Release of cholecystokinin and gallbladder contraction before and after gastrectomy.

Abstract:

:The contraction of the gallbladder by ultrasonography and release of cholecystokinin (CCK) by specific radioimmunoassay in response to the ingestion of oral fatty meal before and 1 month after gastrectomy in five patients with early gastric cancer was studied. Before gastrectomy, basal concentrations of CCK (13.4 +/- 2.3 pmol/L) rose significantly to a maximum of 23.3 +/- 3.6 pmol/L at 20 minutes after ingestion of oral fatty meal, and remained significantly elevated during the study. Gallbladder contraction began as CCK concentrations rose, demonstrating significant correlation with plasma CCK. One month after gastrectomy, CCK showed a rapid and greater response to the ingestion of fatty meal, attaining a maximum of 53.7 +/- 7.3 pmol/L at 10 minutes, then gradually falling to basal level. The maximal contraction of the gallbladder after gastrectomy was almost the same as before gastrectomy (62.7 +/- 4.0% of original area), showing a significant correlation with plasma CCK, but refilling of the gallbladder was induced earlier with corresponding reduction of plasma CCK. Simultaneous measurement of plasma concentrations of pancreatic polypeptide revealed a fairly similar response to plasma CCK before and after gastrectomy. The release of CCK is the chief mechanism by which the ingestion of a fatty meal causes contraction of the gallbladder even after gastrectomy as well as before gastrectomy.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Inoue K,Fuchigami A,Hosotani R,Kogire M,Huang YS,Miyashita T,Suzuki T,Tsuda K,Seino Y,Rayford PL

subject

Has Abstract,Author List Incomplete

pub_date

1987-01-01 00:00:00

pages

27-32

issue

1

eissn

0003-4932

issn

1528-1140

journal_volume

205

pub_type

杂志文章
  • Factors Associated With Recurrence and Survival in Lymph Node-negative Gastric Adenocarcinoma: A 7-Institution Study of the US Gastric Cancer Collaborative.

    abstract:OBJECTIVES:To determine pathologic features associated with recurrence and survival in patients with lymph node-negative gastric adenocarcinoma. STUDY DESIGN:Multi-institutional retrospective analysis. BACKGROUND:Lymph node status is among the most important predictors of recurrence after gastrectomy for gastric aden...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000001084

    authors: Jin LX,Moses LE,Squires MH 3rd,Poultsides GA,Votanopoulos K,Weber SM,Bloomston M,Pawlik TM,Hawkins WG,Linehan DC,Strasberg SM,Schmidt C,Worhunsky DJ,Acher AW,Cardona K,Cho CS,Kooby DA,Levine E,Winslow ER,Saunders ND

    更新日期:2015-12-01 00:00:00

  • Pancreatic Cancer Surgery: The New R-status Counts.

    abstract:OBJECTIVE:To assess the relevance of resection margin status for survival outcome after resection and adjuvant therapy for pancreatic cancer. BACKGROUND:The definitions for R0 and R1 margin status after resection for pancreatic cancer are controversial. The strict definition of R0 requiring a 1 mm tumor-free margin is...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001731

    authors: Strobel O,Hank T,Hinz U,Bergmann F,Schneider L,Springfeld C,Jäger D,Schirmacher P,Hackert T,Büchler MW

    更新日期:2017-03-01 00:00:00

  • Catecholamines: mediator of the hypermetabolic response to thermal injury.

    abstract::Hypermetabolism characterizes the metabolic response to thermal injury and the extent of energy production is positively related to the rate of urinary catecholamine excretion. Alpha and beta adrenergic blockade decreased metabolism from 69.6 +/- 5.3 Kcal/m(2)/hr to 57.4 +/- 5.2 (p < 0.01), and infusion of 6 microgm e...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197410000-00031

    authors: Wilmore DW,Long JM,Mason AD Jr,Skreen RW,Pruitt BA Jr

    更新日期:1974-10-01 00:00:00

  • Pylorus Resection Does Not Reduce Delayed Gastric Emptying After Partial Pancreatoduodenectomy: A Blinded Randomized Controlled Trial (PROPP Study, DRKS00004191).

    abstract:OBJECTIVES:The aim of this study was to investigate the effect of pylorus resection on postoperative delayed gastric emptying (DGE) after partial pancreatoduodenectomy (PD). BACKGROUND:PD is the standard treatment for tumors of the pancreatic head. Preservation of the pylorus has been widely accepted as standard proce...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000002480

    authors: Hackert T,Probst P,Knebel P,Doerr-Harim C,Bruckner T,Klaiber U,Werner J,Schneider L,Michalski CW,Strobel O,Ulrich A,Diener MK,Büchler MW

    更新日期:2018-06-01 00:00:00

  • Academic Advancement in Global Surgery: Appointment, Promotion, and Tenure: Recommendations From the American Surgical Association Working Group on Global Surgery.

    abstract::: There is growing interest in global surgery among US academic surgical departments. As academic global surgery is a relatively new field, departments may have minimal experience in evaluation of faculty contributions and how they integrate into the existing academic paradigm for promotion and tenure. The American Su...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003480

    authors: Wren SM,Balch CM,Doherty GM,Finlayson SR,Kauffman GL,Kibbe MR,Haider AH,Minter RM,Mock C,Muguti GI,Numann PJ,Olutoye OO,Roy N,Weigel RJ

    更新日期:2020-02-01 00:00:00

  • Evidence-based gallbladder cancer staging: changing cancer staging by analysis of data from the National Cancer Database.

    abstract:BACKGROUND:A recent revision of the American Joint Committee on Cancer (AJCC) staging for gallbladder cancer (6th Edition) involved some major changes. Most notably, T2N0M0 tumors were moved from stage II to stage IB; T3N1M0 disease was moved from stage III to stage IIB; and T4NxM0 (x = any) tumors were moved from stag...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000219737.81943.4e

    authors: Fong Y,Wagman L,Gonen M,Crawford J,Reed W,Swanson R,Pan C,Ritchey J,Stewart A,Choti M

    更新日期:2006-06-01 00:00:00

  • Ultrasound-guided radiofrequency-assisted segmental liver resection: a new technique.

    abstract::Segmental hepatectomy is appealing for several reasons including preservation of liver parenchyma, reduction of intraoperative blood loss, and blood replacement by dividing tissues along the anatomic planes. A simple technique guided by intraoperative ultrasound is described here using radio-frequency energy to create...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181b0c38a

    authors: Curro G,Bartolotta M,Barbera A,Jiao L,Habib N,Navarra G

    更新日期:2009-08-01 00:00:00

  • Perforated stress ulcer in infants: a silent threat.

    abstract::Stress ulcer has become an important clinical entity and its two major complications--bleeding and perforation--are among the most baffling problems, in terms of management, in clinical practice. Perforation, though the less common of the two, is perhaps the most formidable particularly when this occurs in a very sick...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197912000-00006

    authors: Adeyemi SD,Ein SH,Simpson JS

    更新日期:1979-12-01 00:00:00

  • Cholangitis with acute renal failure: priorities in therapeutics.

    abstract::Obstructive cholangitis with acute renal failure is a dramatic syndrome which merits individual definition. Twenty-one patients with acute suppurative cholangitis complicated by rapidly developing renal insufficiency were studied, and the severity of the renal failure, an acute interstitial tubulopathy, bore no signif...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197506000-00022

    authors: Bismuth H,Kuntziger H,Corlette MB

    更新日期:1975-06-01 00:00:00

  • The value of thymectomy in myasthenia gravis: a computer-assisted matched study.

    abstract::In the absence of a prospective randomized study of patients treated conservatively or with thymectomy, a computer-assisted retrospective matches study was devised. Of 563 patients treated for myasthenia gravis without thymoma up to 1965, 104 had thymectomy. With computer assistance, each surgical patient was matched ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197610000-00008

    authors: Buckingham JM,Howard FM Jr,Bernatz PE,Payne WS,Harrison EG Jr,O'Brien PC,Weiland LH

    更新日期:1976-10-01 00:00:00

  • Functional Trajectories Before and After Major Surgery in Older Adults.

    abstract:OBJECTIVES:We hypothesized that distinct sets of functional trajectories can be identified in the year before and after major surgery, with unique transition probabilities from pre to postsurgical functional trajectories, and that outcomes would be better among participants undergoing elective versus nonelective surger...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002659

    authors: Stabenau HF,Becher RD,Gahbauer EA,Leo-Summers L,Allore HG,Gill TM

    更新日期:2018-12-01 00:00:00

  • Recurrent carotid artery stenosis following endarterectomy.

    abstract::Spectral analysis was used to examine 257 carotid arteries in 227 patients who had undergone carotid endarterectomy at 1, 3, 6, and 12 months after surgery and annually thereafter. Routine intraoperative completion angiography ensured that the operations were technically satisfactory. Postoperative restenoses were ide...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198407000-00013

    authors: Thomas M,Otis SM,Rush M,Zyroff J,Dilley RB,Bernstein EF

    更新日期:1984-07-01 00:00:00

  • Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible?

    abstract:OBJECTIVE:To determine long-term survival after pancreatoduodenectomy for pancreatic ductal adenocarcinoma and to identify clinical factors associated with long-term survival. SUMMARY BACKGROUND DATA:The prognosis for long-term survival even after potentially curative resection for pancreatic adenocarcinoma is thought...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181613142

    authors: Schnelldorfer T,Ware AL,Sarr MG,Smyrk TC,Zhang L,Qin R,Gullerud RE,Donohue JH,Nagorney DM,Farnell MB

    更新日期:2008-03-01 00:00:00

  • Can CT-PET and Endoscopic Assessment Post-Neoadjuvant Chemoradiotherapy Predict Residual Disease in Esophageal Cancer?

    abstract:OBJECTIVE:The aim of this study is to assess CT-PET and endoscopic assessment postneoadjuvant chemoradiotherapy (nCRT) in predicting complete pathologic response (pCR) in locally advanced esophageal cancer (LAEC). DESIGN:A prospective cohort study. BACKGROUND:nCRT is increasingly standard of care in LAEC, with pCR a ...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001902

    authors: Heneghan HM,Donohoe C,Elliot J,Ahmed Z,Malik V,Ravi N,Reynolds JV

    更新日期:2016-11-01 00:00:00

  • Villous tumors of the duodenum.

    abstract::Records of 32 patients with 34 villous and tubulovillous adenomas of the duodenum, treated at the Cleveland Clinic over the past 21 years, were reviewed. Twenty-two patients (69%) had complete resection of the adenoma; the incidence of malignancy was 47%. Five patients underwent a Whipple procedure; 4 patients had seg...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198803000-00002

    authors: Galandiuk S,Hermann RE,Jagelman DG,Fazio VW,Sivak MV

    更新日期:1988-03-01 00:00:00

  • The Linton splenorenal shunt in the management of the bleeding complications of portal hypertension.

    abstract::This report describes 140 cases in which Linton splenorenal shunts were performed for the management of the complications of portal hypertension by a large number of surgeons in a single hospital. There was a history of variceal bleeding in 130. Using the Childs designation to reflect hepatic functional reserve, the o...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198212001-00008

    authors: Ottinger LW

    更新日期:1982-12-01 00:00:00

  • Significantly increased pregnancy rates after laparoscopic restorative proctocolectomy: a cross-sectional study.

    abstract:OBJECTIVE:To assess the impact of a laparoscopic approach on female fecundity in ileoanal pouch surgery. BACKGROUND:Restorative proctocolectomy with ileal pouch anal anastomosis (IPAA) is associated with tubal factor infertility in female patients. Different studies showed less adhesion formation after laparoscopic co...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/SLA.0b013e318250caa9

    authors: Bartels SA,DʼHoore A,Cuesta MA,Bensdorp AJ,Lucas C,Bemelman WA

    更新日期:2012-12-01 00:00:00

  • The comparative influence of prophylactic antibiotics on the prothrombin response to warfarin in the postoperative prosthetic cardiac valve patient. Cefamandole, cefazolin, vancomycin.

    abstract::A prospective randomized trial was conducted comparing the effect of three antibiotics: cefamandole (CM), cefazolin (CZ), and vancomycin (V), used as prophylaxis for prosthetic valve surgery, on the prothrombin (PT) response to warfarin (W) on the third day of anticoagulant therapy. Twenty patients, with normal preope...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000658-198708000-00007

    authors: Angaran DM,Dias VC,Arom KV,Northrup WF,Kersten TG,Lindsay WG,Nicoloff DM

    更新日期:1987-08-01 00:00:00

  • Fas and Fas-ligand expression in human pancreatic cancer.

    abstract:OBJECTIVE:To investigate Fas and FasL expression in pancreatic tissues and cultured pancreatic cancer cell lines, and to assess the ability of anti-Fas antibodies to induce apoptosis. SUMMARY BACKGROUND DATA:Activation of the Fas receptor by Fas-ligand (FasL) results in apoptosis, and dysregulation of this pathway may...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-200003000-00010

    authors: Kornmann M,Ishiwata T,Kleeff J,Beger HG,Korc M

    更新日期:2000-03-01 00:00:00

  • The potential of organizations of fee-for-service physicians for achieving significant decreases in hospitalization.

    abstract::Because hospitalization is a key factor in controlling health care costs and because fee-for-service remains the predominant mode of physician payment, a study was undertaken of the hospitalization experiences of open panel fee-for-service health maintenance organizations (IPA-HMOs) and Foundations for Medical Care (F...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197709000-00017

    authors: Edgahl RH,Taft CH,Friedland J,Linde K

    更新日期:1977-09-01 00:00:00

  • Anticatabolic effects of avoiding preoperative fasting by intravenous hypocaloric nutrition: a randomized clinical trial.

    abstract:OBJECTIVE:We tested the hypothesis that the avoidance of preoperative fasting by hypocaloric nutrition attenuates protein catabolism after surgery. SUMMARY BACKGROUND DATA:Prolonged fasting before major abdominal procedures has been demonstrated to accentuate the catabolic response to surgery. METHODS:Twenty-two pati...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0b013e31818842d8

    authors: Schricker T,Meterissian S,Lattermann R,Adegoke OA,Marliss EB,Mazza L,Eberhart L,Carli F,Nitschman E,Wykes L

    更新日期:2008-12-01 00:00:00

  • Predictive Value of Endoscopic Features for a Complete Response After Chemoradiotherapy for Rectal Cancer.

    abstract:OBJECTIVE AND BACKGROUND:Watch-and-wait approach in rectal cancer relies on the identification of a clinical complete response (CR) after neoadjuvant (chemo)radiotherapy. This is mainly performed by rectal examination, magnetic resonance imaging, and endoscopy. Endoscopy has been less well studied, and the objective of...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000003718

    authors: van der Sande ME,Maas M,Melenhorst J,Breukink SO,van Leerdam ME,Beets GL

    更新日期:2019-12-09 00:00:00

  • Is competency assessment at the specialist level achievable? A study for the national training programme in laparoscopic colorectal surgery in England.

    abstract:OBJECTIVES:To develop, validate, and implement a competency assessment tool (CAT) for technical surgical performance in the context of a summative assessment process for the National Training Programme in Laparoscopic Colorectal Surgery (NTP). BACKGROUND:The NTP is an educational initiative by the National Cancer Acti...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e318275b72a

    authors: Miskovic D,Ni M,Wyles SM,Kennedy RH,Francis NK,Parvaiz A,Cunningham C,Rockall TA,Gudgeon AM,Coleman MG,Hanna GB,National Training Programme in Laparoscopic Colorectal Surgery in England.

    更新日期:2013-03-01 00:00:00

  • Evaluation of Recurrence Risk After Curative Resection for Patients With Stage I to III Colorectal Cancer Using the Hazard Function: Retrospective Analysis of a Single-institution Large Cohort.

    abstract:OBJECTIVE:This study aimed to investigate transitions of recurrence hazard and peak recurrence time in patients with nonmetastatic CRC using the hazard function. SUMMARY OF BACKGROUND DATA:A postoperative surveillance period of 5 years is consistent across major guidelines for patients with nonmetastatic CRC, but surv...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004058

    authors: Kudose Y,Shida D,Ahiko Y,Nakamura Y,Sakamoto R,Moritani K,Tsukamoto S,Kanemitsu Y

    更新日期:2020-06-11 00:00:00

  • Explaining the Paradoxical Age-based Racial Disparities in Survival After Trauma: The Role of the Treating Facility.

    abstract:OBJECTIVE:The objective of our study was to determine if differences in outcomes at treating facilities can help explain these age-based racial disparities in survival after trauma. BACKGROUND:It has been previously demonstrated that racial disparities in survival after trauma are dependent on age. For patients younge...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000000809

    authors: Hicks CW,Hashmi ZG,Hui X,Velopulos C,Efron DT,Schneider EB,Cooper L,Haut ER,Cornwell EE 3rd,Haider AH

    更新日期:2015-07-01 00:00:00

  • Ultrasound in renal transplantation.

    abstract::Because of important differences in prognosis and treatment, prompt and accurate diagnosis of fever, decreasing function, and pain and tenderness around a renal allograft is crucial for differentiation between acute rejection and other post-operative conditions which may give a similar picture. Ultrasound examinations...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197704000-00012

    authors: Petrek J,Tilney NL,Smith EH,Williams JS,Vineyard GC

    更新日期:1977-04-01 00:00:00

  • Carcinoma of the ampulla of Vater: Review of 38 cases with emphasis on treatment and prognostic factors.

    abstract::Thirty-eight cases of carcinoma of the ampulla of Vater are presented. The diagnosis has been confirmed at laparatomy in all patients. Three operations were done, a pancreaticoduodenal resection in 23 patients, a biliary-enteric bypass in 7 patients and a biliary-enteric bypass plus excision of tumor in 8 patients. Th...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197604000-00002

    authors: Makipour H,Cooperman A,Danzi JT,Farmer RG

    更新日期:1976-04-01 00:00:00

  • What have we learned about primary liver transplantation under tacrolimus immunosuppression? Long-term follow-up of the first 1000 patients.

    abstract:OBJECTIVE:To summarize the long-term efficacy and safety of tacrolimus in orthotopic liver transplant (OLT) recipients, as well as to examine the factors that influence long-term morbidity and mortality rates. BACKGROUND:Tacrolimus (FK506, Prograf) was introduced as primary immunosuppression for primary liver transpla...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199909000-00016

    authors: Jain A,Reyes J,Kashyap R,Rohal S,Abu-Elmagd K,Starzl T,Fung J

    更新日期:1999-09-01 00:00:00

  • Significant contribution of the portal vein to blood flow through the common bile duct.

    abstract:OBJECTIVE:The aim of this study was to determine the contribution of the hepatic artery, gastroduodenal artery, and portal vein to the microvascular blood flow in the common bile duct (CBD). BACKGROUND:Biliary complications are a common cause of graft loss after liver transplantation. The occurrence is, partly, attrib...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31824714d0

    authors: Slieker JC,Farid WR,van Eijck CH,Lange JF,van Bommel J,Metselaar HJ,de Jonge J,Kazemier G

    更新日期:2012-03-01 00:00:00

  • The effect of sacral nerve modulation on cerebral evoked potential latency in fecal incontinence and constipation.

    abstract:OBJECTIVE:Influence of sacral nerve modulation (SNM) on cerebral somatosensory evoked potentials (SEP) was determined in patients with incontinence and constipation. BACKGROUND:Selection of patients with incontinence and constipation for SNM could be improved. METHODS:The latency (ms) of SEP induced by pudendal nerve...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3182196ff4

    authors: Giani I,Novelli E,Martina S,Clerico G,Luc AR,Trompetto M,Malaguti S,Nicholls J,Ganio E

    更新日期:2011-07-01 00:00:00