Implications of androgen-deprivation therapy in patients with prostate cancer: A case study.

Abstract:

:S.R., a 65-year-old male with a history of prostate cancer, went to a cancer center in 2003. He had developed symptoms of bladder outlet obstruction in 1999 and was seen by a urologist. His baseline prostate-specific antigen (PSA) was 44 ng/ml. On physical examination, his prostate was enlarged, and a biopsy in January 2000 revealed adenocarcinoma with a Gleason score of 8. A metastatic workup, including a bone scan and a computed tomography scan of the abdomen and pelvis (CT A/P), was negative for evidence of metastatic disease. S.R. received conformal external beam radiation, and the luteinizing hormone-releasing hormone agonist leuprolide acetate was initiated. Following treatment, his PSA nadired to 0.2 ng/ml, and he did well until 2002, when his PSA started to rise. A reevaluation CT A/P revealed enlarged retroperitoneal and pelvic lymph nodes, and a bone scan was positive for metastatic disease. He underwent a bilateral orchiectomy in November 2002.

journal_name

Clin J Oncol Nurs

authors

Doyle-Lindrud S

doi

10.1188/06.CJON.565-566

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

565-6

issue

5

eissn

1092-1095

issn

1538-067X

journal_volume

10

pub_type

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