Drugs for conversion of atrial fibrillation.

Abstract:

:Atrial fibrillation is the most common arrhythmia in patients visiting a primary care practice. Although many patients with atrial fibrillation experience relief of symptoms with control of the heart rate, some patients require restoration of sinus rhythm. External direct current (DC) cardioversion is the most effective means of converting atrial fibrillation to sinus rhythm. Pharmacologic cardioversion, although less effective, offers an alternative to DC cardioversion. Several advances have been made in antiarrhythmic medications, including the development of ibutilide, a class III antiarrhythmic drug indicated for acute cardioversion of atrial fibrillation. Other methods of pharmacologic and nonpharmacologic cardioversion remain under development. Until the results of several large-scale randomized clinical trials are available, the decision to choose cardioversion or maintenance of sinus rhythm must be individualized, based on relief of symptoms and reduction of the morbidity and mortality associated with atrial fibrillation.

journal_name

Am Fam Physician

authors

Dell'Orfano JT,Luck JC,Wolbrette DL,Patel H,Naccarelli GV

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

471-80

issue

2

eissn

0002-838X

issn

1532-0650

journal_volume

58

pub_type

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