Abstract:
:The rapid development of new drugs, therapies, and devices has created a dramatic increase in the number of trials needed to properly evaluate them. The majority of patients treated today, many of whom could be eligible for participation in these studies, are seen in community hospitals and medical practices that are not affiliated with an academic medical center. Thus, there is a demonstrable need for physicians in private practice to enlist as investigators in these trials. This article is intended to encourage those physicians by describing the need and providing the rationale for their participation. It covers basic requirements for participating in clinical trials and outlines ethical, regulatory, financial, and other logistical issues of importance for the potential investigator and provides an algorithm for selecting a study for participation. Finally, the appendices review basic elements of study design and statistical principles, which may be of interest to a potential investigator.
journal_name
Circulationjournal_title
Circulationauthors
Lader EW,Cannon CP,Ohman EM,Newby LK,Sulmasy DP,Barst RJ,Fair JM,Flather M,Freedman JE,Frye RL,Hand MM,Jesse RL,Van de Werf F,Costa F,American College of Cardiology Foundation.doi
10.1161/01.CIR.0000128702.16441.75subject
Has Abstractpub_date
2004-06-01 00:00:00pages
2672-9issue
21eissn
0009-7322issn
1524-4539pii
109/21/2672journal_volume
109pub_type
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