Abstract：
:Tay-Sachs disease is a fatal genetic disease affecting Jewish infants of eastern European ancestry. While the disease may go unrecognized until nearly one year of age, death occurs by age three or four. Community screening programs have been organized to detect carriers of this autosomal recessive trait. Prenatal diagnosis now allows carrier couples to have normal children without the risk of having an affected child. These programs hopefully will serve as models for the future prevention of other genetic diseases.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Jackson LG,Nimoityn P,Faust HS,Glazerman LRsubject
Has Abstractpub_date
1976-04-01 00:00:00pages
111-4issue
4eissn
0002-838Xissn
1532-0650journal_volume
13pub_type
杂志文章abstract：:Prompt diagnosis of problems in the first trimester of pregnancy is facilitated by ultrasound scanning and quantitative serum human chorionic gonadotropin and progesterone testing. When used appropriately, these tests can determine whether a patient has a normal early pregnancy, a miscarriage, a missed abortion, an ec...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-11-01 00:00:00
abstract：:Skin laceration repair is an important skill in family medicine. Sutures, tissue adhesives, staples, and skin-closure tapes are options in the outpatient setting. Physicians should be familiar with various suturing techniques, including simple, running, and half-buried mattress (corner) sutures. Although suturing is t...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2008-10-15 00:00:00
abstract：:Eating disorders are life-threatening conditions that are challenging to address; however, the primary care setting provides an important opportunity for critical medical and psychosocial intervention. The recently published Diagnostic and Statistical Manual of Mental Disorders, 5th ed., includes updated diagnostic cr...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：:Atrial fibrillation is a supraventricular arrhythmia that adversely affects cardiac function and increases the risk of stroke. It is the most common arrhythmia and a major source of morbidity and mortality; its prevalence increases with age. Pulse rate is sensitive, but not specific, for diagnosis, and suspected atria...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2016-09-15 00:00:00
abstract：:Myocardial perfusion imaging with stress testing by exercise or pharmacologic methods and functional evaluation of the left ventricle are useful in many patients. Uses include determination of diagnosis and prognosis of patients with coronary artery disease, preoperative evaluation, management and risk stratification ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：:The principal means of evaluating perimenopausal bleeding is endometrial biopsy performed in the office. With the rising incidence of endometrial cancer, an accurate diagnosis is imperative. Outpatient endometrial biopsy is well accepted by patients, provides ample tissue for histologic examination and has good diagno...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
abstract：:Aspirin should not be used to treat acute febrile viral illness in children. (Strength of Recommendation [SOR]: C, based on case-control studies). Although no causal link has been proven, data from case-control and historic cohort studies demonstrate an association between aspirin use and Reye syndrome. The risk of Re...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2009-12-15 00:00:00
abstract：:Health literacy includes a set of skills needed to make appropriate health decisions and successfully navigate the health care system. These skills include reading, writing, numeracy, communication, and, increasingly, the use of electronic technology. National data indicate that more than one-third of U.S. adults have...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2015-07-15 00:00:00
abstract：:Atrial fibrillation is the most common arrhythmia in patients visiting a primary care practice. Although many patients with atrial fibrillation experience relief of symptoms with control of the heart rate, some patients require restoration of sinus rhythm. External direct current (DC) cardioversion is the most effecti...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1998-08-01 00:00:00
abstract：:The peak expiratory flow rate (PEFR) may be measured in the office or at home with an inexpensive, hand-held meter. Measurement of the PEFR provides a rapid, objective means of diagnosing and monitoring asthma. Use of the peak flow meter permits early detection of deteriorating function, allowing timely institution of...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:Cirrhosis is a diffuse process characterized by fibrosis and the conversion of normal liver architecture into structurally abnormal nodules. The modified Child-Pugh score, which ranks the severity of cirrhosis based on signs and liver function test results, has been shown to predict survival. Strategies have been esta...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2001-11-15 00:00:00
abstract：:Federally funded health centers and the National Health Service Corps (NHSC) depend on family physicians (FPs) and general practitioners (GPs) to meet the needs of millions of medically underserved people. Policy makers and workforce planners should consider how changes in the production of FPs would affect these prog...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2005-07-15 00:00:00
abstract：:Pretibial myxedema is a localized dermopathy seen in patients with past or present hyperthyroidism. Massive intradermal deposition of mucin (acid mucopolysaccharide) produces the classic indurated nodules or plaques on the anterior lower legs. Most patients have elevated levels of LATS in their serum; however, this ap...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:Pharmacologic agents that attenuate the influence of the renin-angiotensin-aldosterone system are known to reduce systemic arterial blood pressure through vasodilatory action and enhanced renal clearance of sodium and water. Angiotensin-converting enzyme inhibitors are known to antagonize the renin-angiotensin-aldoste...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1996-02-01 00:00:00
abstract：:Menière's disease may be the underlying cause of dizziness, which is a common presenting complaint. This disease is differentiated from other causes of dizziness by its classic constellation of four symptoms; dizziness characterized as episodic spinning or whirling vertigo; fluctuating, low-frequency sensorineural hea...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1997-03-01 00:00:00
abstract：:Because the prevalence of urinary incontinence increases with age, a working knowledge of the diagnosis and treatment of the various types of urinary incontinence is fundamental to the care of women. As the population of the United States ages, primary care physicians can expect to see an increasing number of patients...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-01 00:00:00
abstract：:Spinal cord compression from metastatic cancer is a medical emergency. Prompt intervention affords the best chance for successful recovery, while delay may result in devastating neurologic impairment. In the appropriate clinical setting, emergency myelography should be done to confirm the diagnosis of metastatic disea...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:The U.S. Preventive Services Task Force recommends that clinicians screen adults for alcohol misuse and provide persons engaged in risky or hazardous drinking behaviors with brief behavioral counseling to reduce alcohol misuse. However, only a minority of American adults with high-risk alcohol use receive treatment. T...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2016-03-15 00:00:00
abstract：:Adopted children are emotionally vulnerable. Adoptive parents must cope with more complex problems than biologic parents. The family physician can provide valuable counseling. Preadoption counseling focuses on motivation and ambivalence. After adoption, however, serious, sometimes predictable, issues arise, such as: h...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:The U.S. Preventive Services Task Force (USPSTF) has issued recommendations on behavioral counseling to prevent sexually transmitted infections (STIs) and recommendations about screening for individual STIs. Clinicians should obtain a sexual history to assess for behaviors that increase a patient's risk. Community and...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2016-12-01 00:00:00
abstract：:The acute and chronic effects of alcohol on bone, muscle and peripheral nerves are not well appreciated. Bone complications include traumatic fractures, osteoporosis and osteonecrosis. In muscle, a sustained bout of heavy drinking may cause rhabdomyolysis, while chronic alcohol abuse may produce proximal myopathy. In ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
abstract：:Senile dementia of the Binswanger's type is a term used to describe a dementia syndrome characterized by onset in the sixth or seventh decade of life, subcortical neurologic deficits, psychiatric disorders and evidence of hypertension or systemic vascular disease. The status of senile dementia of the Binswanger's type...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1998-12-01 00:00:00
abstract：:"White coat" or "office" hypertension is often defined as the transient rise or elevation of blood pressure that occurs in the medical setting. Patients with these elevated readings have normal ambulatory pressures as determined by individual home blood pressure measurements or continuous 24-hour blood pressure monito...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：:The differential diagnosis of eyelid erythema and edema is broad, ranging from benign, self-limiting dermatoses to malignant tumors and vision-threatening infections. A definitive diagnosis usually can be made on physical examination of the eyelid and a careful evaluation of symptoms and exposures. The finding of a sw...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2007-12-15 00:00:00
abstract：:Chlamydial cervicitis has the potential for serious gynecologic complications, including pelvic inflammatory disease, infertility and ectopic pregnancy. In the pregnant patient, this infection is associated with premature rupture of membranes and increased fetal morbidity and mortality. In addition, infants infected b...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-06-01 00:00:00
abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including significant upper gastrointestinal tract bleeding. Older persons, persons taking anticoagulants, and persons with a history of upper gastrointestinal tract bleeding associated with NSAIDs are at especia...
journal_title：American family physician
pub_type： 杂志文章,实务指引
doi：
更新日期：2009-12-15 00:00:00
abstract：:Tic disorders and Tourette's syndrome are conditions that primary care physicians are likely to encounter. Up to 20 percent of children have at least a transient tic disorder at some point. Once believed to be rare, Tourette's syndrome is now known to be a more common disorder that represents the most complex and seve...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-04-15 00:00:00
abstract：:Common anorectal conditions include hemorrhoids, perianal pruritus, anal fissures, functional rectal pain, perianal abscess, condyloma, rectal prolapse, and fecal incontinence. Although these are benign conditions, symptoms can be similar to those of cancer, so malignancy should be considered in the differential diagn...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2020-01-01 00:00:00
abstract：:Hypertension is the most common chronic condition treated by family physicians. Elevated blood pressure is associated with an increased risk of heart failure, myocardial infarction, cerebrovascular disease, and death. Treatment of hypertension reduces the risk of these events. Several lifestyle modifications are assoc...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2015-02-01 00:00:00
abstract：:A systematic approach to the interpretation of ambulatory electrocardiographic recordings facilitates analysis and improves accuracy. The method suggested includes a mnemonic and a standardized interpretation form. The mnemonic facilitates recall of key technical and patient-specific parameters involved in the prepara...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
