Abstract:
PRIMARY OBJECTIVE:This paper examined the use of an atypical neuroleptic medication, risperidone, in reducing the excessive motor activity of an adolescent with an anoxic brain injury following cardiac arrest from a lightning strike. Lower extremity restlessness caused the patient to develop skin breakdown and interfered with healing of existing burns. RESEARCH DESIGN:Single-blind, placebo-controlled single-subject experimental design. EXPERIMENTAL INTERVENTION:Escalating doses of risperidone up to 1 mg and in combination with methylphenidate (10 mg) and amantidine (100 mg). MAIN OUTCOMES AND RESULTS:The patient demonstrated a reduction in restlessness in response to the use of risperidone, which permitted wound healing. The addition of methlphenidate to risperidone led to a slight increase in attention to task. CONCLUSIONS:The use of the atypical neuroleptic medication, risperidone, may be considered as part of the armamentarium available to physicians treating restlessness in severe brain injuries.
journal_name
Brain Injjournal_title
Brain injuryauthors
Silver BV,Collins L,Zidek KAdoi
10.1080/0269905021000013192subject
Has Abstractpub_date
2003-03-01 00:00:00pages
237-44issue
3eissn
0269-9052issn
1362-301Xpii
AR06HRF95Y9PKA1Ajournal_volume
17pub_type
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