TAP1 and TAP2 polymorphisms analysis in northwestern Colombian patients with systemic lupus erythematosus.

abstract：BACKGROUND:Physical disability is part of the end point measures in rheumatoid arthritis clinical trials. The Stanford Health Assessment Questionnaire Disability Index (HAQ DI) is often used for this purpose but lacks international uniformity owing to variations in the translated and adapted questionnaires and variatio...

journal_title：Annals of the rheumatic diseases

authors： Zandbelt MM,Welsing PM,van Gestel AM,van Riel PL

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:To develop a preliminary composite psoriatic disease activity index (CPDAI) for psoriasis and psoriatic arthritis. METHODS:Five domains were assessed and specific instruments were employed for each domain to determine the extent of domain involvement and the effect of that involvement on quality of life/fun...

journal_title：Annals of the rheumatic diseases

authors： Mumtaz A,Gallagher P,Kirby B,Waxman R,Coates LC,Veale J D,Helliwell P,FitzGerald O

更新日期：2011-02-01 00:00:00

abstract：:A simple method is described which allows sequential monitoring of the endocytic activity of blood and synovial fluid cells from rheumatoid arthritis patients undergoing therapy with levamisole. Evidence of immediate (24 hours) and long-term (5-7 weeks) cellular phagocytic enhancement is presented. ...

journal_title：Annals of the rheumatic diseases

authors： Wynne KM,Dieppe PA,Scott J,Huskisson EC

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:To evaluate new classification criteria for peripheral spondyloarthritis (SpA) in patients with SpA with peripheral manifestations only. METHODS:In this Assessment of SpondyloArthritis international Society (ASAS) study, two prespecified sets of criteria were compared against the European Spondylarthropathy ...

journal_title：Annals of the rheumatic diseases

authors： Rudwaleit M,van der Heijde D,Landewé R,Akkoc N,Brandt J,Chou CT,Dougados M,Huang F,Gu J,Kirazli Y,Van den Bosch F,Olivieri I,Roussou E,Scarpato S,Sørensen IJ,Valle-Oñate R,Weber U,Wei J,Sieper J

更新日期：2011-01-01 00:00:00

abstract：:The circulating levels of hyaluronate were determined in 36 patients with scleroderma and in 36 control subjects matched for age and sex. The mean serum hyaluronate concentration in patients with progressive systemic sclerosis (n = 25) was 131 +/- 67 (SD) microgram/l and significantly greater (p less than 0.001) than ...

journal_title：Annals of the rheumatic diseases

authors： Engström-Laurent A,Feltelius N,Hällgren R,Wasteson A

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:In the present work, the frequency of inherited polymorphisms of the beta2 adrenergic receptor (beta2AR) gene and their association with rheumatoid arthritis (RA) as well as human leukocyte antigen (HLA)-DRB1 alleles was examined. METHODS:An allele-specific polymerase chain reaction was used to determine the...

journal_title：Annals of the rheumatic diseases

authors： Malysheva O,Pierer M,Wagner U,Wahle M,Wagner U,Baerwald CG

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Collagen-induced arthritis (CIA) is the most commonly used model of rheumatoid arthritis (RA). In both CIA and RA there is an increase in the cellular content of the synovium, this being dominated by macrophages. OBJECTIVE:To assess the impact of etoposide, a topoisomerase II antagonist known to induce mono...

journal_title：Annals of the rheumatic diseases

authors： Verdrengh M,Jonsson IM,Zaether O,Bajtner E,Holmdahl R,Tarkowski A

更新日期：2002-09-01 00:00:00

abstract：:Neutrophil chemiluminescence was determined in patients with active rheumatoid arthritis. Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids. A correlation with clinical and ...

journal_title：Annals of the rheumatic diseases

authors： Magaro M,Altomonte L,Zoli A,Mirone L,De Sole P,Di Mario G,Lippa S,Oradei A

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:To determine whether 17beta-oestradiol (E2) modulates interleukin (IL) 1beta-induced proteoglycan degradation in chondrocytes, and to analyse the part played by metalloproteinases (MMPs) in this process. METHODS:Primary cultured rabbit articular chondrocytes were prepared and treated with 10 ng/ml IL1beta co...

journal_title：Annals of the rheumatic diseases

authors： Richette P,Dumontier MF,François M,Tsagris L,Korwin-Zmijowska C,Rannou F,Corvol MT

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Whether preradiographic lesions in knees at risk for osteoarthritis are incidental versus disease is unclear. We hypothesised, in persons without but at higher risk for knee osteoarthritis, that: 12-48 month MRI lesion status worsening is associated with 12-48 month incident radiographic osteoarthritis (obje...

journal_title：Annals of the rheumatic diseases

authors： Sharma L,Nevitt M,Hochberg M,Guermazi A,Roemer FW,Crema M,Eaton C,Jackson R,Kwoh K,Cauley J,Almagor O,Chmiel JS

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To study the correlation between ankle and knee cartilage morphology to test the hypothesis that knee joint cartilage loss in gonarthritis can be estimated retrospectively using quantitative MRI analysis of the knee and ankle and established regression equations; and to test the hypothesis that sex difference...

journal_title：Annals of the rheumatic diseases

authors： Eckstein F,Siedek V,Glaser C,Al-Ali D,Englmeier KH,Reiser M,Graichen H

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To compare three questions on knee pain with respect to determined prevalence and associations with disability and structural change. METHODS:Postal survey to 4057 men and women aged 40-79 years. Knee pain was defined by three questions: (A) "Have you ever had pain in or around the knee on most days for at l...

journal_title：Annals of the rheumatic diseases

authors： O'Reilly SC,Muir KR,Doherty M

更新日期：1996-12-01 00:00:00

abstract：:Ten patients (8 female, 2 male) with systemic lupus erythematosus (SLE) were entered into an open trial with the anabolic steroid 19-nortestosterone (19-nor). Their clinical condition did not improve, nor were significant changes observed in the majority of laboratory data. However, overall the platelet count rose, an...

journal_title：Annals of the rheumatic diseases

authors： Hazelton RA,McCruden AB,Sturrock RD,Stimson WH

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Mast cells have been implicated in the pathogenesis of arthritis, but elucidation of their precise role has been hampered by a lack of efficient and selective inhibitors of their function. OBJECTIVE:To elucidate the role of mast cells in the pathogenesis of rheumatoid arthritis (RA) and to assess whether ap...

journal_title：Annals of the rheumatic diseases

authors： Juurikivi A,Sandler C,Lindstedt KA,Kovanen PT,Juutilainen T,Leskinen MJ,Mäki T,Eklund KK

更新日期：2005-08-01 00:00:00

abstract：:Monoclonal antibodies have proved to be extremely valuable additions to conventional treatment for rheumatic diseases. However, despite the general trend towards "humanisation", these drugs remain immunogenic in clinical settings, baffling drug developers. In principle, humanised and fully human monoclonal antibodies ...

journal_title：Annals of the rheumatic diseases

authors： Scott DW,De Groot AS

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To investigate the association between baseline serum adipokines levels-leptin, adiponectin and resistin-and long-term progression of hand osteoarthritis (HOA). METHODS:Baseline and 6-year radiographs of 164 patients (mean age 60 years, 81% women) with HOA (defined as a Kellgren and Lawrence score ≥2 in at l...

journal_title：Annals of the rheumatic diseases

authors： Yusuf E,Ioan-Facsinay A,Bijsterbosch J,Klein-Wieringa I,Kwekkeboom J,Slagboom PE,Huizinga TW,Kloppenburg M

更新日期：2011-07-01 00:00:00

abstract：:Alefacept is a bioengineered fusion protein of soluble lymphocyte function antigen (LFA-3) with Fc fragments of IgG1. It is marketed in many countries for the treatment of moderate to severe psoriasis. This paper reviews the data supporting the use of alefacept in psoriasis and psoriatic arthritis. ...

journal_title：Annals of the rheumatic diseases

authors： Gottlieb AB

更新日期：2005-11-01 00:00:00

abstract：:The immune response against two herpesviruses has been determined in sera and matched synovial fluids of patients with rheumatoid arthritis (RA) and compared with that of a healthy control population. The increased level of antibody to Epstein-Barr virus (EBV) induced antigens in patients with RA resembles the antibod...

journal_title：Annals of the rheumatic diseases

authors： Musiani M,Zerbini M,Ferri S,Plazzi M,Gentilomi G,La Placa M

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the presence of flow by Doppler ultrasound (DUS) in the wrist and finger joints (carpometacarpal 1 (CMC1), metacarpophalangeal (MCP), and proximal interphalangeal (PIP) joints) of healthy controls. METHODS:Twenty seven healthy volunteers (15 women, 12 men; mean age 45 years, range 18-93) with a t...

journal_title：Annals of the rheumatic diseases

authors： Terslev L,Torp-Pedersen S,Qvistgaard E,von der Recke P,Bliddal H

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate serum interleukin (IL) 12 concentration in patients with juvenile chronic arthritis (JCA), according to disease subtype, activity, and duration. IL12 has been demonstrated to prime the selective expansion of T helper (Th) cells with a Th1-type pattern of cytokine product...

journal_title：Annals of the rheumatic diseases

authors： Gattorno M,Picco P,Vignola S,Stalla F,Buoncompagni A,Pistoia V

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To elucidate the differential role of peptidyl arginine deiminase 4 (PADI4) polymorphism in rheumatoid arthritis (RA) between Asian and European populations, possible gene-environmental interactions among the PADI4 polymorphism, sex and smoking status were analysed. METHODS:Three independent sets of case-con...

journal_title：Annals of the rheumatic diseases

authors： Kochi Y,Thabet MM,Suzuki A,Okada Y,Daha NA,Toes RE,Huizinga TW,Myouzen K,Kubo M,Yamada R,Nakamura Y,Yamamoto K

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Despite the importance of timely management of patients with inflammatory arthritis (IA), delays exist in its diagnosis and treatment. OBJECTIVE:To perform a systematic literature review to identify strategies addressing these delays to inform an American College of Rheumatology (ACR)/European League Agains...

journal_title：Annals of the rheumatic diseases

authors： Villeneuve E,Nam JL,Bell MJ,Deighton CM,Felson DT,Hazes JM,McInnes IB,Silman AJ,Solomon DH,Thompson AE,White PH,Bykerk VP,Emery P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To determine concentrations of chondroitin sulphate (CS) and keratan sulphate (KS) epitopes, glycosaminoglycans (GAGs) and hyaluronan (HA) in knee synovial fluid (SF) from normal subjects and patients with osteoarthritis (OA) or rheumatoid arthritis (RA), to test whether these variables may be used as marker...

journal_title：Annals of the rheumatic diseases

authors： Belcher C,Yaqub R,Fawthrop F,Bayliss M,Doherty M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease with limited reliable diagnostic biomarkers. We investigated whether gene methylation could meet sensitivity and specificity criteria for a robust biomarker. METHODS:IFI44L promoter methylation was examined using DNA samples from a disc...

journal_title：Annals of the rheumatic diseases

authors： Zhao M,Zhou Y,Zhu B,Wan M,Jiang T,Tan Q,Liu Y,Jiang J,Luo S,Tan Y,Wu H,Renauer P,Del Mar Ayala Gutiérrez M,Castillo Palma MJ,Ortega Castro R,Fernández-Roldán C,Raya E,Faria R,Carvalho C,Alarcón-Riquelme ME,Xiang Z

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Increasing age at onset has been associated with worse outcome in rheumatoid arthritis, although there are few data from unselected inception cohorts. HYPOTHESIS:Increasing age is associated with a higher risk of erosions at presentation, and this increase is not explained by age-related disease confounders...

journal_title：Annals of the rheumatic diseases

authors： Bukhari M,Lunt M,Barton A,Bunn D,Silman A,Symmons D

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Knee osteoarthritis (OA) is a major cause of pain and functional limitation in older adults, yet longer-term studies of medical treatment of OA are limited. OBJECTIVE:To evaluate the efficacy and safety of glucosamine and chondroitin sulphate (CS), alone or in combination, as well as celecoxib and placebo o...

journal_title：Annals of the rheumatic diseases

authors： Sawitzke AD,Shi H,Finco MF,Dunlop DD,Harris CL,Singer NG,Bradley JD,Silver D,Jackson CG,Lane NE,Oddis CV,Wolfe F,Lisse J,Furst DE,Bingham CO,Reda DJ,Moskowitz RW,Williams HJ,Clegg DO

更新日期：2010-08-01 00:00:00

abstract：:Erosions on the triquetrum and pisiform are frequent in early rheumatoid arthritis and occur characteristically at 3 sites. (a) A shallow erosion on the proximal medial triquetral "bare" area is related to synovial proliferation at the margin of the radiocarpal cavity, although compressive forces from an adjacent long...

journal_title：Annals of the rheumatic diseases

authors： Resnick D

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SSc) is an autoimmune disease characterised by fibrosis of the skin and the internal organs. Except for anticentromere, antitopoisomerase I and antipolymerase III antibodies, there are no reliable circulating markers predicting susceptibility and internal organ complications. This study h...

journal_title：Annals of the rheumatic diseases

authors： van Bon L,Cossu M,Loof A,Gohar F,Wittkowski H,Vonk M,Roth J,van den Berg W,van Heerde W,Broen JC,Radstake TR

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Studies in rheumatoid arthritis (RA), osteoarthritis (OA) and mice with arthritis demonstrated tyrosine hydroxylase-positive (TH(+)) cells in arthritic synovium and parallel loss of sympathetic nerve fibres. The exact function of TH(+) cells and mode of TH induction are not known. METHODS:Synovial cells of ...

journal_title：Annals of the rheumatic diseases

authors： Jenei-Lanzl Z,Capellino S,Kees F,Fleck M,Lowin T,Straub RH

更新日期：2015-02-01 00:00:00

abstract：:The clinical and laboratory data for an 8 year old girl with abdominal pain as a presenting manifestation of acute rheumatic fever are reported. An abdominal investigation with ultrasonography carried out at the same time showed free peritoneal fluid. These findings support the proposal that the abdominal pain classic...

journal_title：Annals of the rheumatic diseases

authors： Picard E,Gedalia A,Benmeir P,Zucker N,Barki Y

更新日期：1992-03-01 00:00:00