Abstract：
OBJECTIVES:To identify and describe the factors that have led to new cases of HIV infection through mother-to-child transmission since the introduction of antiretroviral therapy in HIV-seropositive pregnant women (1997-2001) in Catalonia. METHODS:Systematic review of cases identified in the pediatric services of all the hospitals in Catalonia. RESULTS:Twenty-eight cases of pediatric HIV infection were identified: 9, 9, 8, 2 and 0 per year of birth from 1997 to 2001, respectively. Of 16 mothers with a diagnosis of known HIV infection before or during pregnancy, nine underwent antiretroviral prophylaxis during pregnancy (compliance was good in five, unknown in one and poor in one) and seven did not undergo prophylaxis (six refused it and no information was available in one). Of 12 mothers diagnosed after delivery, pregnancy was not monitored in five and was little or well-monitored in the remaining seven. Of mothers with well-monitored pregnancy, a serological HIV test was not performed in six and was negative in the first trimester in one. CONCLUSIONS:Mother-to-child transmission of HIV has decreased in the last few years in Catalonia, but infections have sometimes occurred through poor implementation of preventive measures. Pregnant women should be offered an HIV diagnostic test not only in the first trimester but also at the end of pregnancy if HIV exposure is suspected. In women with unmonitored pregnancies, rapid diagnostic tests for HIV should be used in the delivery room.
journal_name
Gac Sanitjournal_title
Gaceta sanitariaauthors
Ramos F,García-Fructuoso MT,Almeda J,Casabona J,Coll O,Fortuny C,Grupo ad hoc de infeccion pediátrica por VIH en Cataluña.doi
10.1016/s0213-9111(03)71747-6subject
Has Abstractpub_date
2003-07-01 00:00:00pages
275-82issue
4eissn
0213-9111issn
1578-1283pii
13051044journal_volume
17pub_type
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