Exercise-induced human coronary collateral function: quantitative assessment during acute coronary occlusions.

Abstract:

:In 50 patients undergoing percutaneous transluminal coronary angioplasty because of chronic angina pectoris, a collateral flow index (CFI) was determined at the start and the end of two 1-min coronary occlusions, randomly accompanied by a resting state or a 3-min dynamic handgrip exercise (DHE). CFI expressing collateral flow relative to normal antegrade flow was determined by simultaneous coronary occlusive pressure, mean aortic pressure and central venous pressure measurements. When comparing CFI without and with DHE at the start as well as at the end of balloon occlusions, a significant increase was observed with DHE (overall p < 0.0001); start: 0.18 +/- 0.12 vs. 0.22 +/- 0.13, respectively (p = 0.01); end of occlusion: 0.21 +/- 0.14 vs. 0.25 +/- 0.14, respectively (p = 0.007).

journal_name

Cardiology

journal_title

Cardiology

authors

Pohl T,Wustmann K,Zbinden S,Windecker S,Mehta H,Meier B,Seiler C

doi

10.1159/000073039

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

53-60

issue

2

eissn

0008-6312

issn

1421-9751

pii

73039

journal_volume

100

pub_type

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