Abstract:
:Copper (Cu) deficiency is associated with changes in arterial pressure. The effect depends of the age of initiation of the copper-deficient diet. Copper deficiency started at a young age causes hypotension. When initiated in older or adult animals, copper deficiency can cause hypertension. A case-control study was carried out to investigate the effect of administrating 5 mg Cu/d in 60 subjects, both genders, with mild stable hypertension, pharmacologically untreated (treated group) and compared with 60 hypertensives (control group) who were matched by gender, age, body weight, smoking habits, calories, fat and salt intake (NaCl), and physical activity. Hypertension was diagnosed when the blood pressure was > 150/95 mm Hg. Mean age, mean corporal weight and risk factors were similar in both groups. The results suggested the existence of a marginal deficiency of the trace element in 62% of subjects and demonstrated that Cu decreases systolic (r = -0.963) and diastolic (r = -0.981) blood pressures in treated group (p < 0.05). Control patients did not show significant changes in their arterial pressures. These findings indicate a functional alteration in human blood pressure regulation during mild copper depletion and suggest that Cu could be used in the treatment of stable moderate arterial hypertension. Further investigation is needed to determine the extent of this influence.
journal_name
Arch Latinoam Nutrjournal_title
Archivos latinoamericanos de nutricionauthors
Alarcón OM,Guerrero Y,Ramírez de Fernández M,D'Jesús I,Burguera M,Burguera JL,Di Bernardo MLsubject
Has Abstractpub_date
2003-09-01 00:00:00pages
271-6issue
3eissn
0004-0622issn
2309-5806journal_volume
53pub_type
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章,评审
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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更新日期:1979-09-01 00:00:00
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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更新日期:1996-06-01 00:00:00
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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更新日期:1997-12-01 00:00:00
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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更新日期:1987-09-01 00:00:00
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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更新日期:1993-06-01 00:00:00
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journal_title:Archivos latinoamericanos de nutricion
pub_type: 杂志文章
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journal_title:Archivos latinoamericanos de nutricion
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