Abstract:
:Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger-mediated signaling events. Localization of the cAMP-dependent protein kinase (PKA) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). This study focused on recent advances that further our understanding of AKAPs, with particular emphasis on the bidirectional regulation of signaling events by AKAP signaling complexes and their contribution to the control of actin reorganization events.
journal_name
Diabetesjournal_title
Diabetesauthors
Alto N,Carlisle Michel JJ,Dodge KL,Langeberg LK,Scott JDdoi
10.2337/diabetes.51.2007.s385subject
Has Abstractpub_date
2002-12-01 00:00:00pages
S385-8eissn
0012-1797issn
1939-327Xjournal_volume
51 Suppl 3pub_type
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