Colon and rectal surgery without mechanical bowel preparation: a randomized prospective trial.

Abstract:

OBJECTIVE:To assess whether elective colon and rectal surgery can be safely performed without preoperative mechanical bowel preparation. SUMMARY BACKGROUND DATA:Mechanical bowel preparation is routinely done before colon and rectal surgery, aimed at reducing the risk of postoperative infectious complications. However, in cases of penetrating colon trauma, primary colonic anastomosis has proven to be safe even though the bowel is not prepared. METHODS:Patients undergoing elective colon and rectal resections with primary anastomosis were prospectively randomized into two groups. Group A had mechanical bowel preparation with polyethylene glycol before surgery, and group B had their surgery without preoperative mechanical bowel preparation. Patients were followed up for 30 days for wound, anastomotic, and intra-abdominal infectious complications. RESULTS:Three hundred eighty patients were included in the study, 187 in group A and 193 in group B. Demographic characteristics, indications for surgery, and type of surgical procedure did not significantly differ between the two groups. Colo-colonic or colorectal anastomosis was performed in 63% of the patients in group A and 66% in group B. There was no difference in the rate of surgical infectious complications between the two groups. The overall infectious complications rate was 10.2% in group A and 8.8% in group B. Wound infection, anastomotic leak, and intra-abdominal abscess occurred in 6.4%, 3.7%, and 1.1% versus 5.7%, 2.1%, and 1%, respectively. CONCLUSIONS:These results suggest that elective colon and rectal surgery may be safely performed without mechanical preparation.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Zmora O,Mahajna A,Bar-Zakai B,Rosin D,Hershko D,Shabtai M,Krausz MM,Ayalon A

doi

10.1097/01.SLA.0000055222.90581.59

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

363-7

issue

3

eissn

0003-4932

issn

1528-1140

journal_volume

237

pub_type

临床试验,杂志文章,随机对照试验
  • Multiple cutaneous malignant melanomas with features of primary melanoma.

    abstract::A case report and review of the literature regarding multiple primary melanomas, and a discussion of the histologic differentiation between cutaneous primary melanomas and dermal metastases are presented. This report concerns a patient who, following wide surgical resection of a 1.3 mm thick primary melanoma with sate...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198102000-00021

    authors: Unger SW,Wanebo HJ,Cooper PH

    更新日期:1981-02-01 00:00:00

  • Blunt carotid artery trauma: report of two cases and review of the literature.

    abstract::Blunt carotid artery trauma is uncommon but has been associated with severe, permanent neurologic deficits in 42% and mortality in 30% of 96 patients previously reported in the English literature. Since neurologic symptoms characteristically develop only after a latent interval and since physical evidence of significa...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198003000-00014

    authors: Krajewski LP,Hertzer NR

    更新日期:1980-03-01 00:00:00

  • Bilateral breast cancer. Risk reduction by contralateral biopsy.

    abstract::Although survival from primary breast cancer has improved with earlier diagnosis and treatment, the management of the opposite breast is still in question. The risk factors for bilaterality are known, and preoperative mammography is occasionally helpful, but identification of early second breast cancer is very limited...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198506000-00001

    authors: Wanebo HJ,Senofsky GM,Fechner RE,Kaiser D,Lynn S,Paradies J

    更新日期:1985-06-01 00:00:00

  • Laparoscopic Heller myotomy versus endoscopic balloon dilatation for the treatment of achalasia: a network meta-analysis.

    abstract:OBJECTIVE:Comparison of short- and long-term effects after laparoscopic Heller myotomy (LHM) and endoscopic balloon dilation (EBD) considering the need for retreatment. BACKGROUND:Previously published studies have indicated that LHM is the most effective treatment for Achalasia. In contrast to that a recent randomized...

    journal_title:Annals of surgery

    pub_type: 杂志文章,meta分析

    doi:10.1097/SLA.0000000000000212

    authors: Schoenberg MB,Marx S,Kersten JF,Rösch T,Belle S,Kähler G,Vassiliou MC,Lüth S,von Renteln D

    更新日期:2013-12-01 00:00:00

  • Mitral replacement: clinical experience with a ball-valve prosthesis. Twenty-five years later.

    abstract::The purpose of this report is to review the results of mitral valve replacement since a first report in the Annals of Surgery in 1961, in order to determine the relative importance of new valve designs versus other surgical variables. The continued use of the silastic ball valve in its 1966 configuration (Model 6120),...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198509000-00016

    authors: Cobanoglu A,Grunkemeier GL,Aru GM,McKinley CL,Starr A

    更新日期:1985-09-01 00:00:00

  • Hospital length of stay after admission for traumatic injury in Canada: a multicenter cohort study.

    abstract:OBJECTIVE:To describe acute care length of stay (LOS) over all consecutive hospitalizations for the injury and according to level of care [intensive care unit (ICU), intermediate care, general ward], compare observed and expected LOS, and identify predictors of LOS. BACKGROUND:Prolonged LOS has important consequences ...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000000624

    authors: Moore L,Stelfox HT,Turgeon AF,Nathens A,Bourgeois G,Lapointe J,Gagné M,Lavoie A

    更新日期:2014-07-01 00:00:00

  • Metabolic surgery for non-obese type 2 diabetes: incretins, adipocytokines, and insulin secretion/resistance changes in a 1-year interventional clinical controlled study.

    abstract:OBJECTIVE:To compare duodenal-jejunal bypass (DJB) with standard medical care in nonobese patients with type 2 diabetes and evaluate surgically induced endocrine and metabolic changes. METHODS:Eighteen patients submitted to a DJB procedure met the following criteria: overweight, diabetes diagnosis less than 15 years, ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182592c62

    authors: Geloneze B,Geloneze SR,Chaim E,Hirsch FF,Felici AC,Lambert G,Tambascia MA,Pareja JC

    更新日期:2012-07-01 00:00:00

  • What Promotes Surgeon Practice Change? A Scoping Review of Innovation Adoption in Surgical Practice.

    abstract:OBJECTIVE:The goal of this scoping review was to summarize the literature on facilitators and barriers to surgical practice change. This information can inform research to implement best practices and evaluate new surgical innovations. BACKGROUND:In an era of accelerated innovations, surgeons face the difficult decisi...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004355

    authors: Arroyo NA,Gessert T,Hitchcock M,Tao M,Smith CD,Greenberg C,Fernandes-Taylor S,Francis DO

    更新日期:2020-08-26 00:00:00

  • Early effects of catecholamine therapy on mucosal integrity, intestinal blood flow, and oxygen metabolism in porcine endotoxin shock.

    abstract:OBJECTIVE:To determine the early effects of therapy of endotoxin (ET) shock with epinephrine, norepinephrine, or dopexamine on splanchnic circulation, oxygen metabolism, sigmoid mucosal pHi, bacterial translocation, and morphologic integrity of the ileal, colonic, and sigmoid mucosa. SUMMARY BACKGROUND DATA:Conflictin...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199808000-00014

    authors: Sautner T,Wessely C,Riegler M,Sedivy R,Götzinger P,Losert U,Roth E,Jakesz R,Függer R

    更新日期:1998-08-01 00:00:00

  • Proximal splenorenal shunts for extrahepatic portal venous obstruction in children.

    abstract:OBJECTIVE:The results of proximal splenorenal shunts done in children with extrahepatic portal venous obstruction were evaluated. SUMMARY BACKGROUND DATA:Extrahepatic portal venous obstruction, a common cause of portal hypertension in children in India, is being treated increasingly by endoscopic sclerotherapy instead...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199402000-00011

    authors: Prasad AS,Gupta S,Kohli V,Pande GK,Sahni P,Nundy S

    更新日期:1994-02-01 00:00:00

  • The influence of injury severity on complication rates after primary closure or colostomy for penetrating colon trauma.

    abstract::The management of penetrating colon injury has been frequently debated in the literature, yet few reports have evaluated primary closure versus diverting colostomy in similarly injured patients. Diverting colostomy is the standard of care when mucosal penetration is present, but primary closure in civilian practice ha...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198904000-00009

    authors: Nelken N,Lewis F

    更新日期:1989-04-01 00:00:00

  • Occlusion of the pancreatic duct versus pancreaticojejunostomy: a prospective randomized trial.

    abstract:OBJECTIVE:Using a prospective randomized study to assess postoperative morbidity and pancreatic function after pancreaticoduodenectomy with pancreaticojejunostomy and duct occlusion without pancreaticojejunostomy. SUMMARY BACKGROUND DATA:Postoperative complications after pancreaticoduodenectomy are largely due to leak...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000658-200210000-00004

    authors: Tran K,Van Eijck C,Di Carlo V,Hop WC,Zerbi A,Balzano G,Jeekel H

    更新日期:2002-10-01 00:00:00

  • The American Medical Association's Section on Surgery: The Beginnings of the Organization, Professionalization, and Specialization of Surgery in the United States.

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    journal_title:Annals of surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/SLA.0000000000001635

    authors: Rutkow I

    更新日期:2017-01-01 00:00:00

  • Endovascular repair of abdominal aortic aneurysms: risk stratified outcomes.

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    pub_type: 杂志文章

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    authors: Chaikof EL,Lin PH,Brinkman WT,Dodson TF,Weiss VJ,Lumsden AB,Terramani TT,Najibi S,Bush RL,Salam AA,Smith RB 3rd

    更新日期:2002-06-01 00:00:00

  • Single administration of thrombopoietin prevents progression of liver fibrosis and promotes liver regeneration after partial hepatectomy in cirrhotic rats.

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    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31818584c7

    authors: Murata S,Hashimoto I,Nakano Y,Myronovych A,Watanabe M,Ohkohchi N

    更新日期:2008-11-01 00:00:00

  • A personal experience with 100 consecutive total colectomies and straight ileoanal endorectal pull-throughs for benign disease of the colon and rectum in children and adults.

    abstract::In 1974 total colectomy and ileoanal straight endorectal pull-through (ERPT) were first used at our institution for the definitive management of total colonic Hirschsprung's disease in infants and children. Early success with this operation encouraged us to use this procedure in children and adults with ulcerative col...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199009000-00002

    authors: Coran AG

    更新日期:1990-09-01 00:00:00

  • Management of external gastrointestinal fistulas.

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    pub_type: 杂志文章

    doi:10.1097/00000658-197810000-00003

    authors: Reber HA,Roberts C,Way LW,Dunphy JE

    更新日期:1978-10-01 00:00:00

  • The role of vascular laboratory criteria in the selection of patients for lower extremity amputation.

    abstract::We evaluated clinical and vascular laboratory data on 126 patients with below-knee or forefoot amputation. Vascular laboratory examination included Doppler systolic blood pressure and arterial wave form analysis using the segmental plethysmograph. Fifty-four patients had below-knee amputation. A calf systolic pressure...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198204000-00014

    authors: Nicholas GG,Myers JL,DeMuth WE Jr

    更新日期:1982-04-01 00:00:00

  • The natural history of hepatic metastases from colorectal cancer. A comparison with resective treatment.

    abstract::Five-year survival after resection of hepatic metastases from colorectal cancer is 25%. Although resection palliates some patients who do not live that long, 50% of patients so treated are not helped at all. Until ignorance of a cancer's real stage is resolved by improved techniques, the evaluation and choice of thera...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198405000-00002

    authors: Wagner JS,Adson MA,Van Heerden JA,Adson MH,Ilstrup DM

    更新日期:1984-05-01 00:00:00

  • One thousand liver transplants. The lessons learned.

    abstract:OBJECTIVE:To evaluate the first 1000 liver transplants performed at UCLA Medical Center to determine factors responsible for improved results. SUMMARY BACKGROUND DATA:Liver transplant has evolved impressively since the first case was performed in 1963. The 1980s have highlighted this progress with the development of b...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199405000-00007

    authors: Busuttil RW,Shaked A,Millis JM,Jurim O,Colquhoun SD,Shackleton CR,Nuesse BJ,Csete M,Goldstein LI,McDiarmid SV

    更新日期:1994-05-01 00:00:00

  • Embryonic Origin of Primary Colon Cancer Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colon Cancer Liver Metastases.

    abstract:BACKGROUND:The aim of this study was to determine the prognostic value of embryonic origin in patients undergoing resection after chemotherapy for colon cancer liver metastases (CCLM). METHODS:We identified 725 patients with primary colon cancer and known RAS mutation status who underwent hepatic resection after preop...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002087

    authors: Yamashita S,Brudvik KW,Kopetz SE,Maru D,Clarke CN,Passot G,Conrad C,Chun YS,Aloia TA,Vauthey JN

    更新日期:2018-03-01 00:00:00

  • Immune RNA therapy for renal cell carcinoma: survival and immunologic monitoring.

    abstract::Twenty patients with metastatic renal cell carcinoma and nine patients with minimal residual disease (MRD) but at high risk for recurrence following nephrectomy received weekly four milligram intradermal injections of purified RNA extracted from lymphoid organs of sheep immunized with human renal cell carcinoma. Eight...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197710000-00007

    authors: Ramming KP,deKernion JB

    更新日期:1977-10-01 00:00:00

  • Intestinal radioprotection by vitamin E (alpha-tocopherol).

    abstract:OBJECTIVES:The major objective of this study was to test vitamin E as a potential radioprotectant for the small bowel of the rat. SUMMARY BACKGROUND DATA:Vitamin E has previously been shown to provide radioprotection in animal models: increased survival after whole-body irradiation, diminished absorptive malfunction, ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199522240-00008

    authors: Felemovicius I,Bonsack ME,Baptista ML,Delaney JP

    更新日期:1995-10-01 00:00:00

  • Subclassification of Microscopic Vascular Invasion in Hepatocellular Carcinoma.

    abstract:OBJECTIVE:To investigate whether subclassification of microscopic vascular invasion (MiVI) affects the long-term outcome after curative surgical resection or liver transplantation (LT) in patients with hepatocellular carcinoma (HCC). SUMMARY OF BACKGROUND DATA:The most important factor for TNM staging in HCC is MiVI, ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003781

    authors: Kang I,Jang M,Lee JG,Han DH,Joo DJ,Kim KS,Kim MS,Choi JS,Kim SI,Park YN,Choi GH

    更新日期:2020-01-14 00:00:00

  • The Carbon Footprint of Surgical Operations: A Systematic Review.

    abstract:OF BACKGROUND DATA AND OBJECTIVES:Operating theatres are typically the most resource-intensive area of a hospital, 3-6 times more energy-intensive than the rest of the hospital and a major contributor of waste. The primary objective of this systematic review was to evaluate existing literature calculating the carbon fo...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003951

    authors: Rizan C,Steinbach I,Nicholson R,Lillywhite R,Reed M,Bhutta MF

    更新日期:2020-12-01 00:00:00

  • Intermittent Pneumatic Compression in Addition to Standard Prophylaxis of Postoperative Venous Thromboembolism in Extremely High-risk Patients (IPC SUPER): A Randomized Controlled Trial.

    abstract:OBJECTIVE:To assess the efficacy of adjunctive IPC to standard prophylaxis of postoperative VTE in patients at extremely high-risk. SUMMARY OF BACKGROUND DATA:The standard prophylaxis for postoperative VTE is insufficient in extremely high-risk patients. It is unclear whether an adjunctive use of IPC would result in a...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004556

    authors: Lobastov K,Sautina E,Alencheva E,Bargandzhiya A,Schastlivtsev I,Barinov V,Laberko L,Rodoman G,Boyarintsev V

    更新日期:2020-11-12 00:00:00

  • The effect of mesh removal and selective neurectomy on persistent postherniotomy pain.

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    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/SLA.0b013e31818eec49

    authors: Aasvang EK,Kehlet H

    更新日期:2009-02-01 00:00:00

  • Comparison of surgical outcomes between teaching and nonteaching hospitals in the Department of Veterans Affairs.

    abstract:OBJECTIVE:To determine whether the investment in postgraduate education and training places patients at risk for worse outcomes and higher costs than if medical and surgical care was delivered in nonteaching settings. SUMMARY BACKGROUND DATA:The Veterans Health Administration (VA) plays a major role in the training of...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200109000-00011

    authors: Khuri SF,Najjar SF,Daley J,Krasnicka B,Hossain M,Henderson WG,Aust JB,Bass B,Bishop MJ,Demakis J,DePalma R,Fabri PJ,Fink A,Gibbs J,Grover F,Hammermeister K,McDonald G,Neumayer L,Roswell RH,Spencer J,Turnage RH,V

    更新日期:2001-09-01 00:00:00

  • Exclusion of nonisolated splenic vein in distal splenorenal shunt for prevention of portal malcirculation.

    abstract::In an attempt to prevent portoprival malcirculation after distal splenorenal shunt (DSRS), a splenic hilar renal shunt (HRS) with proximal flush ligation of splenic vein was designed. To accomplish this procedure, two methods were compared: HRS alone (Group A) and HRS plus proximal flush ligation of the splenic vein (...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198412000-00007

    authors: Inokuchi K,Beppu K,Koyanagi N,Nagamine K,Hashizume M,Sugimachi K

    更新日期:1984-12-01 00:00:00

  • Release of cholecystokinin and gallbladder contraction before and after gastrectomy.

    abstract::The contraction of the gallbladder by ultrasonography and release of cholecystokinin (CCK) by specific radioimmunoassay in response to the ingestion of oral fatty meal before and 1 month after gastrectomy in five patients with early gastric cancer was studied. Before gastrectomy, basal concentrations of CCK (13.4 +/- ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:

    authors: Inoue K,Fuchigami A,Hosotani R,Kogire M,Huang YS,Miyashita T,Suzuki T,Tsuda K,Seino Y,Rayford PL

    更新日期:1987-01-01 00:00:00