Renal allograft loss due to proximal extension of ileofemoral deep venous thrombosis.

Abstract:

:Renal allograft recipients with thrombophilic (hypercoagulable) states are at higher risk for early allograft loss. Presumably, the combination of endothelial injury at surgery and thrombophilia predisposes to arterial or venous thrombosis. Of 270 consecutive renal transplants at our center one allograft failed secondary to renovascular thrombosis. At exploration the iliac and renal veins were thrombosed. Thrombectomy and re-implantation were attempted, but unsuccessful. Also noted at surgery was extensive clot in the femoral vein that could not be removed by embolectomy catheters. Post-operatively, a Doppler ultrasound confirmed the presence of extensive deep venous thrombosis (DVT) in the femoral and popliteal veins. The adherent nature of this clot, the extent of clot found less than 12 h after renal transplantation and the absence of leg edema suggested that the DVT existed prior to surgery. This case demonstrates that a pre-existing, asymptomatic DVT can precipitate allograft thrombosis and highlights the importance of diagnosing thrombophilia in patients undergoing renal transplantation. Current practices in our unit have evolved to include screening for thrombophilia in all patients with a suggestive history. As thrombophilic states are increasingly appreciated in the end-stage renal disease population, effective management of these patients while on hemodialysis and at the time of renal transplantation presents an ongoing challenge.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Ramirez PJ,Gohh RY,Kestin A,Monaco AP,Morrissey PE

doi

10.1034/j.1399-0012.2002.02006.x

subject

Has Abstract

pub_date

2002-08-01 00:00:00

pages

310-3

issue

4

eissn

0902-0063

issn

1399-0012

pii

2c006

journal_volume

16

pub_type

杂志文章
  • Weight gain after kidney donation: Association with increased risks of type 2 diabetes and hypertension.

    abstract::In the general population, obesity is associated with an increased risk of developing hypertension (HTN), type 2 diabetes mellitus (DM), and end-stage renal disease (ESRD). Therefore, most transplant centers have a body mass index (BMI) threshold for accepting living kidney donors. But there have been no studies of po...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13360

    authors: Issa N,Sánchez OA,Kukla A,Riad SM,Berglund DM,Ibrahim HN,Matas AJ

    更新日期:2018-09-01 00:00:00

  • Prognostic role of pre-transplantation serum C-reactive protein levels in patients with acute leukemia undergoing myeloablative allogeneic stem cell transplantation.

    abstract::The aim of this study was to identify indicators of outcome prior to transplantation in allogeneic hematopoietic stem cell transplantation (HCT). Clinical data of 106 patients with acute leukemia were retrospectively analyzed. We examined the role of pre-conditioning serum C-reactive protein (CRP) and ferritin levels,...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12028

    authors: Akı ŞZ,Suyanı E,Bildacı Y,Çakar MK,Baysal NA,Sucak GT

    更新日期:2012-09-01 00:00:00

  • Ethnicity, medical insurance, and living kidney donation.

    abstract:BACKGROUND:Relationships between race/ethnicity, recipient medical insurance, and living donor kidney transplantation (LKT) are incompletely described. METHODS:Associations between medical insurance and LKT were assessed in 447 recipients at a southeastern US transplant center. Primary and secondary payers were includ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12168

    authors: Reeves-Daniel AM,Farney AC,Fletcher AJ,Assimos D,Westcott C,Rogers J,Stratta RJ,Rocco MV,Freedman BI

    更新日期:2013-07-01 00:00:00

  • Prospective study of microchimerism in renal allograft recipients: association between HLA-DR matching, microchimerism and acute rejection.

    abstract::The presence of donor-derived hematopoietic cells in blood and various tissues of the organ recipients, termed allogeneic microchimerism, has been considered to play an essential role in establishment of organ acceptance. In this study, we prospectively determined the presence of peripheral blood microchimerism (PBM) ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2001.150308.x

    authors: Tajik N,Singal D,Pourmand G,Ebrahimi-Rad M,Radjabzadeh M,Tavasoli P,Khosravi F,Nikbin B

    更新日期:2001-06-01 00:00:00

  • Caring for the pregnant kidney transplant recipient.

    abstract::As fertility can be restored to normal soon after a kidney transplant, it is important for physicians caring for recipients to be able to inform the patient about the potential risks of pregnancy. Current opinion is that pregnancy can be successful if carried out under optimal circumstances, including stable allograft...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2011.01492.x

    authors: Concepcion BP,Schaefer HM

    更新日期:2011-11-01 00:00:00

  • A call to action: Feasible strategies to reduce the discard of transplantable kidneys in the United States.

    abstract::Changes to the United States kidney allocation system targeted at reducing organ discard have failed to improve organ utilization. High Kidney Donor Profile Index kidneys continue to be discarded at high rates as a result of the regulatory and financial barriers to widespread utilization of these organs. However, ther...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13990

    authors: Stewart ZA,Shah SA,Formica RN,Kandaswamy R,Paramesh AS,Friedman J,Squires R,Cooper M,Axelrod DA

    更新日期:2020-09-01 00:00:00

  • Efficacy of tonsillectomy for patients with recurrence of IgA nephropathy after kidney transplantation.

    abstract::From January 2007, we started to perform the tonsillectomy for every patient with recurrent IgA nephropathy (IgAN) after kidney transplantation. Up to September 2008, four recipients with primary IgAN had biopsy-proven recurrent IgAN. They had also progressive hematuria or proteinuria from on the average 14.3 months a...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2009.01003.x

    authors: Ushigome H,Suzuki T,Fujiki M,Nobori S,Sakamoto S,Okamoto M,Urasaki K,Yoshimura N

    更新日期:2009-08-01 00:00:00

  • Brain natriuretic peptide and right heart dysfunction after heart transplantation.

    abstract::Heart transplantation (HT) should normalize cardiac endocrine function, but brain natriuretic peptide (BNP) levels remain elevated after HT, even in the absence of left ventricular hemodynamic disturbance or allograft rejection. Right ventricle (RV) abnormalities are common in HT recipients (HTx), as a result of engra...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/ctr.12969

    authors: Talha S,Charloux A,Piquard F,Geny B

    更新日期:2017-06-01 00:00:00

  • Development of the living donation and kidney transplantation information made easy (KidneyTIME) educational animations.

    abstract:BACKGROUND:Current web-based educational approaches about living kidney donation (LKD) are complex, lengthy, and/or text-laden, which may impair accurate interpretation of information, thereby limiting kidney transplant access. PURPOSE:This paper describes the process of developing animation-based LKD education design...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13830

    authors: Kayler LK,Dolph B,Seibert R,Keller M,Cadzow R,Feeley TH

    更新日期:2020-04-01 00:00:00

  • Orthotopic liver transplantation for adults with Alagille syndrome.

    abstract:INTRODUCTION:Alagille syndrome (AGS) is an inherited multisystem disorder, and liver transplantation (LT) may be required in pediatric patients with AGS (P-AGS). There are limited data regarding the outcomes of LT in adults with AGS (A-AGS). AIM:To determine and compare the outcomes of LT in A-AGS vs. P-AGS as well as...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2011.01574.x

    authors: Arnon R,Annunziato R,Schiano T,Miloh T,Baisley M,Sogawa H,Contreras AG,Lee S,Kerkar N

    更新日期:2012-03-01 00:00:00

  • Post-transplantation diabetes mellitus: evaluation of treatment strategies.

    abstract:BACKGROUND:Post-transplantation diabetes mellitus (PTDM) is a serious complication after kidney transplantation, but evidence regarding long-term outcomes of treatment regimens remains scarce. AIM AND METHODS:The aim of this retrospective cohort analysis was to assess the long-term efficiency and safety of antidiabeti...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12541

    authors: Haidinger M,Antlanger M,Kopecky C,Kovarik JJ,Säemann MD,Werzowa J

    更新日期:2015-05-01 00:00:00

  • Clinical outcomes of liver transplantation for HBV-related hepatocellular carcinoma: data from the NIH HBV OLT study.

    abstract:BACKGROUND:Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is an indication for orthotopic liver transplantation (OLT) in patients with tumor stage within the United Network for Organ Sharing criteria. The number of patients listed for HBV-related HCC is increasing, while the number of patients listed fo...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2010.01349.x

    authors: Han SH,Reddy KR,Keeffe EB,Soldevila-Pico C,Gish R,Chung RT,Degertekin B,Lok A,NIH HBV OLT Study Group.

    更新日期:2011-03-01 00:00:00

  • The Transplant Palliative Care Clinic: An early palliative care model for patients in a transplant program.

    abstract::Although patients within a transplant program are awaiting or have received disease modifying or curative treatment, they are also facing advanced illness and the possibility of death. The involvement of specialized palliative care services for these patients may improve symptom management and facilitate advance care ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12838

    authors: Wentlandt K,Dall'Osto A,Freeman N,Le LW,Kaya E,Ross H,Singer LG,Abbey S,Clarke H,Zimmermann C

    更新日期:2016-12-01 00:00:00

  • Urinary microbiome associated with chronic allograft dysfunction in kidney transplant recipients.

    abstract:BACKGROUND:We performed a study to identify differences in the urinary microbiome associated with chronic allograft dysfunction (CAD) and compared the urinary microbiome of male and female transplant recipients with CAD. METHODS:This case-control study enrolled 67 patients within the Deterioration of Kidney Allograft ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13436

    authors: Wu JF,Muthusamy A,Al-Ghalith GA,Knights D,Guo B,Wu B,Remmel RP,Schladt DP,Alegre ML,Oetting WS,Jacobson PA,Israni AK

    更新日期:2018-12-01 00:00:00

  • Differential gene expression in non-adherent heart transplant survivors: Implications for regulatory T-cell expression.

    abstract::Survival despite prolonged non-adherence with immunosuppression is rare but has been reported in kidney, lung, and liver transplantation. Its occurrence in heart transplantation is quite rare. Our study was prompted by an index patient who survived despite prolonged medication non-adherence. Prospective consent and bl...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13834

    authors: Baran DA,Rao P,Deo D,Zucker MJ

    更新日期:2020-05-01 00:00:00

  • Liver transplantation in patients aged 65 and over: a case-control study.

    abstract:INTRODUCTION:The average age of patients undergoing liver transplantation (LT) is consistently increasing. The aim of this case-control study is to evaluate survival and outcome of patients ≥65 yr compared to younger patients undergoing LT. MATERIALS AND METHODS:From 10/00 to 4/08 we performed 330 primary LT, 31 (9.4%...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2010.01230.x

    authors: Montalti R,Rompianesi G,Di Benedetto F,Ballarin R,Gerring RC,Busani S,De Pietri L,De Ruvo N,Iemmolo RM,Guerrini GP,Smerieri N,Gerunda GE

    更新日期:2010-09-01 00:00:00

  • Correlation between myocardial fibrosis and restrictive cardiac physiology in patients undergoing retransplantation.

    abstract::After cardiac transplant, there is often development of restrictive cardiac physiology. Little is known about the factors that contribute to this physiology and its correlation with pathology. Heart retransplantation provides a valuable opportunity to further understand this relationship. In this study, we investigate...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/ctr.12250

    authors: Kobashigawa JA,Itagaki BK,Razi RR,Patel JK,Chai W,Kawano MA,Goldstein Z,Kittleson MM,Fishbein MC

    更新日期:2013-11-01 00:00:00

  • Mycobacterium tuberculosis after solid organ transplantation: A review of more than 2000 cases.

    abstract:BACKGROUND:Mycobacterium tuberculosis (TB) is a common pathogen worldwide, and it may cause significant infection after solid organ transplantation (SOT). We reviewed all reported TB cases to provide an update on its epidemiology, clinical presentation, management, and outcome after SOT. METHODS:MEDLINE, EMBASE, and O...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/ctr.13259

    authors: Abad CLR,Razonable RR

    更新日期:2018-06-01 00:00:00

  • Calcification score evaluation in patients listed for renal transplantation.

    abstract::Based on native CT scans of the pelvic region using a standardized calcification score, evaluation of iliac vascular calcification was performed between 2008 and 2012 prior to listing for renal transplantation in 205 patients with chronic kidney disease. Vascular calcification showed a decrease from proximal to distal...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12888

    authors: Kahn J,Ram LM,Eberhard K,Groselj-Strele A,Obermayer-Pietsch B,Müller H

    更新日期:2017-03-01 00:00:00

  • Long-term clinicopathological impact of calcineurin inhibitor cessation without specific cytoreductive induction in kidney transplantation.

    abstract::Calcineurin inhibitors (CNIs) have considerably improved renal allograft survival. However, their chronic use has various adverse effects, including hypertension, hyperlipidemia, and nephrotoxicity. We conducted a retrospective study of kidney transplant recipients using a CNI withdrawal protocol. Eleven of 13 patient...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12274

    authors: Tanabe T,Morita K,Fujita H,Hatanaka K,Ogawa Y,Hirose T,Sasaki H,Iwami D,Hotta K,Nonomura K

    更新日期:2013-11-01 00:00:00

  • Attitude toward xenotransplantation of patients prior and after human organ transplantation.

    abstract::Xenotransplantation is a potential strategy to overcome the shortage of human donor organs. As this technique has a major medical and psychological impact on patients and their family and friends, the attitude of patients currently waiting for organ transplantation is important. Therefore, we conducted a survey on the...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2010.01296.x

    authors: Stadlbauer V,Stiegler P,Müller S,Schweiger M,Sereingg M,Tscheliessnigg KH,Freidl W

    更新日期:2011-05-01 00:00:00

  • Regulatory T cells and tolerance induction.

    abstract::Transplantation tolerance is the ultimate goal of organ transplantation. Natural regulatory T cells (Treg) have been expected to reach clinical applications for tolerance induction because their initial description. More than ten yr later, Treg have started moving from experimental animal models into clinical applicat...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2009.01103.x

    authors: Fritzsching E,Kunz P,Maurer B,Pöschl J,Fritzsching B

    更新日期:2009-12-01 00:00:00

  • The association of acute rejection vs recurrent glomerular disease with graft outcomes after kidney transplantation.

    abstract:BACKGROUND:It has been shown that glomerulonephritis (GN) recurrence affects graft survival more than acute rejection. Thus, we assessed allograft survival after biopsy-confirmed diagnosis of acute rejection or recurrent GN in current era of immunosuppression. METHODS:Allograft survival following a biopsy diagnosis of...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13738

    authors: Singh T,Astor BC,Zhong W,Mandelbrot DA,Maursetter L,Panzer SE

    更新日期:2019-12-01 00:00:00

  • Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection.

    abstract::To assess the prevalence and long-term impact of HCV on kidney transplant recipients, we assayed 716 pre-transplant sera using a first-generation ELISA. The anti-HCV positive sera were confirmed by a 6-antigen radioimmunoassay (RIA). Patients were followed up for 5 years. Graft survival, function, evidence of chemical...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Orloff SL,Stempel CA,Wright TL,Tomlanovich SJ,Amend WJ,Stock PG,Melzer JS,Vincenti F

    更新日期:1995-04-01 00:00:00

  • Effect of storage temperature on early graft function following liver transplantation.

    abstract::The effect of storage temperature on early graft function following liver transplantation was investigated by analyzing the results following transplantation during three periods in which different techniques for graft storage were used. The techniques involved ice-packing (period 1), storage in a standard operating ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Morino M,Adam R,Diamond T,Castaing D,Reynes M,Bismuth H

    更新日期:1992-04-01 00:00:00

  • CXCL10 levels identify individuals with rapid fibrosis at 12 months post-transplant for hepatitis C virus and predict treatment response.

    abstract:BACKGROUNDS:Recurrent hepatitis C virus (HCV) infection is universal post-transplantation. Fibrosis (F) stage ≥2 at 12 months identifies patients with rapid fibrosis progression. Antiviral therapy (AVT) remains the only option to attenuate fibrosis progression. We hypothesized that CXCL10 levels can distinguish between...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12354

    authors: Joshi D,Carey I,Foxton M,Al-Freah M,Bruce M,Heaton N,Quaglia A,O'Grady J,Aluvihare V,Agarwal K

    更新日期:2014-05-01 00:00:00

  • Influence of dialysis on post-transplant events.

    abstract:INTRODUCTION:We examined the effect of haemodialysis (HD) or peritoneal dialysis (PD) on acute rejection, delayed graft function (DGF), graft and patient survival after cadaveric renal transplantation. MATERIALS AND METHODS:We carried out a retrospective analysis of 325 patients (cyclosporin [CyA]-based therapy) who h...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2002.00069.x

    authors: Joseph JT,Jindal RM

    更新日期:2002-02-01 00:00:00

  • Diagnosis of kidney transplant obstruction using Mag3 diuretic renography.

    abstract::Kidney transplant obstruction (KTO) following renal transplantation remains an important reversible cause of allograft dysfunction, requiring prompt diagnosis to prevent long-term graft damage. Although ultrasound can accurately diagnose renal transplant hydronephrosis, it cannot be used to assess its functional signi...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2001.150103.x

    authors: Nankivell BJ,Cohn DA,Spicer ST,Evans SG,Chapman JR,Gruenewald SM

    更新日期:2001-02-01 00:00:00

  • Heparin infusion in simultaneous pancreas and kidney transplantation reduces graft thrombosis and improves graft survival.

    abstract:INTRODUCTION:Thrombosis of the pancreas after transplantation is the most common cause of relaparotomy and resultant graft loss. There is currently no standard protocol consistently proven to prevent thrombosis following transplantation. Our objective was to determine whether our protocol of post-operative low-dose int...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12780

    authors: Aboalsamh G,Anderson P,Al-Abbassi A,McAlister V,Luke PP,Sener A

    更新日期:2016-09-01 00:00:00

  • Heart transplantation in the early phase of the COVID-19 pandemic: A single-center case series.

    abstract::The infectious disease coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization in March 2020. The impact of COVID-19 on solid organ transplantations, including heart transplantation, is currently unclear. Many transplant programs have been forced to swiftly re-evaluate and adapt th...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14042

    authors: Hsu JJ,Al-Saffar F,Ardehali R,Baas AS,Carlson M,Cruz D,Deng M,Fan A,Fraschilla S,Gaynor P,Kamath M,Kubak BM,Schaenman J,Stimpson E,Vucicevic D,Ardehali A,Nsair A

    更新日期:2020-09-01 00:00:00