Tissue and serum angiogenic activity is associated with low prevalence of ischemic complications in patients with giant-cell arteritis.

abstract：:To estimate the effect of distance between the electrode and the signal source on the amplitude of the His bundle electrogram (HBE) recorded during open heart surgery, a specially designed probe, containing six pairs of closely spaced (1 mm) electrodes was placed on the endocardial surface of the right atrium such tha...

journal_title：Circulation

authors： Dick M 2nd,Krongrad E,Antar RE,Ross S,Bowman FO Jr,Malm JR,Hoffman BF

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Factor Xa and factor IIa (thrombin) play roles in thrombotic complications after percutaneous coronary intervention. M118 is a novel low-molecular-weight heparin that has been rationally designed to capture the desired attributes of unfractionated heparin (UFH) and low-molecular-weight heparin: Potent activi...

journal_title：Circulation

authors： Rao SV,Melloni C,Myles-Dimauro S,Broderick S,Kosinski AS,Kleiman NS,Dzavík V,Tanguay JF,Chandna H,Gammon R,Rivera E,Alexander JH,Fier I,Roach J,Becker RC,EMINENCE Investigators.

更新日期：2010-04-20 00:00:00

abstract：BACKGROUND:Recent studies suggest that the oxygen-sensing pathway consisting of transcription factor hypoxia-inducible factor and prolyl hydroxylase domain proteins (PHDs) plays a critical role in glucose metabolism. However, the role of adipocyte PHD in the development of obesity has not been clarified. We examined wh...

journal_title：Circulation

authors： Matsuura H,Ichiki T,Inoue E,Nomura M,Miyazaki R,Hashimoto T,Ikeda J,Takayanagi R,Fong GH,Sunagawa K

更新日期：2013-05-28 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy has emerged as an important therapy for advanced systolic heart failure. Among available cardiac resynchronization therapy pacing modes that restore ventricular synchrony, it is uncertain whether simultaneous biventricular (BiV), sequential BiV, or left ventricular (LV) paci...

journal_title：Circulation

authors： Rao RK,Kumar UN,Schafer J,Viloria E,De Lurgio D,Foster E

更新日期：2007-04-24 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) and interleukin 1 (IL-1) are proximal inflammatory cytokines that stimulate expression of adhesion molecules and induce synthesis of other proinflammatory cytokines. In addition, TNF-alpha and IL-1 influence vascular smooth muscle cell migration and proliferation in vi...

journal_title：Circulation

authors： Rectenwald JE,Moldawer LL,Huber TS,Seeger JM,Ozaki CK

更新日期：2000-10-03 00:00:00

abstract：:Diagnosis of rejection after cardiac transplantation is currently made by right ventricular endomyocardial biopsy. To evaluate antimyosin imaging as a noninvasive means of detecting human cardiac rejection, the Fab fragment of murine monoclonal antimyosin antibodies was labeled with indium-111 and given intravenously ...

journal_title：Circulation

authors： Frist W,Yasuda T,Segall G,Khaw BA,Strauss HW,Gold H,Stinson E,Oyer P,Baldwin J,Billingham M

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Adrenomedullin (AM) is a vasodilating peptide involved in the regulation of circulatory homeostasis and in the pathophysiology of certain cardiovascular diseases. To determine the extent to which chronic AM overproduction affects circulatory physiology under normal and pathological conditions, we used a prep...

journal_title：Circulation

authors： Shindo T,Kurihara H,Maemura K,Kurihara Y,Kuwaki T,Izumida T,Minamino N,Ju KH,Morita H,Oh-hashi Y,Kumada M,Kangawa K,Nagai R,Yazaki Y

更新日期：2000-05-16 00:00:00

abstract：BACKGROUND:This study aimed to assess if clampless off-pump coronary artery bypass grafting (CABG) decreases risk-adjusted mortality, stroke rate, and morbidity in unselected patients in comparison to conventional CABG. METHODS AND RESULTS:Between July 2009 and November 2010, data of 1282 consecutive patients undergoi...

journal_title：Circulation

authors： Börgermann J,Hakim K,Renner A,Parsa A,Aboud A,Becker T,Masshoff M,Zittermann A,Gummert JF,Kuss O

更新日期：2012-09-11 00:00:00

abstract：:The frequencies of onset of myocardial infarction and sudden cardiac death are increased between 6 AM and 12 noon. Platelet aggregability, which may play a role in the cause of these disorders, has been observed to increase after the normal morning activities of awakening, arising, and ambulating. To determine which m...

journal_title：Circulation

authors： Brezinski DA,Tofler GH,Muller JE,Pohjola-Sintonen S,Willich SN,Schafer AI,Czeisler CA,Williams GH

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Extracorporeal membrane oxygenation (ECMO) is considered when respiratory failure (RF) persists despite increasing conventional mechanical ventilation (CMV). High-frequency jet ventilation (HFJV) can improve ventilation with comparable mean airway pressure (PAW) to that found on CMV. This study was undertake...

journal_title：Circulation

authors： Kocis KC,Meliones JN,Dekeon MK,Callow LB,Lupinetti FM,Bove EL

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Myocardial perfusion reflects the macro- and microvascular coronary circulation. Recent quantitation developments using cardiovascular magnetic resonance perfusion permit automated measurement clinically. We explored the prognostic significance of stress myocardial blood flow (MBF) and myocardial perfusion r...

journal_title：Circulation

authors： Knott KD,Seraphim A,Augusto JB,Xue H,Chacko L,Aung N,Petersen SE,Cooper JA,Manisty C,Bhuva AN,Kotecha T,Bourantas CV,Davies RH,Brown LAE,Plein S,Fontana M,Kellman P,Moon JC

更新日期：2020-04-21 00:00:00

abstract：:Intermittent aortic root infusion of a cold solution containing either potassium chloride (KCl) or diltiazem was performed in 32 dogs during a 2-hour aortic clamping. Half of the dogs in each group had a critical stenosis created on the circumflex artery before cardiopulmonary bypass. Global left ventricular (LV) func...

journal_title：Circulation

authors： Vouhé PR,Hélias J,Robert P,Grondin CM

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Patients surviving ventricular fibrillation (VF) or sustained ventricular tachycardia (VT) are at a high risk of death due to a recurrence of arrhythmia. The implantable cardioverter defibrillator (ICD) terminates VT or VF, but it is not known whether this device prolongs life in these patients compared with...

journal_title：Circulation

authors： Connolly SJ,Gent M,Roberts RS,Dorian P,Roy D,Sheldon RS,Mitchell LB,Green MS,Klein GJ,O'Brien B

更新日期：2000-03-21 00:00:00

abstract：BACKGROUND:Early results of sirolimus-eluting stent implantation showed a nearly complete abolition of neointimal hyperplasia. The question remains, however, whether the early promising results will still be evident at long-term follow-up. The objective of our study was to evaluate the efficiency of sirolimus-eluting s...

journal_title：Circulation

authors： Degertekin M,Serruys PW,Foley DP,Tanabe K,Regar E,Vos J,Smits PC,van der Giessen WJ,van den Brand M,de Feyter P,Popma JJ

更新日期：2002-09-24 00:00:00

abstract：BACKGROUND:The coexistence of atrial fibrillation (AF) and atrial flutter (AFL) is well recognized. AF precedes the onset of AFL in almost all instances. We evaluated the effect of 2 ablation strategies in patients with paroxysmal AF (PAF) and AFL. METHODS AND RESULTS:Ninety-eight patients with PAF/AFL were prospectiv...

journal_title：Circulation

authors： Moreira W,Timmermans C,Wellens HJ,Mizusawa Y,Philippens S,Perez D,Rodriguez LM

更新日期：2007-12-11 00:00:00

abstract：BACKGROUND:Premedication with clopidogrel has reduced thrombotic complications after percutaneous coronary revascularization procedures. However, because of the enhanced and irreversible platelet inhibition by clopidogrel, patients requiring surgical revascularization have a higher risk of bleeding complications and tr...

journal_title：Circulation

authors： Kapetanakis EI,Medlam DA,Petro KR,Haile E,Hill PC,Dullum MK,Bafi AS,Boyce SW,Corso PJ

更新日期：2006-04-04 00:00:00

abstract：BACKGROUND:In people with atrial fibrillation (AF), periods of sinus rhythm present an opportunity to detect prothrombotic atrial remodeling through measurement of P-wave indices (PWIs)-prolonged P-wave duration, abnormal P-wave axis, advanced interatrial block, and abnormal P-wave terminal force in lead V1. We hypothe...

journal_title：Circulation

authors： Maheshwari A,Norby FL,Roetker NS,Soliman EZ,Koene RJ,Rooney MR,O'Neal WT,Shah AM,Claggett BL,Solomon SD,Alonso A,Gottesman RF,Heckbert SR,Chen LY

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Bias in studies of preventive medications can occur when healthier patients are more likely to initiate and adhere to therapy than less healthy patients. We sought evidence of this bias by examining associations between statin exposure and various outcomes that should not be causally affected by statin expos...

journal_title：Circulation

authors： Dormuth CR,Patrick AR,Shrank WH,Wright JM,Glynn RJ,Sutherland J,Brookhart MA

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:Although early intravenous beta-blocker therapy during acute myocardial infarction (AMI) reduces the incidence of fatal arrhythmias in patients not treated with thrombolytic agents, its antiarrhythmic effect in thrombolysed patients remains controversial. We investigated prospectively the arrhythmia incidenc...

journal_title：Circulation

authors： Heidbüchel H,Tack J,Vanneste L,Ballet A,Ector H,Van de Werf F

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Continuous whole-body perfusion for > 3 hours with a cold asanguineous blood substitute, hypothermosol (HTS) solution, has been reported to preserve organ function. We used this solution in a survival animal model to evaluate its possible application in extending the safe duration of deep hypothermic circula...

journal_title：Circulation

authors： Miura T,Laussen P,Lidov HG,DuPlessis A,Shin'oka T,Jonas RA

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Inflammation and thrombosis coexist in several disorders. Although it is recognized that leukocytes may induce a procoagulant state at sites of inflammation, the critical molecular determinants of this process remain largely unknown. METHODS AND RESULTS:To examine mechanisms of inflammation-induced thrombos...

journal_title：Circulation

authors： Hirahashi J,Hishikawa K,Kaname S,Tsuboi N,Wang Y,Simon DI,Stavrakis G,Shimosawa T,Xiao L,Nagahama Y,Suzuki K,Fujita T,Mayadas TN

更新日期：2009-09-29 00:00:00

abstract：BACKGROUND:Depressive symptoms have been associated with increased risk of coronary artery disease and poor prognosis among patients with existing coronary artery disease, but whether depressive symptoms specifically influence atherosclerotic progression among such patients is uncertain. METHODS AND RESULTS:The Post-C...

journal_title：Circulation

authors： Wellenius GA,Mukamal KJ,Kulshreshtha A,Asonganyi S,Mittleman MA

更新日期：2008-05-06 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is a major risk factor for cardiovascular diseases (CVDs), the leading cause of mortality worldwide. Both heritable and lifestyle risk factors contribute to elevated BP levels. We aimed to investigate the extent to which lifestyle factors could offset the effect of an adverse BP gene...

journal_title：Circulation

authors： Pazoki R,Dehghan A,Evangelou E,Warren H,Gao H,Caulfield M,Elliott P,Tzoulaki I

更新日期：2018-02-13 00:00:00

abstract：:The rapid development of new drugs, therapies, and devices has created a dramatic increase in the number of trials needed to properly evaluate them. The majority of patients treated today, many of whom could be eligible for participation in these studies, are seen in community hospitals and medical practices that are ...

journal_title：Circulation

authors： Lader EW,Cannon CP,Ohman EM,Newby LK,Sulmasy DP,Barst RJ,Fair JM,Flather M,Freedman JE,Frye RL,Hand MM,Jesse RL,Van de Werf F,Costa F,American College of Cardiology Foundation.

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Long-term ventricular resynchronization therapy improves symptom status. Changes in left ventricular remodeling have not been adequately evaluated. METHODS AND RESULTS:Fifty-three patients with systolic heart failure and bundle-branch block underwent implantation of biventricular stimulation (BVS) devices a...

journal_title：Circulation

authors： Saxon LA,De Marco T,Schafer J,Chatterjee K,Kumar UN,Foster E,VIGOR Congestive Heart Failure Investigators.

更新日期：2002-03-19 00:00:00

abstract：BACKGROUND:31P metabolite measurements in the human heart by magnetic resonance spectroscopy (MRS) have been reported previously. By use of a method in which metabolite content was quantified with reference to a standard located outside the chest, it has become possible to measure the content of phosphocreatine (PCr) a...

journal_title：Circulation

authors： Yabe T,Mitsunami K,Inubushi T,Kinoshita M

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Imaging of the flow convergence region (FCR) proximal to a regurgitant orifice has been shown to provide a method for quantifying the regurgitant flow rate. According to the continuity principle, the FCR is constituted by concentric hemispheric isovelocity surfaces centered at the orifice. The flow rate is c...

journal_title：Circulation

authors： Bargiggia GS,Tronconi L,Sahn DJ,Recusani F,Raisaro A,De Servi S,Valdes-Cruz LM,Montemartini C

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome caused by heparin. Complications range from thrombocytopenia to thrombocytopenia with thrombosis. We report a prospective, historical- controlled study evaluating the efficacy and safety of argatroban, a direct thrombin inhibitor, as antic...

journal_title：Circulation

authors： Lewis BE,Wallis DE,Berkowitz SD,Matthai WH,Fareed J,Walenga JM,Bartholomew J,Sham R,Lerner RG,Zeigler ZR,Rustagi PK,Jang IK,Rifkin SD,Moran J,Hursting MJ,Kelton JG,ARG-911 Study Investigators.

更新日期：2001-04-10 00:00:00

abstract：:This study examined quantitative regional myocardial perfusion (RMP) measured by the washout of 133Xe at rest and after an isoproterenol challenge in 50 patients (group I) studied 8 to 14 days after they underwent saphenous vein bypass grafting to the left coronary artery, and compared this with RMP measured in the na...

journal_title：Circulation

authors： Schmidt DH,Blau FM,Hendrix LJ,Kamath ML,Ray G

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:We have previously suggested that the primary arterial switch operation is a feasible strategy for patients with transposition of the great arteries and intact ventricular septum (TGA-IVS) up to age 2 months. This study reports our current results with this approach and examines whether this policy could be ...

journal_title：Circulation

authors： Kang N,de Leval MR,Elliott M,Tsang V,Kocyildirim E,Sehic I,Foran J,Sullivan I

更新日期：2004-09-14 00:00:00