Down-regulation of endodermal Shh is required for gland formation in chicken stomach.

abstract：:Tetrapod fore-and hindlimbs have evolved from the pectoral and pelvic fins of an ancient vertebrate ancestor. In this ancestor, the pectoral fin appears to have arisen following the rostral homeotic recapitulation of an existing pelvic appendage (Tabin and Laufer (1993), Nature 361, 692-693). Thus the basic appendage ...

journal_title：Mechanisms of development

authors： Gibson-Brown JJ,Agulnik SI,Chapman DL,Alexiou M,Garvey N,Silver LM,Papaioannou VE

更新日期：1996-05-01 00:00:00

abstract：:Myogenin and CMD1, the chicken homologue of MyoD, transactivate the promoter of the alpha-subunit of the acetylcholine receptor (AChR) in chicken fibroblasts. The expression of these three genes was followed by in situ hybridization. In two-day-old embryos the CMD1 gene is expressed shortly before the AChR alpha-subun...

journal_title：Mechanisms of development

authors： Piette J,Huchet M,Duclert A,Fujisawa-Sehara A,Changeux JP

更新日期：1992-03-01 00:00:00

abstract：:Mll, Brg1 and Brm are vertebrate homologues of Drosophila trithorax group (trxG) genes. We isolated chicken Mll cDNA clones, and examined patterns of Mll, Brg1 and Brm expression in chick embryos. All three genes were expressed from embryonic stage 2 onwards. Mll transcripts were just detectable in all tissues by in s...

journal_title：Mechanisms of development

authors： Schofield J,Isaac A,Golovleva I,Crawley A,Goodwin G,Tickle C,Brickell P

更新日期：1999-01-01 00:00:00

abstract：:It is now well established that apoptosis is induced in response to mechanical strain. Indeed, increasing compressive forces induces apoptosis in confined spheroids of tumour cells, whereas releasing stress reduces apoptosis in spheroids cultivated in free suspension (Cheng et al., 2009). Apoptosis can also be induced...

journal_title：Mechanisms of development

authors： Ambrosini A,Gracia M,Proag A,Rayer M,Monier B,Suzanne M

更新日期：2017-04-01 00:00:00

abstract：:The formation of mesoderm is an important developmental process of vertebrate embryos, which can be broken down into several steps; mesoderm induction, patterning, morphogenesis and differentiation. Although mesoderm formation in Xenopus has been intensively studied, much remains to be learned about the molecular even...

journal_title：Mechanisms of development

authors： Chen JA,Voigt J,Gilchrist M,Papalopulu N,Amaya E

更新日期：2005-03-01 00:00:00

abstract：:The vertebrate neural tube develops by two distinct mechanisms. Anteriorly, in the brain and future trunk (cervicothoracic) region, 'primary neurulation' occurs, where an epithelial sheet rolls or bends into a tube. Posteriorly, in the future lumbar and tail region, the neural tube forms by 'secondary neurulation', wh...

journal_title：Mechanisms of development

authors： Lowery LA,Sive H

更新日期：2004-10-01 00:00:00

abstract：:Tribolium castaneum is a well-characterised model insect, whose short germ-band mode of embryonic development is characteristic of many insect species and differs from the exhaustively studied Drosophila. Mechanisms of early neurogenesis, however, show significant conservation with Drosophila, as a characteristic patt...

journal_title：Mechanisms of development

authors： Kux K,Kiparaki M,Delidakis C

更新日期：2013-04-01 00:00:00

abstract：:During Drosophila embryogenesis, the attachment of somatic muscles to epidermal tendon cells requires heterodimeric PS-integrin proteins (alpha- and beta-subunits). The alpha-subunits are expressed complementarily, either tendon cell- or muscle-specific, whereas the beta-integrin subunit is expressed in both tissues. ...

journal_title：Mechanisms of development

authors： Chanana B,Graf R,Koledachkina T,Pflanz R,Vorbrüggen G

更新日期：2007-07-01 00:00:00

abstract：:We have identified a Drosophila gene encoding a putative receptor tyrosine kinase by screening a genomic DNA library with a DNA probe for a Drosophila homolog of fibroblast growth factor receptors. The newly isolated gene codes for a transmembrane protein most similar in sequence to a mammalian proto-oncogene ret; thu...

journal_title：Mechanisms of development

authors： Sugaya R,Ishimaru S,Hosoya T,Saigo K,Emori Y

更新日期：1994-02-01 00:00:00

abstract：:Although the molecular mechanisms directing anteroposterior patterning of the Drosophila embryo (long-germband mode) are well understood, how these mechanisms were evolved from an ancestral mode of insect embryogenesis remains largely unknown. In order to gain insight into mechanisms of evolution in insect embryogenes...

journal_title：Mechanisms of development

authors： Shinmyo Y,Mito T,Matsushita T,Sarashina I,Miyawaki K,Ohuchi H,Noji S

更新日期：2005-02-01 00:00:00

abstract：:The leucine zipper transcription factor TSC-22 (TGF-beta1 Stimulated Clone-22) was first isolated from a mouse osteoblast cell line as an immediate-early target gene of TGF-beta1. However, work with other cell lines, as well as with a Drosophila homolog, bunched, suggests that it is an effector gene of various growth ...

journal_title：Mechanisms of development

authors： Dohrmann CE,Belaoussoff M,Raftery LA

更新日期：1999-06-01 00:00:00

abstract：:Members of the cysteine-rich protein (CRP) define a subclass of LIM-only proteins implicated mainly in muscle differentiation. Until now, very little is known concerning the expression of CRP encoding genes during vertebrate development. We describe here the isolation of a trout (Oncorhynchus mykiss) gene encoding a c...

journal_title：Mechanisms of development

authors： Delalande JM,Rescan PY

更新日期：1998-08-01 00:00:00

abstract：:The diencephalon is the caudal part of the developing forebrain that gives rise to the epithalamus, thalamus, hypothalamus and retina. The mature diencephalon is functionally and anatomically parceled into well-defined nuclei. In an effort to understand how this region of the brain develops we examined the expression ...

journal_title：Mechanisms of development

authors： Lim Y,Golden JA

更新日期：2002-07-01 00:00:00

abstract：:Each sensory organ of the Drosophila peripheral nervous system is derived from a single sensory organ precursor cell (SOP). These originate in territories defined by expression of the proneural genes of the Achaete-Scute complex (AS-C). Formation of ectopic sensilla outside these regions is prevented by transcriptiona...

journal_title：Mechanisms of development

authors： Badenhorst P,Finch JT,Travers AA

更新日期：2002-09-01 00:00:00

abstract：:Blood vessel maturation, which is characterized by the investment of vascular smooth muscle cells (vSMCs) around developing blood vessels, begins when vessels remodel into a hierarchy of proximal arteries and proximal veins that branch into smaller distal capillaries. The ultimate result of maturation is formation of ...

journal_title：Mechanisms of development

authors： Padget RL,Mohite SS,Hoog TG,Justis BS,Green BE,Udan RS

更新日期：2019-04-01 00:00:00

abstract：:ADAM19 is a member of the meltrin subfamily of ADAM metalloproteases. In Xenopus, ADAM19 is present as a maternal transcript. Zygotic expression starts during gastrulation and is apparent in the dorsal blastopore lip. ADAM19 expression through neurulation and tailbud formation becomes enriched in dorsal structures suc...

journal_title：Mechanisms of development

authors： Neuner R,Cousin H,McCusker C,Coyne M,Alfandari D

更新日期：2009-03-01 00:00:00

abstract：:Drosophila melanogaster possesses a single gene, Dm myb, that is closely related to the vertebrate family of Myb genes, which encode transcription factors involved in regulatory decisions affecting cell proliferation, differentiation and apoptosis. In proliferating cells, the Dm myb gene product, DMyb, promotes both S...

journal_title：Mechanisms of development

authors： Fung SM,Ramsay G,Katzen AL

更新日期：2003-06-01 00:00:00

abstract：:Proper metazoan mesoderm development requires the function of a basic helix-loop-helix (bHLH) transcription factor, Twist. Twist-containing dimers regulate the expression of target genes by binding to E box promoter elements containing the site CANNTG. In Caenorhabditis elegans, CeTwist functions in a subset of mesode...

journal_title：Mechanisms of development

authors： Zhao J,Wang P,Corsi AK

更新日期：2007-05-01 00:00:00

abstract：:To examine the role of the Oct-6 gene in Schwann cell differentiation we have cloned and characterized the chicken and zebrafish homologues of the mouse Oct-6 gene. While highly homologous in the Pit1-Oct1/2-Unc86 (POU) domain, sequence similarities are limited outside this domain. Both genes are intronless and both p...

journal_title：Mechanisms of development

authors： Levavasseur F,Mandemakers W,Visser P,Broos L,Grosveld F,Zivkovic D,Meijer D

更新日期：1998-06-01 00:00:00

abstract：:The Drosophila wing is a classical model for studying the generation of developmental patterns. Previous studies have suggested that vein primordia form at boundaries between discrete sectors of gene expression along the antero-posterior (A/P) axis in the larval wing imaginal disc. Observation that the vein marker rho...

journal_title：Mechanisms of development

authors： Crozatier M,Glise B,Khemici V,Vincent A

更新日期：2003-05-01 00:00:00

abstract：:Active repression of gene expression mediated by unliganded nuclear receptors plays crucial roles in early development of vertebrates. N-CoR (nuclear receptor co-repressor) is the first identified co-repressor that can repress retinoic acid (RA) inducible gene transcription in the absence of RA. Previously, N-CoR was ...

journal_title：Mechanisms of development

authors： Xu F,Li K,Tian M,Hu P,Song W,Chen J,Gao X,Zhao Q

更新日期：2009-10-01 00:00:00

abstract：:During early vertebrate development, a series of neuromeres divides the central nervous system from the forebrain to the spinal cord. Here we examine in more detail the expression of Wnt-3, a member of the Wnt gene family of secreted proteins, in the developing diencephalon, in comparison to the expression of the home...

journal_title：Mechanisms of development

authors： Salinas PC,Nusse R

更新日期：1992-12-01 00:00:00

abstract：:We have characterised a short (30 base pair) element from the Xenopus Wnt-5a promoter which is nearly identical to one located in the human Wnt-5a promoter, and has the same position relative to the transcription start site. When placed in front of a LacZ gene, this element can reproduce the same expression pattern ob...

journal_title：Mechanisms of development

authors： Morgan R,Hooiveld MH,In der Reiden P,Durston AJ

更新日期：1999-07-01 00:00:00

abstract：:Cell-to-cell communication is absolutely essential for multicellular organisms. Both animals and plants use chemicals called hormones for intercellular signaling. However, multicellularity of plants and animals has evolved independently, which led to establishment of distinct strategies in order to cope with variation...

journal_title：Mechanisms of development

authors： Löfke C,Luschnig C,Kleine-Vehn J

更新日期：2013-01-01 00:00:00

abstract：:pebble (pbl) is required for cytokinesis during postblastoderm mitoses (Hime, G., Saint, R., 1992. Zygotic expression of the pebble locus is required for cytokinesis during the postblastoderm mitoses of Drosophila. Development 114, 165-171; Lehner, C.F., 1992. The pebble gene is required for cytokinesis in Drosophila....

journal_title：Mechanisms of development

authors： Prokopenko SN,Saint R,Bellen HJ

更新日期：2000-02-01 00:00:00

abstract：:When an amphibian limb, cockroach leg or Drosophila imaginal disc is subjected to a surgical operation, it is capable of regenerating or duplicating certain parts. Although the structure of the regenerated tissue varies depending on the location and mass of the amputated or transplanted part, it can be predicted from ...

journal_title：Mechanisms of development

authors： Kondo S

更新日期：1992-12-01 00:00:00

abstract：:We have analysed the cell lineage relationships between larval and imaginal mesodermal primordia at the blastoderm stage by homotopic single cell transplantations. The primordia of adepithelial cells, the precursors of adult thoracic muscles, are restricted to the region from 50 to 65% egg length within the ventrally ...

journal_title：Mechanisms of development

authors： Holz A,Meise M,Janning W

更新日期：1997-02-01 00:00:00

abstract：:Cloning and sequencing of mouse Mf2 (mesoderm/mesenchyme forkhead 2) cDNAs revealed an open reading frame encoding a putative protein of 492 amino acids which, after in vitro translation, binds to a DNA consensus sequence. Mf2 is expressed at high levels in the ventral region of newly formed somites, in sclerotomal de...

journal_title：Mechanisms of development

authors： Wu SC,Grindley J,Winnier GE,Hargett L,Hogan BL

更新日期：1998-01-01 00:00:00

abstract：:The spatial and temporal analysis of GATA-3 expression pattern in the human embryo revealed its expression in new anatomical sites. These include the endoderm of the primitive foregut, pharynx and allantois, the branchial arches and the mesenchymal cells surrounding the stomach and dorsal aorta. On the other hand, hum...

journal_title：Mechanisms of development

authors： Debacker C,Catala M,Labastie MC

更新日期：1999-07-01 00:00:00

abstract：:The Drosophila genes eyeless, eyes absent, sine oculis and dachshund cooperate as components of a network to control retinal determination. Vertebrate homologues of these genes have been identified and implicated in the control of cell fate. We present the cloning and characterization of mouse Dach2, a homologue of da...

journal_title：Mechanisms of development

authors： Davis RJ,Shen W,Sandler YI,Heanue TA,Mardon G

更新日期：2001-04-01 00:00:00