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The urge for an AIDS vaccine: perspectives from a developing country.

Abstract：

:AIDS is inexorably involving all parts of the country and all strata of society, with 10% of the urban and 3% of the rural population infected with HIV. It is increasingly a disease of women and children. The major cofactors for transmission are also sexually transmitted. For most developing countries, in spite of all education efforts, the "silent epidemic" of AIDS continues. AIDS is known but not understood; counselling modifies behavior in only 10-20% of at-risk persons. Under optimal conditions, HIV discordant females have seroconversion rates of 4.7% per year and pregnancy rates of 10.4% per year. The recent political unrest in Zaire and Haiti will further enhance the spread of AIDS in these countries. Despite these difficult periods, the work can and must continue. After all, during our 10th year of collaboration with a Haitian private research group, the Haitian government and Cornell University, Haiti has known seven different political rulers. Finally, I want to make a pledge on behalf of the millions of people who face a certain death from HIV infection and AIDS and who will never make the front page of any newspaper. For these people, you can make a difference. You must give us the tools to carry on this fight. The clinical trials must be done where they are most needed: the developing countries. Vaccines represent the only viable alternative despite the recognized obstacles of viral heterogeneity, immunogenicity, and delivery.

journal_name

AIDS Res Hum Retroviruses

journal_title

AIDS research and human retroviruses

authors

Pape JW,Deschamps MM,Verdier RI,Jean S,Desvarieux M,Taverne G,Gelin C,Hyppolite PR,Denize J,Mellon R

doi

10.1089/aid.1992.8.1535

keywords:

["Acquired Immunodeficiency Syndrome--prevention and control","Americas","Caribbean","Delivery Of Health Care","Developing Countries","Diseases","Economic Factors","Epidemics","Haiti","Health","Health Services","Hiv Infections","Immunization","Latin America","Medicine","Needs","North America","Preventive Medicine","Primary Health Care","Vaccination","Vaccines","Viral Diseases"]

subject

Has Abstract,Author List Incomplete

pub_date

1992-08-01 00:00:00

pages

1535-7

issue

eissn

0889-2229

issn

1931-8405

journal_volume

pub_type

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The urge for an AIDS vaccine: perspectives from a developing country.