Decrease in serum leptin after prolonged physical activity in men.

Abstract:

PURPOSE:This study was designed to determine whether serum leptin levels were affected by a 5-d military course after 3 wk of combat training. METHODS:26 male soldiers (mean age = 21 +/- 2 yr) were examined at the beginning of the training program and just at the end of the 5-d course. The combination of continuous heavy physical activity and sleep deprivation led to energy deficiency. Blood samples were analyzed for serum leptin, insulin, cortisol, adrenocorticotropin (ACTH), and testosterone; plasma was analyzed for free fatty acids (FFA), glycerol, glucose, and catecholamines. RESULTS:At the end of the 5-d course, there was a significant reduction in serum leptin (0.40 +/- 0.04 ng x mL(-1) versus 1.47 +/- 0.14 ng x mL(-1), < 0.001), i.e., a mean decrease of 67.00 +/- 3.75%. Plasma norepinephrine and dopamine rose significantly from 296 +/- 17 ng x L(-1) to 672 +/- 48 ng x L(-1) and 23 +/- 3 ng x L(-1) to 40 +/- 5 ng x L(-1) ( < 0.001 and < 0.01, respectively), whereas epinephrine remained unchanged. Serum concentrations of the anabolic hormone, insulin, fell from 31.17 +/- 3.03 microU x mL(-1) to 17.79 +/- 1.58 microU x mL(-1) ( < 0.001), whereas plasma FFA and glycerol were increased ( < 0.001, < 0.05, respectively). A statistically significant correlation appeared between the changes in leptin and insulin (r = 0.5306, < 0.01). Serum testosterone decreased significantly ( < 0.001), whereas serum cortisol, ACTH, and plasma glucose were unchanged at the end of the course. The training program had no significant effect on mean body mass index. CONCLUSION:A 4-wk strenuous military training program, which induced an energy deficiency, reduced serum leptin to a third of normal levels. The decrease in serum leptin was attributed to the exercise-induced elevation in catecholamines and hypoinsulinemia.

journal_name

Med Sci Sports Exerc

authors

Gomez-Merino D,Chennaoui M,Drogou C,Bonneau D,Guezennec CY

doi

10.1097/00005768-200210000-00010

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

1594-9

issue

10

eissn

0195-9131

issn

1530-0315

journal_volume

34

pub_type

杂志文章
  • Lactate exchange and removal abilities in rowing performance.

    abstract::The relationships between individual performance and lactate exchange and removal abilities were studies in 12 male rowers all subjected to three measurements on a rowing ergometer. An incremental exercise carried out to determine the maximal oxygen uptake (VO2max) and the corresponding maximal aerobic power (Pamax), ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-199703000-00016

    authors: Messonnier L,Freund H,Bourdin M,Belli A,Lacour JR

    更新日期:1997-03-01 00:00:00

  • Central and peripheral cardiovascular adaptations during a maximal cycle exercise in boys and men.

    abstract:PURPOSE:Stroke volume response to exercise depends on changes in cardiac filling, intrinsic myocardial contractility, and left ventricular afterload. The purpose of this study was to compare these responses during an upright cycle test performed until exhaustion in children and adults. METHODS:Stroke volume, cardiac o...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-200203000-00012

    authors: Nottin S,Vinet A,Stecken F,Nguyen LD,Ounissi F,Lecoq AM,Obert P

    更新日期:2002-03-01 00:00:00

  • Kinematic Mechanisms of How Power Training Improves Healthy Old Adults' Gait Velocity.

    abstract:INTRODUCTION:Slow gait predicts many adverse clinical outcomes in old adults, but the mechanisms of how power training can minimize the age-related loss of gait velocity is unclear. We examined the effects of 10 wk of lower extremity power training and detraining on healthy old adults' lower extremity muscle power and ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001082

    authors: Beijersbergen CM,Granacher U,Gäbler M,Devita P,Hortobágyi T

    更新日期:2017-01-01 00:00:00

  • Elite Distance Runners: A 45-Year Follow-up.

    abstract:PURPOSE:The present longitudinal study assessed cardiorespiratory capacity and running economy of Olympic athletes over several decades to measure changes in fitness in an elite group during aging. METHODS:Twenty-six male runners training for the 1968 Olympics were recruited. HR, V˙O2max, ventilation, and running econ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001407

    authors: Everman S,Farris JW,Bay RC,Daniels JT

    更新日期:2018-01-01 00:00:00

  • Effects of acute salbutamol inhalation on quadriceps force and fatigability.

    abstract:INTRODUCTION:Oral beta2-agonist administration improves muscle function in persons without asthma. We performed a double-blind, randomized, controlled crossover study to assess whether acute inhaled salbutamol administration improves muscle strength and fatigability in healthy moderately trained subjects. METHODS:Quad...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,随机对照试验

    doi:10.1249/MSS.0b013e31816b87aa

    authors: Decorte N,Verges S,Flore P,Guinot M,Wuyam B

    更新日期:2008-07-01 00:00:00

  • Sympathetic nerve activity to nonactive muscle of the exercising and nonexercising limb.

    abstract::The purpose of this study was to determine whether efferent sympathetic nerve activity is different to resting skeletal muscles from the exercising and nonexercising limb. MSNA was measured by microneurography in both legs (peroneal nerve) in six subjects during 2 min of unilateral isometric knee extension (IKE; 10-30...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Ray CA,Mark AL

    更新日期:1995-02-01 00:00:00

  • Prevention and treatment of injuries to runners.

    abstract::1) Many otherwise healthy runners are prevented from participating fully in their chosen endurance sport because of overuse injuries. 2) The most important risk factor for incurring an overuse injury is a training error, such as excessive mileage, sudden change in training distance or intensity, too much hard interval...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-199209001-00010

    authors: O'Toole ML

    更新日期:1992-09-01 00:00:00

  • Resistance to exercise-induced weight loss: compensatory behavioral adaptations.

    abstract::In many interventions that are based on an exercise program intended to induce weight loss, the mean weight loss observed is modest and sometimes far less than what the individual expected. The individual responses are also widely variable, with some individuals losing a substantial amount of weight, others maintainin...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:10.1249/MSS.0b013e31828ba942

    authors: Melanson EL,Keadle SK,Donnelly JE,Braun B,King NA

    更新日期:2013-08-01 00:00:00

  • The impact of metabolic stress on hormonal responses and muscular adaptations.

    abstract:PURPOSE:The purpose of this study was to examine the impact of exercise-induced metabolic stress on hormonal responses and chronic muscular adaptations. METHODS:We compared the acute and long-term effects of an "NR regimen" (no-rest regimen) and those of a "WR regimen" (regimen with rest period within a set). Twenty-s...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Goto K,Ishii N,Kizuka T,Takamatsu K

    更新日期:2005-06-01 00:00:00

  • Energy expenditure of walking and running: comparison with prediction equations.

    abstract:PURPOSE:This study established the published prediction equations for the energy expenditure of walking and running compared with the measured values. To make this comparison we first determined whether differences exist in energy expenditure for 1600 m of walking versus running, and whether energy expenditure differen...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000147584.87788.0e

    authors: Hall C,Figueroa A,Fernhall B,Kanaley JA

    更新日期:2004-12-01 00:00:00

  • Maximal anaerobic performance of the knee extensor muscles during growth.

    abstract::The extent of the growth changes in maximal work output during 10 s (MWO10), 30 s (MWO30), and 90 s (MWO90) of maximal repetitive knee flexions and extensions assessed on a modified Hydra-Gym machine was investigated in 84 boys and 83 girls, 9-19 yr of age. Body weight, fat mass and fat free mass by underwater weighin...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Saavedra C,Lagassé P,Bouchard C,Simoneau JA

    更新日期:1991-09-01 00:00:00

  • Physiological and performance responses to overtraining in elite judo athletes.

    abstract::To determine the effect of large and sudden increases in training volume on performance characteristics and the feasibility of using overtraining syndrome symptoms to monitor performance changes, 15 elite judo athletes were examined through 10 wk of training. Athletes performed their regular regimens of resistance (3 ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/00005768-199012000-00014

    authors: Callister R,Callister RJ,Fleck SJ,Dudley GA

    更新日期:1990-12-01 00:00:00

  • Performance at high pedaling cadences in well-trained cyclists.

    abstract:PURPOSE:This study was conducted to determine the effect of high pedaling cadences on maximal cycling power output (W(max)). METHODS:Nine well-trained cyclists performed a continuous, incremental cycle-ergometer test to exhaustion (25 W increases every 3 min) either at 80, 100, or 120 rpm on three different occasions....

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000218139.46166.ec

    authors: Mora-Rodriguez R,Aguado-Jimenez R

    更新日期:2006-05-01 00:00:00

  • Aerobic exercise and attention deficit hyperactivity disorder: brain research.

    abstract:PURPOSE:As adjuvant therapy for enhancing the effects of stimulants and thereby minimizing medication doses, we hypothesized that aerobic exercise might be an effective adjunctive therapy for enhancing the effects of methylphenidate on the clinical symptoms, cognitive function, and brain activity of adolescents with at...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,随机对照试验

    doi:10.1249/MSS.0000000000000373

    authors: Choi JW,Han DH,Kang KD,Jung HY,Renshaw PF

    更新日期:2015-01-01 00:00:00

  • Energy expenditure in adolescents during low intensity, leisure activities.

    abstract::We sought to determine how a stationary activity such as playing a stringed instrument may affect energy expenditure (EE) in adolescents. Using automated indirect calorimetry, we measured EE in eight adolescents (1 male, 7 females, 14.2 +/- 2.1 yr) while they each performed the following activities: watching televisio...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Horswill CA,Kien CL,Zipf WB

    更新日期:1995-09-01 00:00:00

  • Effects of Neuromuscular Electrical Stimulation in People with Spinal Cord Injury.

    abstract:INTRODUCTION:Muscle force production is usually impaired in people with spinal cord injury (SCI). The use of high-intensity neuromuscular electrical stimulation (NMES) strength training can help promote metabolically active lean muscle mass and, thus, increase muscle mass and improve physical health and quality of life...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0000000000001637

    authors: Bochkezanian V,Newton RU,Trajano GS,Blazevich AJ

    更新日期:2018-09-01 00:00:00

  • Subconcussive head impact biomechanics: comparing differing offensive schemes.

    abstract:PURPOSE:Recent literature suggests that subconcussive impacts may influence cognitive functioning across the life span. These effects are suggested to manifest as functional and possibly structural changes. Head impact biomechanics during American football have been characterized from the high school to professional le...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e3182798758

    authors: Martini D,Eckner J,Kutcher J,Broglio SP

    更新日期:2013-04-01 00:00:00

  • Aerobic fitness: I. Response of volume regulating hormones to head-down tilt.

    abstract::We investigated the relationship of aerobic fitness to the response of volume-regulating hormones to acute simulated microgravity. Six untrained (UT) and six endurance-trained (ET) healthy young males were studied in the head-down tilt (HDT) position of -6 degrees for 4 h. Peak oxygen uptake (VO2peak) and plasma volum...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Shi X,Squires WG,Williamson JW,Crandall CG,Chen JJ,Krock LP,Raven PB

    更新日期:1992-09-01 00:00:00

  • Cardiovascular drift is related to reduced maximal oxygen uptake during heat stress.

    abstract:INTRODUCTION/PURPOSE:This study investigated whether the progressive rise in heart rate (HR) and fall in stroke volume (SV) during prolonged, constant-rate, moderate-intensity exercise (cardiovascular drift, CVdrift) in a hot environment is associated with a reduction in VO(2max). METHODS:CVdrift was measured in nine ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000152731.33450.95

    authors: Wingo JE,Lafrenz AJ,Ganio MS,Edwards GL,Cureton KJ

    更新日期:2005-02-01 00:00:00

  • Resistance training during unweighting maintains muscle size and function in human calf.

    abstract:PURPOSE:A 20-d 6 degrees head-down tilt bed rest project was conducted to evaluate the effect of dynamic leg press and plantar flexion resistance training on muscle size and function in human plantar flexors (PF) throughout the prolonged bed rest. METHODS:Twelve healthy men participated in this study and were divided ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1249/01.MSS.0000058367.66796.35

    authors: Akima H,Ushiyama J,Kubo J,Tonosaki S,Itoh M,Kawakami Y,Fukuoka H,Kanehisa H,Fukunaga T

    更新日期:2003-04-01 00:00:00

  • Postexercise Hypotension after Heart Transplant: Water- versus Land-Based Exercise.

    abstract:PURPOSE:Heart transplant recipients (HTx) have a high prevalence of hypertension. Although exercise training promotes blood pressure (BP) reduction in HTx, the effects of a single exercise bout are unknown. Thus, we analyzed the acute effects of heated water-based exercise (HEx) versus land-based exercise (LEx) on ambu...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,随机对照试验

    doi:10.1249/MSS.0000000000000846

    authors: Castro RE,Guimarães GV,Da Silva JM,Bocchi EA,Ciolac EG

    更新日期:2016-05-01 00:00:00

  • Critical power: implications for determination of V˙O2max and exercise tolerance.

    abstract::For high-intensity muscular exercise, the time-to-exhaustion (t) increases as a predictable and hyperbolic function of decreasing power (P) or velocity (V ). This relationship is highly conserved across diverse species and different modes of exercise and is well described by two parameters: the "critical power" (CP or...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章,评审

    doi:10.1249/MSS.0b013e3181d9cf7f

    authors: Jones AM,Vanhatalo A,Burnley M,Morton RH,Poole DC

    更新日期:2010-10-01 00:00:00

  • Associations of body size and composition with physical activity in adolescent girls.

    abstract:PURPOSE:To examine whether components of body composition (size, fat mass, and fat-free mass) were related to physical activity. METHODS:A random sample of 60 eligible sixth grade girls at each of 36 schools (six schools per region and six regions in total sample); complete measurements on 1,553 girls. Physical activi...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000222846.27380.61

    authors: Lohman TG,Ring K,Schmitz KH,Treuth MS,Loftin M,Yang S,Sothern M,Going S

    更新日期:2006-06-01 00:00:00

  • Effect of strength training upon motoneuron excitability in man.

    abstract::Two healthy females and twelve healthy males, aged 19-24 yr, underwent strength training for periods of 9-21 wk. The muscles trained included extensor digitorum brevis (N = 3), soleus (N = 7), brachioradialis (N = 4), and the hypothenar muscles (N = 3). The effect of training on motoneuron excitability was measured as...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Sale DG,MacDougall JD,Upton AR,McComas AJ

    更新日期:1983-01-01 00:00:00

  • Physical activity and active commuting to elementary school.

    abstract:PURPOSE:This study was conducted to determine if fifth-grade students who walked or bicycled to school on a regular basis were more physically active than those that did not. METHODS:The sample consists of 219 fifth-grade students (10.3 +/- 0.6 yr, 44% male, 58% minority) from eight randomly selected urban and suburba...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000179102.17183.6b

    authors: Sirard JR,Riner WF Jr,McIver KL,Pate RR

    更新日期:2005-12-01 00:00:00

  • Compendium of physical activities: an update of activity codes and MET intensities.

    abstract::We provide an updated version of the Compendium of Physical Activities, a coding scheme that classifies specific physical activity (PA) by rate of energy expenditure. It was developed to enhance the comparability of results across studies using self-reports of PA. The Compendium coding scheme links a five-digit code t...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1097/00005768-200009001-00009

    authors: Ainsworth BE,Haskell WL,Whitt MC,Irwin ML,Swartz AM,Strath SJ,O'Brien WL,Bassett DR Jr,Schmitz KH,Emplaincourt PO,Jacobs DR Jr,Leon AS

    更新日期:2000-09-01 00:00:00

  • Exercise respiratory pattern in elite cyclists and sedentary subjects.

    abstract::We investigated the breath-by-breath pattern of ventilatory response to bicycle exercise in seven elite male cyclists (VO2max = 71.7 ml X min-1 X kg-1) and ten sedentary males (VO2max = 47.3 ml X min-1 X kg-1) to analyze differences in breathing patterns between individuals with normal and high exercise ventilations (...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:

    authors: Folinsbee LJ,Wallace ES,Bedi JF,Horvath SM

    更新日期:1983-01-01 00:00:00

  • Cardiovascular response of trained preadolescent boys to mental challenge.

    abstract:PURPOSE:To compare the cardiovascular reactivity response to mental challenge of aerobically trained and untrained preadolescent boys. METHODS:Heart rate (HR) and blood pressure, as well as stroke volume, total peripheral resistance, rate pressure product, and cardiac contractility response in 15 aerobically trained (...

    journal_title:Medicine and science in sports and exercise

    pub_type: 临床试验,杂志文章

    doi:10.1249/01.MSS.0000078935.78895.8E

    authors: Franks PW,Boutcher SH

    更新日期:2003-08-01 00:00:00

  • Modulation of immune response by the acute and chronic exposure to high altitude.

    abstract:PURPOSE:The chronic exposure at high altitude (HA) represents an ideal model for evaluating the in vivo effects of hypobaric hypoxia. Taking advantage of the EV-K2-CNR Pyramid, this study was designed to evaluate whether acute and chronic hypoxia differently modulates the in vivo immune responses. METHODS:The study in...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/01.mss.0000162688.54089.ce

    authors: Facco M,Zilli C,Siviero M,Ermolao A,Travain G,Baesso I,Bonamico S,Cabrelle A,Zaccaria M,Agostini C

    更新日期:2005-05-01 00:00:00

  • VO2 kinetics and performance in soccer players after intense training and inactivity.

    abstract:PURPOSE:The study's purpose was to examine the effects of a short-term period with intensified training or training cessation of trained soccer players on VO(2) kinetics at 75% maximal aerobic speed, oxidative enzymes, and performance in repeated high-intensity exercise. METHODS:After the last match of the season, 18 ...

    journal_title:Medicine and science in sports and exercise

    pub_type: 杂志文章

    doi:10.1249/MSS.0b013e318211c01a

    authors: Christensen PM,Krustrup P,Gunnarsson TP,Kiilerich K,Nybo L,Bangsbo J

    更新日期:2011-09-01 00:00:00