Preclinical neurophysiological signs of parkinsonism in occupational manganese exposure.

Abstract:

:To study the effects from low level exposure to manganese, 30 men at steel smelting works and 60 nonexposed reference subjects, were neurophysiologically examined using: (i) Electroencephalogram (EEG), Event related auditory evoked potential (AEP/P300), Brain stem auditory evoked potential (BAEP) and diadochokinesometry. No group differences concerning EEG or BAEP were found. Diadochokinesis was slower and there was a tendency towards prolonged P300 latency in the exposed group as compared to the referents. These effects may be interpreted as early (subclinical) signs of disturbances of the same type as parkinsonism.

journal_name

Neurotoxicology

journal_title

Neurotoxicology

authors

Wennberg A,Hagman M,Johansson L

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

271-4

issue

1

eissn

0161-813X

issn

1872-9711

journal_volume

13

pub_type

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