Abstract：
:A triphasic oral contraceptive containing ethinyl estradiol and gestodene was used by 1933 women for up to 36 cycles in order to evaluate contraceptive efficacy, general tolerance and cycle control. Altogether, 30,763 treatment cycles were recorded. Two pregnancies were seen, both of them classified as user failure. The rates of spotting and breakthrough bleeding fell below the rates of the pre-treatment cycle after the first three months of treatment. Adverse events were mostly minor with breast tension and headaches the most common complaints. After the first three cycles, the incidence of most complaints was the same as or even lower than in the pre-treatment cycle. Blood pressure and body weight remained practically unchanged. The trial preparation provided reliable contraception with good general tolerance and cycle control when taken for up to three years.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Weber-Diehl F,Unger R,Lachnit Udoi
10.1016/0010-7824(92)90128-gsubject
Has Abstractpub_date
1992-07-01 00:00:00pages
19-27issue
1eissn
0010-7824issn
1879-0518pii
0010-7824(92)90128-Gjournal_volume
46pub_type
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