib are approved second-line compounds for patients experiencing imatinib failure. In a prospective comparison of dasatinib w...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/09.CJON.537-542
更新日期:2009-10-01 00:00:00
abstract::Radioimmunotherapy is a new cancer therapy that combines the cytotoxicity of radiation with the tumor-specific targeting of monoclonal antibodies. Yttrium 90 (Y-90) ibritumomab tiuxetan (Zevalin, IDEC Pharmaceuticals Corporation, San Diego, CA) is indicated for the treatment of patients with relapsed or refractory low...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/04.CJON.31-34
更新日期:2004-02-01 00:00:00
abstract::Both of the articles reviewed here as well as the references, suggest that very little is actually known about the impact of many aspects of genetic testing. How decision are made about genetic testing in people who do not have cancer, how the results of testing are used used to guide care, and ultimately how people a...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::When the Oncology Nursing Society (ONS) was almost exactly half its present age, in November 1994, a Boston Globe health columnist named Betsy Lehman was admitted to the Dana-Farber Cancer Institute in Boston, Massachusetts, to receive an investigational regimen for breast cancer. Her treatment ended in disaster. In o...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/15.CJON.155-156
更新日期:2015-04-01 00:00:00
abstract::Screening for illness should be an evidence-based activity. Screening tests are useful only if they reduce mortality or morbidity. Therefore, healthcare professionals must know how to evaluate research about screening tests to be sure that, in fact, the tests actually accomplish their goals. Tests that generate many f...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/06.CJON.73-76
更新日期:2006-02-01 00:00:00
abstract::Advances in breast brachytherapy techniques have led to the development of new approaches for treatment of patients with early-stage breast cancer. This article reviews the indications, clinical utility, and nursing interventions for the Mammosite Radiation Therapy System (Proxima Therapeutics, Alpharetta, GA) and INT...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.324-328
更新日期:2003-05-01 00:00:00
abstract::Positron emission tomography (PET) scans use positrons, positively charged particles, to detect metabolic and chemical changes in the body. Although the clinical applications of this technology still are evolving, PET scans are being used to detect cancer and evaluate neurologic disorders, heart muscle function, and r...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/03.CJON.379-385
更新日期:2003-07-01 00:00:00
abstract::This article provides guidelines for the use of amifostine (Ethyol, Alza Pharmaceuticals, Palo Alto, CA, and U.S. Bioscience, Inc., West Conshohocken, PA), a pancytoprotective agent approved for reducing renal toxicity associated with cisplatin administration in patients with advanced ovarian or non-small cell lung ca...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00