Importance of sympathetic activation for the expression of Na+-Ca2+ exchanger in end-stage failing human myocardium.

abstract：:Recently published epidemiological and genetic studies strongly suggest a causal relationship of elevated concentrations of lipoprotein (a) [Lp(a)] with cardiovascular disease (CVD), independent of low-density lipoproteins (LDLs), reduced high density lipoproteins (HDL), and other traditional CVD risk factors. The ath...

journal_title：European heart journal

authors： Kostner KM,März W,Kostner GM

更新日期：2013-11-01 00:00:00

abstract：Aims:Optimal blood pressure for prevention of cardiovascular (CV) events in patients with Type 2 diabetes mellitus (T2DM) remains uncertain and there is concern for increased risk with low diastolic blood pressure (DBP). This study analysed the association between blood pressure and CV outcomes in high-risk patients wi...

journal_title：European heart journal

authors： Bergmark BA,Scirica BM,Steg PG,Fanola CL,Gurmu Y,Mosenzon O,Cahn A,Raz I,Bhatt DL,SAVOR-TIMI 53 Investigators.

更新日期：2018-06-21 00:00:00

abstract：AIMS:Early and late microvascular obstruction (MO) assessed by magnetic resonance imaging (MRI) are prognostic markers for combined clinical endpoints after ST-elevation myocardial infarction (STEMI). However, there are only limited data for hard endpoints and no consensus exists which of the two best predicts clinical...

journal_title：European heart journal

authors： de Waha S,Desch S,Eitel I,Fuernau G,Zachrau J,Leuschner A,Gutberlet M,Schuler G,Thiele H

更新日期：2010-11-01 00:00:00

abstract：:Thrombolytic treatment efficacy is greater when the delay between onset of pain and treatment is short. One way to shorten this delay is to give treatment at home, but one cannot recommend this technique if it has not been demonstrated first, that pre-hospital thrombolysis is feasible and safe, and second, that it is ...

journal_title：European heart journal

authors： Castaigne AD,Hervé C,Duval-Moulin AM,Gaillard M,Dubois-Randé JL,Lellouche D

更新日期：1990-08-01 00:00:00

abstract：AIMS:The utilization and timing of revascularization in unstable coronary artery disease varies, which could have important consequences for patients and for treatment costs. The FRISC II invasive trial compared an early invasive strategy vs a non-invasive strategy with respect to the composite end-point of death and m...

journal_title：European heart journal

authors： Janzon M,Levin LA,Swahn E

更新日期：2002-01-01 00:00:00

abstract：AIMS:Coronary artery dissections are common findings following percutaneous transluminal coronary angioplasty and occur with an incidence of approximately 20% to 40%. The purpose of this study was to evaluate the impact of intravascular ultrasound for the prediction of severe dissections by pre-interventional analysis ...

journal_title：European heart journal

authors： Athanasiadis A,Haase KK,Wullen B,Treusch AW,Mahrholdt H,Voelker W,Baumbach A,Oberhoff M,Karsch KR

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:In patients with postinfarction sustained ventricular tachycardia showing one or more antiarrhythmic drug failures, the question is how long to proceed with new drug trials before deciding to perform map-guided arrhythmia surgery. Although the techniques of this surgery developed rapidly in the early 1980s, ...

journal_title：European heart journal

authors： van Hemel NM,Kingma JH,Defauw JJ,Hoogteijling-van Dusseldorp E,Kelder JC,Beukema WP,Vermeulen FE

更新日期：1996-04-01 00:00:00

abstract：:Early treatment with ACE inhibitors of even moderate heart failure is clinically beneficial, even though haemodynamic measurements cannot adequately quantitate such improvement. Neurohumoral assessment is, however, supposed to be more accurate. In 55 patients with moderate heart failure (ejection fraction < or = 35%),...

journal_title：European heart journal

authors： Nussberger J,Fleck E,Bahrmann H,Delius W,Schultheiss HP,Brunner HR

更新日期：1994-12-01 00:00:00

abstract：AIMS:Homozygous familial hypercholesterolaemia (HoFH) is a rare life-threatening condition characterized by markedly elevated circulating levels of low-density lipoprotein cholesterol (LDL-C) and accelerated, premature atherosclerotic cardiovascular disease (ACVD). Given recent insights into the heterogeneity of geneti...

journal_title：European heart journal

authors： Cuchel M,Bruckert E,Ginsberg HN,Raal FJ,Santos RD,Hegele RA,Kuivenhoven JA,Nordestgaard BG,Descamps OS,Steinhagen-Thiessen E,Tybjærg-Hansen A,Watts GF,Averna M,Boileau C,Borén J,Catapano AL,Defesche JC,Hovingh GK,Hump

更新日期：2014-08-21 00:00:00

abstract：AIMS:To assess the outcome and costs of patients with acute myocardial infarction (AMI) after initial admission to hospitals with or without catheterization facilities in Belgium. METHODS AND RESULTS:From a nationwide hospital register, we retrieved the data of 34 961 patients discharged during 1999-2001 with a princi...

journal_title：European heart journal

authors： Van Brabandt H,Camberlin C,Vrijens F,Parmentier Y,Ramaekers D,Bonneux L

更新日期：2006-11-01 00:00:00

abstract：AIMS:Delayed lipoprotein clearance is associated with atherosclerosis. This study examined whether chronic intermittent hypoxia (CIH), a hallmark of obstructive sleep apnoea (OSA), can lead to hyperlipidaemia by inhibiting clearance of triglyceride rich lipoproteins (TRLP). METHODS AND RESULTS:Male C57BL/6J mice on hi...

journal_title：European heart journal

authors： Drager LF,Li J,Shin MK,Reinke C,Aggarwal NR,Jun JC,Bevans-Fonti S,Sztalryd C,O'Byrne SM,Kroupa O,Olivecrona G,Blaner WS,Polotsky VY

更新日期：2012-03-01 00:00:00

abstract：:To assess possible clinical and angiographic factors associated with acute coronary events following PTCA, we performed quantitative angiography in 168 consecutive patients who had undergone successful angioplasty in a native vessel (94 for stable angina, 74 for unstable angina), and who were restudied (24 +/- 15 week...

journal_title：European heart journal

authors： Chen L,Leatham E,Chester M,Huang J,Kaski JC

更新日期：1995-08-01 00:00:00

abstract：AIMS:The risk of gastrointestinal (GI) bleeding limits the use of antiplatelet and anticoagulant drugs. Risk factors for GI bleeding in post- myocardial infarction (MI) patients have not been well defined. We sought to identify risk factors for GI bleeding in patients following MI. METHODS AND RESULTS:The VALsartan In...

journal_title：European heart journal

authors： Moukarbel GV,Signorovitch JE,Pfeffer MA,McMurray JJ,White HD,Maggioni AP,Velazquez EJ,Califf RM,Scheiman JM,Solomon SD

更新日期：2009-09-01 00:00:00

abstract：AIMS:Adverse left ventricular (LV) remodelling after myocardial infarction (MI) frequently leads to congestive heart failure (CHF). We have previously shown that myocardial beta-adrenoceptor density (beta-ARD) is reduced soon after acute MI and correlates with LV dilatation in the short term. The aim of the present stu...

journal_title：European heart journal

authors： Gaemperli O,Liga R,Spyrou N,Rosen SD,Foale R,Kooner JS,Rimoldi OE,Camici PG

更新日期：2010-07-01 00:00:00

abstract：:The effects of oral sotalol were compared with the findings obtained in the baseline study of a group of 26 consecutive patients with sustained monomorphic ventricular tachycardia or ventricular fibrillation and inducible ventricular tachycardia. The mean age was 62 years and the mean ejection fraction 33%. The number...

journal_title：European heart journal

authors： Jordaens LJ,Palmer A,Clement DL

更新日期：1989-03-01 00:00:00

abstract：AIMS:Although inflammation contributes to cardiovascular disease, the associations of appendectomy and tonsillectomy, which remove mucosa-associated lymphoid tissue, with risk of acute myocardial infarction (AMI) are unknown. Our aim was to assess the association between these operations performed in childhood and AMI ...

journal_title：European heart journal

authors： Janszky I,Mukamal KJ,Dalman C,Hammar N,Ahnve S

更新日期：2011-09-01 00:00:00

abstract：AIMS:Our objectives were (i) to compare the discriminatory performance of the Thrombolysis in Myocardial Infarction risk score (TIMI RS), Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy risk score (PURSUIT RS), and Global Registry of Acute Cardiac Events risk score (GRAC...

journal_title：European heart journal

authors： Yan AT,Yan RT,Tan M,Casanova A,Labinaz M,Sridhar K,Fitchett DH,Langer A,Goodman SG

更新日期：2007-05-01 00:00:00

abstract：AIMS:The aim of the study was to compare the 10-year follow-up results of patients with or without restenosis following single-vessel percutaneous transluminal coronary angioplasty (PTCA). METHODS AND RESULTS:A total of 313 patients with successful PTCA (> or = 20% reduction in luminal diameter narrowing without acute...

journal_title：European heart journal

authors： Espinola-Klein C,Rupprecht HJ,Erbel R,Nafe B,Brennecke R,Meyer J

更新日期：1998-07-01 00:00:00

abstract：AIMS:Long-term randomized comparisons of percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) in left main coronary (LM) disease and/or three-vessel disease (3VD) patients have been limited. This analysis compares 3-year outcomes in LM and/or 3VD patients treated with CABG or PCI with TAXU...

journal_title：European heart journal

authors： Kappetein AP,Feldman TE,Mack MJ,Morice MC,Holmes DR,Ståhle E,Dawkins KD,Mohr FW,Serruys PW,Colombo A

更新日期：2011-09-01 00:00:00

abstract：AIMS:A lack of donor hearts has stimulated interest in using blood pumps to treat severe heart failure. We tested the hypothesis that a new continuous flow circulatory assist device could be employed safely to relieve symptoms of heart failure and evaluated the potential to prolong life. METHODS AND RESULTS:An intraca...

journal_title：European heart journal

authors： Siegenthaler MP,Westaby S,Frazier OH,Martin J,Banning A,Robson D,Pepper J,Poole-Wilson P,Beyersdorf F

更新日期：2005-05-01 00:00:00

abstract：:Contraceptive counselling should begin early in females with heart disease, preferably directly after the start of menstruation. In coming to a decision about the method of contraception, the following issues should be considered: (i) the risk of pregnancy for the mother and the consequences of an unplanned pregnancy;...

journal_title：European heart journal

authors： Roos-Hesselink JW,Cornette J,Sliwa K,Pieper PG,Veldtman GR,Johnson MR

更新日期：2015-07-14 00:00:00

abstract：:Treatment of 8 hypertensive elderly subjects with atenolol or with labetalol did not affect exercise performance, except after the development of circulatory congestion in 1 patient. Treatment with beta blockers did not alter the response to an exercise training programme in 15 elderly patients with ischaemic heart di...

journal_title：European heart journal

authors： Fagard R,Reybrouck T,Vanhees L,Cattaert A,Vanmeenen T,Grauwels R,Amery A

更新日期：1984-11-01 00:00:00

abstract：:In this study, the acute haemodynamic effects of angiotensin converting enzyme (ACE) inhibition with intravenous enalaprilat alone or in combination with preload restoration were determined in patients with severe heart failure complicating acute myocardial infarction. Ten patients with raised pulmonary arterial wedge...

journal_title：European heart journal

authors： Tohmo H,Karanko M,Korpilahti K

更新日期：1994-04-01 00:00:00

abstract：:The long-term efficacy of transdermal nitrate therapy, in particular the ability of a single patch to provide 24 h prophylaxis against angina, has been questioned. Two mechanisms have been suggested for this loss of effect: the development of pharmacological tolerance, and premature patch exhaustion. This study was de...

journal_title：European heart journal

authors： James MA,Papouchado M,Jones JV

更新日期：1991-12-01 00:00:00

abstract：:Hypertension induced in rats by suprarenal banding has a blood pressure elevating effect that is accompanied by the occurrence of cardiac hypertrophy and fibrosis. This phenomenon is already present at 2 weeks after banding and persists up to 1.5 years. The increase in cardiac weight is mostly due to the development o...

journal_title：European heart journal

authors： Nagasawa K,Zimmermann R,Münkel B,Linz W,Schölkens B,Schaper J

更新日期：1995-05-01 00:00:00

abstract：AIMS:The objectives of this study were to determine the association of waist circumference (WC) and waist-to-hip ratio (WHR) with the risk of incident cardiovascular disease (CVD) events and to determine whether the strength of association of WC and WHR with CVD risk is different. METHODS AND RESULTS:This meta-regress...

journal_title：European heart journal

authors： de Koning L,Merchant AT,Pogue J,Anand SS

更新日期：2007-04-01 00:00:00

abstract：:Ventricular arrhythmias present with strongly varying intensity. This spontaneous variability makes it difficult to use one of the existing arrhythmia grading systems for risk or therapy efficacy studies. We attempted to explain the variability by the changing autonomic, ischaemic, circadian, and rhythmic factors. Fou...

journal_title：European heart journal

authors： Janssen MJ,Swenne CA,Manger Cats V,van Bemmel JH,Bruschke AV

更新日期：1995-05-01 00:00:00

abstract：:Opiate agonists were administered into the cisterna magna of normotensive urethane-anaesthetized artificially-ventilated rats. Increases in blood pressure and heart rate were produced by fentanyl (0.3-3.0 nmol). [D-ala]2-met-enkephalinamide (17 nmol), and beta-endorphin (2.9 nmol). On the contrary, ethylketocyclazocin...

journal_title：European heart journal

authors： Laurent S,Schmitt H

更新日期：1983-11-01 00:00:00

abstract：AIMS:To document the impact of intensive insulin therapy during intensive care on long-term (4 years) outcome of high-risk cardiac surgery patients. METHODS AND RESULTS:In this pre-planned sub-analysis and follow-up study of a large, randomized controlled trial on the effects of intensive insulin therapy during critic...

journal_title：European heart journal

authors： Ingels C,Debaveye Y,Milants I,Buelens E,Peeraer A,Devriendt Y,Vanhoutte T,Van Damme A,Schetz M,Wouters PJ,Van den Berghe G

更新日期：2006-11-01 00:00:00

abstract：Aims:Vascular ageing is characterized by arterial stiffening, dilation, and arterial wall thickening. We investigated the extent to which these changes are related and their heritability during 5 year follow-up in the Twins UK cohort. Methods and results:Carotid-femoral pulse wave velocity (PWVcf), carotid diameter, c...

journal_title：European heart journal

authors： Cecelja M,Jiang B,Keehn L,Hussain T,Silva Vieira M,Phinikaridou A,Greil G,Spector TD,Chowienczyk P

更新日期：2018-06-21 00:00:00