Locally delivered antimicrobials for the treatment of chronic periodontitis.

abstract：OBJECTIVE:Oral squamous cell carcinoma (OSCC) represents 3%-4% of all cancers. Despite the increasing incidence of OSCC distant metastasis and poor prognosis, few animal models of OSCC distant metastasis have been reported. In this study, we established mouse models of OSCC lung metastasis by orthotopic and tail vein i...

journal_title：Oral diseases

authors： Marcazzan S,Dadbin A,Brachi G,Blanco E,Varoni EM,Lodi G,Ferrari M

更新日期：2020-08-07 00:00:00

abstract：BACKGROUND:Oral-facial-digital syndrome (OFDS) type 1 (OFD1) is an X-linked dominant condition associated with embryonic male lethality. It almost always affects the oral cavity, face, and digits. It is considered to be a ciliopathy caused by mutations in the OFD1 gene. A variety of mutations have been described, and a...

journal_title：Oral diseases

authors： Diz P,Alvarez-Iglesias V,Feijoo JF,Limeres J,Seoane J,Tomás I,Carracedo A

更新日期：2011-09-01 00:00:00

abstract：:HIV infection and AIDS are spreading rapidly among the world's children, especially among African-American and Hispanic children in the USA, and those in developing countries. Although recent research has identified several ways of preventing perinatal transmission of HIV, most of these methods are too expensive for w...

journal_title：Oral diseases

authors： Ramos-Gomez F

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:This review aims to evaluate the efficacy of xenogeneic collagen matrix (XCM) for the treatment of single or multiple gingival recessions in terms of clinical parameters and patient-related outcomes. MATERIALS AND METHODS:Various electronic databases (The Cochrane Central Register of Controlled Trials, MEDL...

journal_title：Oral diseases

authors： Huang JP,Liu JM,Wu YM,Chen LL,Ding PH

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the cysteine protease inhibitory properties of the human salivary cystatins S, SA and SN in order to identify potential in vivo target cysteine proteases which may include those involved in periodontal tissue destruction. In addition, the potential role of the salivar...

journal_title：Oral diseases

authors： Baron A,DeCarlo A,Featherstone J

更新日期：1999-07-01 00:00:00

abstract：:With a history of over 2000 years, traditional Chinese medicine (TCM) evolves into a unique system of diagnosing and treating illnesses. It is a challenge to convey the fundamentals of this traditional medicine to our Western colleagues because of the differences in language, philosophy and concept of diagnosis and tr...

journal_title：Oral diseases

authors： Zheng LW,Hua H,Cheung LK

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:We examined the content of YouTube(™) videos on mouth (oral) cancer and evaluated their usefulness in promoting early detection of oral cancer. MATERIALS AND METHODS:A systematic search of YouTube(™) for videos containing information on mouth cancer was conducted using the keywords 'mouth cancer' and 'oral ...

journal_title：Oral diseases

authors： Hassona Y,Taimeh D,Marahleh A,Scully C

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Orofacial granulomatosis (OFG) is a rare condition characterized by non-caseating granulomas in the orofacial region. Protease-Activated Receptors (PARs) play a role in inflammatory diseases in diverse human tissues. The aim of the study was to investigate the expression of PAR-1, PAR-2, MMP-2, MMP-9, COX-1, ...

journal_title：Oral diseases

authors： Ketabchi S,Massi D,Ficarra G,Rubino I,Franchi A,Paglierani M,Simoni A,Capodiferro S,Favia G,Maiorano E,Tarantini F,Cirino G,Santucci M

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:This systematic review was to evaluate the change of oral microbiome based on next-generation sequencing (NGS)-metagenomic analysis following periodontal interventions among systematically healthy subjects. MATERIALS AND METHODS:A structured search strategy consisting of "metagenomics" and "oral diseases" w...

journal_title：Oral diseases

authors： Zhang Y,Qi Y,Lo ECM,McGrath C,Mei ML,Dai R

更新日期：2020-05-11 00:00:00

abstract：OBJECTIVE:To investigate the clinicopathological characteristics and biologic behaviour of epithelioid hemangioendothelioma in the oral cavity. MATERIALS AND METHODS:The clinical features and pathological findings of nine cases with intraoral epithelioid hemangioendothelioma were reviewed, including immunohistochemist...

journal_title：Oral diseases

authors： Sun ZJ,Zhang L,Zhang WF,Chen XM,Lai FM,Zhao YF

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:This study was designed to establish a rat model of a critical size alveolar bone defect. MATERIALS AND METHODS:Standardized buccal or mesiobuccal alveolar bone defects were made around the right first mandibular molar of 12-week-old rats, and the left was used as a control. Alveolar bone healing was examine...

journal_title：Oral diseases

authors： Ebina H,Hatakeyama J,Onodera M,Honma T,Kamakura S,Shimauchi H,Sasano Y

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:The aim was to investigate the attitudes of people with HIV infection towards their own dental care provision and the possible implications for future resource allocation. DESIGN:Sixty-nine HIV positive subjects attending support groups in London were interviewed. Past and current dental visiting behaviour,...

journal_title：Oral diseases

authors： Gallagher PD,Gealer M,Birnbaum W

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:We examined the influence of in vitro aging on Campylobacter rectus (C. rectus) lipopolysaccharide (LPS)-stimulated prostaglandin (PG), E2 release frOm human gingival fibroblasts (HGFs). MATERIALS AND METHODS:LPS was prepared from C. rectus ATCC33238. HGFs were established from healing gingival tissue remove...

journal_title：Oral diseases

authors： Takiguchi H,Yamaguchi M,Mochizuki K,Abiko Y

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:To develop a novel test for chronic ulcerative stomatitis (CUS), a chronic immunologically mediated condition that produces oral ulcerations. Current diagnostic methods require expensive and technically demanding in situ immunofluorescence (IF) studies. DESIGN:An Enzyme-Linked ImmunoSorbent Assay (ELISA) was...

journal_title：Oral diseases

authors： Solomon LW,Stark PC,Winter L,Kumar V,Sinha S

更新日期：2010-03-01 00:00:00

abstract：:Studies of the malignant potential of oral lichen planus (OLP) have been hampered by inconsistencies in the diagnostic criteria used for OLP, the criteria adopted to identify a true case of malignant transformation in OLP, the risk factors for malignant transformation and the optimum management of patients to ensure t...

journal_title：Oral diseases

authors： Gonzalez-Moles MA,Scully C,Gil-Montoya JA

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Bisphosphonates are widely used to treat bone diseases such as osteoporosis. However, they may cause osteonecrosis of the jaw. Here, we investigated whether in vivo exposure to bisphosphonates has a different effect on long bone and jaw osteoclasts, and on the turnover of these different bones. MATERIALS AN...

journal_title：Oral diseases

authors： Vermeer J,Renders G,van Duin MA,Jansen I,Bakker LF,Kroon SA,de Vries TJ,Everts V

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence of EBV-DNA, CMV-DNA and HPV-DNA in oral healthy mucosa of HIV-infected and renal transplant patients. To associate the detection of viral genomes with laboratory parameters of immunodeficiency, gender, antiretroviral and immunosuppressive therapy. DESIGN:A cross-sectional analysi...

journal_title：Oral diseases

authors： Ammatuna P,Campisi G,Giovannelli L,Giambelluca D,Alaimo C,Mancuso S,Margiotta V

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:siRNA-induced gene silencing in the salivary gland using microbubble-enhanced sonoporation was used to develop an in vivo gene knockdown technique. METHODS:siRNA targeting rat glyceraldehyde-3-phosphate dehydrogenas (GAPDH) was mixed with echo-enhanced microbubbles and reverse-injected into rat parotid glan...

journal_title：Oral diseases

authors： Sakai T,Kawaguchi M,Kosuge Y

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to examine the prevalence of selected periodontal pathogens associated with HIV and non-HIV related periodontal lesions. METHODS:Subgingival plaque samples were obtained from both HIV-seropositive and HIV-seronegative patients affected with periodontal disease. DNA probes were used t...

journal_title：Oral diseases

authors： Tenenbaum H,Elkaim R,Cuisinier F,Dahan M,Zamanian P,Lang JM

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:Topically applied aluminum (AI) reduced fissure caries in rats with indigenous microflora, but neither therapeutic activity nor concentration effects have been studied in animals infected with caries-inducing bacteria. This study investigated the effects of solutions containing various AI concentrations on fo...

journal_title：Oral diseases

authors： Putt MS,Kleber CJ

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to compare the proliferation index of the epithelial cells between odontogenic keratocysts (OKC), orthokeratinized odontogenic cysts (OOC), dentigerous cysts (DC), and ameloblastomas. MATERIALS AND METHODS:The proliferation index, employing a novel cell proliferation marker ...

journal_title：Oral diseases

authors： Thosaporn W,Iamaroon A,Pongsiriwet S,Ng KH

更新日期：2004-01-01 00:00:00

abstract：:DNA methylation is an important regulator of gene transcription, and its role in carcinogenesis has been a topic of considerable interest in the last few years. Of the all epigenetic modifications, methylation, which represses transcription of the promoter region of tumor suppressor genes leading to gene silencing, ha...

journal_title：Oral diseases

authors： González-Ramírez I,García-Cuellar C,Sánchez-Pérez Y,Granados-García M

更新日期：2011-11-01 00:00:00

abstract：:Most viral infections encountered in resource-rich countries are relatively trivial and transient with perhaps fever, malaise, myalgia, rash (exanthema) and sometimes mucosal manifestations (enanthema), including oral in some. However, the apparent benignity may be illusory as some viral infections have unexpected con...

journal_title：Oral diseases

authors： Scully C,Samaranayake LP

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:The establishment of animal models of xenotransplantation can contribute to the elucidation of the molecular pathogenesis of ameloblastic fibrodentinomas (AFD) and it also provides an opportunity for drug tests. We aimed to evaluate the possibility of AFD tumour growth in a patient-derived xenograft (PDX) mo...

journal_title：Oral diseases

authors： Pereira NB,de Souza JC,Bastos VC,Fonseca FP,de Avelar GF,Castro WH,Dias AAM,Mosqueda-Taylor A,Gomez RS,Gomes CC

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:X-linked hypohidrotic ectodermal dysplasia (XLHED) is characterized by abnormalities of hair, teeth, and sweat glands, while non-syndromic hypodontia (NSH) affects only teeth. Mutations in Ectodysplasin A (EDA) underlie both XLHED and NSH. This study investigated the genetic causes of six hypohidrotic ectode...

journal_title：Oral diseases

authors： Zeng B,Lu H,Xiao X,Zhou L,Lu J,Zhu L,Yu D,Zhao W

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:Cyclosporine A (CsA) is used as an immunosuppressive agent and its prominent side effect is the induction of gingival overgrowth. Type I plasminogen activator inhibitor (PAI-1) has shown to play an important role in CsA-induced gingival overgrowth. However, little is known about whether factors can modulate ...

journal_title：Oral diseases

authors： Ho YC,Lin HJ,Tsai CH,Chang YC

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the levels, molecular forms and activation degree of matrix metalloproteinase-13 (MMP-13) in the gingival crevicular fluid (GCF) of patients with periodontal diseases and to correlate these findings with periodontal clinical parameters. METHODS:Sixty one subjects pa...

journal_title：Oral diseases

authors： Ilgenli T,Vardar-Sengul S,Gürkan A,Sorsa T,Stackelberg S,Köse T,Atilla G

更新日期：2006-11-01 00:00:00

abstract：:It has been slightly more than a decade since the classic mechanistic paradigm that defined the pathogenesis of mucositis was revised. A five-stage sequence of linked biological events forms the basis for our current understanding of how regimen-related mucosal injury occurs. The first stage is the initiation phase, a...

journal_title：Oral diseases

authors： Sonis ST

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the effectiveness of aloe vera containing herbal dentifrices in improving plaque control and gingival health. METHODS:A manual and electronic literature (MEDLINE and Cochrane Central Register of Controlled Trials) search was performed up to July 2012, for randomized controlled trials presenting ...

journal_title：Oral diseases

authors： Dhingra K

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:We assessed the aetiology of idiopathic condylar resorption by examining the effects of oestrogen and compressive mechanical stress under a low systemic oestrogen condition in temporomandibular joints (TMJ) caused by an ovariectomy. MATERIALS AND METHODS:Female rabbits were divided into non-ovariectomy (non-...

journal_title：Oral diseases

authors： Nogami S,Yamauchi K,Odashima K,Ito K,Iikubo M,Kumasaka A,Martinez-de la Cruz G,Gaggl A,Kumamoto H,Takahashi T

更新日期：2020-11-01 00:00:00