The effect of ritanserin on treatment-resistant neuroleptic induced akathisia: case reports.

abstract：:1. The carboxyl terminus of the amyloid precursor protein (APP) has several identified regions that may potentially contribute to the pathogenic effects of Alzheimer's disease (AD). To examine these effects, the authors iodinated a short synthetic peptide corresponding to amino acids 679-687 of APP695. They also produ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Daly J,Lahiri DK,Kotwal GJ

更新日期：1999-07-01 00:00:00

abstract：:Sustained attention deficits are proposed to be both state and trait indicators of bipolar disorder. The nature of these deficits and their association with medication and symptoms is not clear yet. The aim of this study was to investigate the impairments in various components of sustained attention task in euthymic a...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Bora E,Vahip S,Akdeniz F

更新日期：2006-08-30 00:00:00

abstract：:1. The possible influence of haloperidol and its metabolite plasma levels on clinical outcome in schizophrenic patients was evaluated. 2. 18 schizophrenic inpatients diagnosed according to DSM III, were treated with conventional haloperidol p.o. for four weeks. 3. Plasma levels of haloperidol and its reduced metabolit...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Altamura C,Mauri M,Cavallaro R,Colacurcio F,Gorni A,Bareggi S

更新日期：1988-01-01 00:00:00

abstract：:The interaction between genes and environment seems to be relevant for the development of Attention Deficit/Hyperactivity Disorder (ADHD), one of the most prevalent childhood psychiatric diseases. The occurrence of ADHD is typically associated with poor academic performance, probably reflecting learning difficulties a...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Pamplona FA,Pandolfo P,Savoldi R,Prediger RD,Takahashi RN

更新日期：2009-10-01 00:00:00

abstract：:Correlation between specific binding potencies "in vitro" of several benzodiazepines and activities in SCR-habituation test is very satisfactory. As the SCR-habituation test might be considered as an elementary model of anxiety state, the test is suggested to be used as an intermediate psychopharmacological tool befor...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Marcy R,Quermonne MA,Raoul J,Nammathao B,Smida A

更新日期：1985-01-01 00:00:00

abstract：:Several lines of evidence suggest that the human 5-HT(7) receptor may be involved in the pharmacodynamics of risperidone and may influence clinical response of the drug. A pharmocogenetics study of this receptor may therefore be useful in developing individualized therapy. But few studies about it have been done. In t...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Wei Z,Wang L,Xuan J,Che R,Du J,Qin S,Xing Y,Gu B,Yang L,Li H,Li J,Feng G,He L,Xing Q

更新日期：2009-04-30 00:00:00

abstract：:1. Twenty-two patients hospitalized for treatment of depression were treated under conditions simulating those of home treatment. 2. Full doses of nortriptyline, from 100 to 150 mg/day, were started after baseline observations were made. 3. Two patients were dropped from the study, one for orthostatic hypotension, one...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Peabody C,Van Norman J,Hollister L,Warner D

更新日期：1991-01-01 00:00:00

abstract：:Lithium is one of the most commonly used drugs for the treatment of bipolar disorder. To prescribe lithium appropriately to patients, predictors of response to this drug were explored, and several genetic markers are considered to be good candidates. We previously reported a significant association between genetic var...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Masui T,Hashimoto R,Kusumi I,Suzuki K,Tanaka T,Nakagawa S,Suzuki T,Iwata N,Ozaki N,Kato T,Takeda M,Kunugi H,Koyama T

更新日期：2008-01-01 00:00:00

abstract：:Over a decade of work by Flynn and colleagues has delineated a network of limbic circuits which function to modulate the expression of predatory aggression and defence in the cat, and aspects of this work are reviewed. In particular, Flynn's work revealed a circuit involving the basomedial amygdala which functions to ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Adamec RE,Stark-Adamec CI

更新日期：1983-01-01 00:00:00

abstract：:1. Studies on the metabolism of the tricyclic antidepressant trimipramine (TMP) in the rat are described. 2. Twenty metabolites of TMP were isolated from rat urine after enzymatic hydrolysis and their structures were determined by a gas chromatographic-mass spectrometric (GC-MS) method. 3. Twelve TMP metabolites were ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Hussain MS,Coutts RT,Baker GB,Micetich RG,Daneshtalab M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Suicidal behavior has been widely accepted as familial. Its transmission cannot be explained by the transmission of psychiatric disorder alone and seems to be partly explained by the transmission of impulsive-aggressive behavior. Studies in laboratory animal have shown that mice lacking NOS1 manifest signifi...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Cui H,Supriyanto I,Asano M,Ueno Y,Nagasaki Y,Nishiguchi N,Shirakawa O,Hishimoto A

更新日期：2010-08-16 00:00:00

abstract：:The present study compared retrospectively in a clinical non-experimental setting the efficacy of buprenorphine (BUP) in different subgroups of dually diagnosed and non-dually diagnosed opioid-dependent patients: all the subjects included in the study showed severe long-lasting heroin addiction and 68.4% were affected...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Gerra G,Leonardi C,D'Amore A,Strepparola G,Fagetti R,Assi C,Zaimovic A,Lucchini A

更新日期：2006-03-01 00:00:00

abstract：:Although several recent studies have suggested that neuroinflammation plays a role in depression, both medication and neuroinflammatory preventive strategies have been poorly investigated. Recent studies have indicated that preconditioning with lipopolysaccharide (LPS) reduces the damage that occurs following ischemic...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Koga M,Toda H,Kinoshita M,Asai F,Nagamine M,Shimizu K,Kobayashi Y,Morimoto Y,Yoshino A

更新日期：2020-12-20 00:00:00

abstract：:Neuronal apoptosis and impaired hippocampal neurogenesis are major players in cognitive/memory dysfunctions including Alzheimer's disease (AD). Interferon beta (IFNβ) is a cytokine with anti-apoptotic and neuroprotective properties on the central nervous system (CNS) cells which specifically affects neural progenitor ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Chavoshinezhad S,Mohseni Kouchesfahani H,Ahmadiani A,Dargahi L

更新日期：2019-08-30 00:00:00

abstract：:Adolescence is a developmental period marked by robust neural alterations and heightened vulnerability to stress, a factor that is highly associated with increased risk for emotional processing deficits, such as anxiety. Stress-induced upregulation of the dynorphin/kappa opioid receptor (DYN/KOP) system is thought to,...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Varlinskaya EI,Johnson JM,Przybysz KR,Deak T,Diaz MR

更新日期：2020-03-02 00:00:00

abstract：:Suriclone, a new psychotherapeutic agent chemically unrelated to benzodiazepines or phenothiazines was assessed in a single-blind dose-ranging study to determine its efficacy and safety in out-patients with generalized anxiety disorder. Suriclone was an effective anxiolytic drug at a dose range between 1.2 mg. and 3.6...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lapierre YD,Oyewumi KL

更新日期：1983-01-01 00:00:00

abstract：:Inconsistent results have been reported with respect to cardiac autonomic function in major depression. The aim of our study was to investigate autonomic function in various branches of the autonomic nervous system in order to better understand parasympathetic and sympathetic modulation in the disease. We investigated...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Schumann A,Andrack C,Bär KJ

更新日期：2017-10-03 00:00:00

abstract：:1. The acute effects of some of typical and atypical antipsychotic drugs on the dopamine release and metabolism in the dorsal striatum of freely moving rats were studied using transcerebral microdialysis technique. 2. Classical neuroleptic drugs haloperidol (0.05, 0.1 and 0.2 mg/kg), thioproperazine (0.1, 0.2 and 0.4 ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Rayevsky KS,Gainetdinov RR,Grekhova TV,Sotnikova TD

更新日期：1995-12-01 00:00:00

abstract：:Accumulating evidence supports the hypothesis that modulation of glutamatergic system via NMDA receptors and mGlu5 receptors might be an effective antidepressant therapy. However, clinical application of NMDA and mGlu5 antagonists in the therapy of depression is still an open question. In the present study we investig...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Pałucha-Poniewiera A,Pilc A

更新日期：2012-10-01 00:00:00

abstract：:Postpartum depression occurs in 10-15% of mothers. Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that plays a role in neuroplasticity. We hypothesized that the concentration of BDNF is related to reproduction and childbirth, and that women with postpartum depression show alteration in BDNF level. A...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lee Y,Kim KH,Lee BH,Kim YK

更新日期：2021-01-11 00:00:00

abstract：:Alterations of antioxidant enzyme activities have been described in a number of psychiatric disorders including major depression. Subsequently, the present study examined the effects of different types of antidepressants (desipramine, imipramine, maprotiline and mirtazapine) in different concentrations (10(-5), 10(-6)...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Schmidt AJ,Heiser P,Hemmeter UM,Krieg JC,Vedder H

更新日期：2008-08-01 00:00:00

abstract：RATIONALE:The endocannabinoid system has been implicated in the neurobiological mechanism underlying drug addiction, especially the primary rewarding dopamine-dependent processes. Therefore, endocannabinoid receptor antagonists, such as the CB1 cannabinoid antagonist rimonabant, have been proposed as candidates for pre...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Marinho EA,Oliveira-Lima AJ,Santos R,Hollais AW,Baldaia MA,Wuo-Silva R,Yokoyama TS,Takatsu-Coleman AL,Patti CL,Longo BM,Berro LF,Frussa-Filho R

更新日期：2015-04-03 00:00:00

abstract：:Emotion regulation by means of cognitive reappraisal has been widely studied with functional magnetic resonance imaging (fMRI). To date, several meta-analyses of studies using cognitive reappraisal tasks in healthy volunteers have been carried out, but no meta-analyses have yet been performed on the fMRI data of clini...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Picó-Pérez M,Radua J,Steward T,Menchón JM,Soriano-Mas C

更新日期：2017-10-03 00:00:00

abstract：:1. The investigations in biological factors of childrens' behaviour disorder are becoming increasingly important as their significance in clinical management is being recognized with more precision and clarity. 2. One of such electroencephalographic investigations is finding of some delay or defect in chronological ma...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Singh AN

更新日期：1982-01-01 00:00:00

abstract：:Associations between attention deficit hyperactivity disorder (ADHD) and genetic polymorphisms in the dopamine receptors, transporter and metabolizing enzymes have been reported in different ethnic groups. Gene variants may affect disease outcome by acting synergistically or antagonistically and thus their combined ef...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Das M,Das Bhowmik A,Bhaduri N,Sarkar K,Ghosh P,Sinha S,Ray A,Chatterjee A,Mukhopadhyay K

更新日期：2011-03-30 00:00:00

abstract：:The underlying mechanisms of autism and schizophrenia are poorly understood, partly due to a lack of dimension-specific research. Aberrant excitatory and inhibitory neurotransmission are implicated in both conditions, particularly in social dysfunction. This study investigates the extent to which the degree of autisti...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ford TC,Abu-Akel A,Crewther DP

更新日期：2019-01-10 00:00:00

abstract：BACKGROUND:Using a newly developed regional homogeneity (ReHo) approach, we were to explore the features of brain activity in patients with treatment-resistant depression (TRD) in resting state, and further to examine the relationship between abnormal brain activity in TRD patients and specific symptom factors derived ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Guo WB,Sun XL,Liu L,Xu Q,Wu RR,Liu ZN,Tan CL,Chen HF,Zhao JP

更新日期：2011-07-01 00:00:00

abstract：:1. Male hooded Lister rats were fed a liquid diet containing 10% absolute ethanol for 4-5 weeks. Control rats received the liquid diet in amounts controlled to produce equal weight gain. 2. The rats were tested 7.5 h after withdrawal of ethanol and 30 min after i.p. injection with nitrendipine, chlordiazepoxide or bac...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： File SE,Zharkovsky A,Hitchcott PK

更新日期：1992-01-01 00:00:00

abstract：:1. The effects of intravenous infusion of desipramine (1, 3, 10, and 60 mg/kg/day), amitriptyline, zimelidine, iprindole (3, 10, 30, 60, and 100 mg/kg/day each), imipramine (10, 30, and 100 mg/kg/day), or U-48753E (1, 3, 10, and 30 mg/kg/day) on the density of central beta-adrenergic receptors (beta-AR) were investiga...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Sethy VH,Day JS,Cooper MM

更新日期：1988-01-01 00:00:00

abstract：:Lithium remains the treatment of choice for many patients suffering from bipolar disorder. However, long-term treatment with lithium carries the potential to cause renal and thyroid dysfunction. Lithium-induced nephropathies are characterised by deterioration of urinary concentrating ability as well as, less frequentl...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Raedler TJ,Wittke S,Jahn H,Koessler A,Mischak H,Wiedemann K

更新日期：2008-04-01 00:00:00