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The impact of gastrointestinal symptoms on health status in patients with cardiovascular disease.

Abstract：

BACKGROUND:Drugs for the management of cardiovascular disease may provoke gastrointestinal discomfort and complications. AIM:To evaluate whether upper gastrointestinal symptoms affect the health status of patients with cardiovascular disease. METHODS:Two weeks after discharge, 958 consecutive patients, who had been admitted to the Coronary Care Unit of the University Hospital Nijmegen between January and September 2001, were sent a questionnaire for the evaluation of gastrointestinal symptoms and health status. RESULTS:The questionnaire was returned by 632 patients (66%), with 334 patients (53%) reporting gastrointestinal symptoms. The self-rated health status (mean and 95% confidence interval), evaluated by visual analogue scale, was 70 (68-72) for patients without and 61 (59-63) for patients with gastrointestinal symptoms (P = 0.001). Patients with gastrointestinal symptoms reported significantly higher rates of problems with mobility (50% vs. 37%), self-care (19% vs. 10%), usual activities (70% vs. 52%), pain/discomfort (96% vs. 38%) and anxiety/depression (41% vs. 20%) when compared with those without gastrointestinal symptoms. CONCLUSION:Upper gastrointestinal symptoms strongly impaired the health status of patients with cardiovascular disease.

journal_name

Aliment Pharmacol Ther

journal_title

Alimentary pharmacology & therapeutics

authors

Laheij RJ,Van Rossum LG,Krabbe PF,Jansen JB,Verheugt FW

doi

10.1046/j.1365-2036.2003.01542.x

subject

Has Abstract

pub_date

2003-04-01 00:00:00

pages

881-5

issue

7

eissn

0269-2813

issn

1365-2036

pii

1542

journal_volume

17

pub_type

杂志文章

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