Abstract:
INTRODUCTION:Neurotoxoplasmosis (NTX) is one of the commonest opportunist infections in patients infected by the human immunodeficiency virus. It presents with a variety of clinical features in the immunocompromised patient. PATIENTS AND METHODS:We made a horizontal retrospective descriptive study of 88 patients with a diagnosis of NTX treated in the Pedro Kour Institute during a three years period. Our aim was to find which were the most common forms of clinical presentation in our setting and to evaluate the use of paraclinical examinations in reaching the presumptive diagnosis. The patients had clinical examinations, CSF studies, detection of indirect immunofluorescence titres (IFI) for Toxoplasma, imaging studies (CAT) and lymphocyte counts. RESULTS:The commonest symptoms were: headache in 79%, fever in 55.68%, motor defect in 44.31% and disorders of consciousness in 29.54% of the patients. The IFI titres were negative in 31.54% of the patients, between 1/16 and 1/32 in 38.34% and between 1/64 and 1/1,024 in only 30.07% of cases. The T CD4+ lymphocyte count was less than 200 cells in 66.7% of the patients; 72% of imaging studies showed typical lesions, in association with other disorders in 38% of the cases (lymphomas, cryptococcosis, tuberculous meningoencephalitis and cytomegalovirus encephalitis). CONCLUSIONS:NTX in a patient with AIDS often presents in our setting with headache and fever, motor deficit and alterations of consciousness. The diagnosis should be confirmed by immunological or imaging studies since in this disease serology and CSF studies are less specific.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Hernández-González E,Zamora F,Barnés J,Bender JE,Rodríguez-Delgado F,Millán-Marcelo JCsubject
Has Abstractpub_date
2002-04-01 00:00:00pages
618-21issue
7eissn
0210-0010issn
1576-6578pii
rn2001434journal_volume
34pub_type
杂志文章abstract:INTRODUCTION:Recent studies suggest that furosemide (FUR), a chloride cotransporting antagonist, acts directly on neurons of central nervous system modifying the ionic flow. OBJECTIVE:The aim of the present study was to determine the extrarenal antiedema effect of FUR. MATERIAL AND METHODS:Male Sprague-Dawley rats we...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract:INTRODUCTION:Eosinophil infiltration of skeletal muscle is rare, but often no etiological factor can be identified and these are isolated eosinophilic myositis. They may be associated with parasite infections or drugs, or be features of rare systemic disorders of hypereosinophilia, such as the myalgia eosinophilia synd...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-11-16 00:00:00
abstract:OBJECTIVE:To observe the frequency of various psychiatric disorders (depressive disorders, anxiety state and paraphrenic-paranoid disorders). PATIENTS AND METHODS:This study includes the 'cases' of dementia detected in an epidemiological field study done door-to-door, double phased and including non-institutionalized ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::The term 'acute myelopathies'--referred to a spinal cord dysfunction--represent a heterogeneous group of disorders with distinct etiologies, clinical and radiologic features, and prognoses. The objective of this review is to discuss the non-traumatic acute myelopathies. Acute myelopathy can be due to several causes as...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2013-09-06 00:00:00
abstract::Parkinson's disease is a neurodegenerative disorder associated with aging characterized by a motor extrapiramidal alteration secondary to the progressive death of dopaminergic neurons of the substantia nigra pars compacta. The cause of this neuronal loss remains unknown but post mortem studies on brains of parkinsonia...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-03-16 00:00:00
abstract:INTRODUCTION:Brain creatine deficiencies are a group of inborn errors of metabolism recently recognized which are caused by arginine: glycine amidinotransferase (AGAT) deficiency, guanidinoacetate metiltransferase (GAMT) deficiency and defects in creatine transporter (CRTR). Although all of them are characterized by a ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-03-16 00:00:00
abstract:TITLE:Signo de la banda en la esclerosis lateral primaria. : ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:10.33588/rn.6901.2019079
更新日期:2019-07-01 00:00:00
abstract::X-linked adrenoleukodystrophy is the prototype of the disorders that involve a single peroxisomal protein, and it is by far the most common peroxisomal disorder. The gene that is defective in this disorder is a peroxisomal membrane protein involved, in an as yet undefined manner, in the degradation of very long chain ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:INTRODUCTION:There is wide evidence about dopaminergic and noradrenergic mechanisms in fronto-striatal circuits which are thought to be related with attention deficit hyperactivity disorder (ADHD) neurobiology. That dysfunction may explain core symptoms and part of executive deficits in cognitive functioning. Methylphe...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-05-16 00:00:00
abstract:INTRODUCTION:Duchenne/Becker muscular dystrophy (DMD/B) is one of the commonest myopathies, with an incidence of 1/3,500 male live births. It is characterized by the slow degeneration of muscle fibres, so that the patient has become an invalid by the age of 10 years, followed by death from respiratory or cardiac failur...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2002-02-01 00:00:00
abstract::We present the association of a distrophinopathy with a case of facioscupulohumeral dystrophy in two individuals belonging to the same family. The discrepancy in the seric creatinphosphokinase (CPK) of the two patients together with certain clinical data suggests the possibility that it is a question of two different ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:INTRODUCTION:A spinal cord injury implies the loss of or alteration to the gait pattern. Stimulating the pattern generating centres in the sublesional spinal cord determines the appearance of flexion and extension automatisms that are useful for gait training in patients with spinal cord injuries. These centres can be ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract:INTRODUCTION:Severe myoclonic epilepsy in infancy (SMEI), or Dravet s syndrome, is one of the most serious forms of epilepsy in infancy. In this study we analyse the clinical characteristics of the process. PATIENTS AND METHODS:The cases reported in the literature are surveyed, together with a personal casuistic, from...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:To evaluate, using transcranial Doppler, changes in parameters in patients with cerebral hematoma, as compared with controls, for detection of possible regional hypoperfusion. PATIENTS AND METHODS:We studied 24 patients with cerebral hematomas and 15 healthy volunteers. The volume of the hematoma and the hyp...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-07-16 00:00:00
abstract:OBJECTIVES:To evaluate the diagnostic efficacy of an intra-arterial electroencephalographic recording and determine which patients obtain most benefit from this technique, to compare the results obtained using other recording techniques and to establish a standard for recording. PATIENTS AND METHODS:We made 64 intra-a...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract:INTRODUCTION:The new antiepileptic drugs should also be evaluated outside clinical trials. OBJECTIVE:To study the efficacy of treatment with lamotrigine in everyday neuropaediatric clinical practice. PATIENTS AND METHODS:We made a longitudinal study of all patients treated with lamotrigine in a hospital outpatients d...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-07-16 00:00:00
abstract:AIM:To document reversible cognitive deterioration associated to high doses of zonisamide, using the Reliable Change Index to control practice effects derived from repetitive neuropsychological assessments. CASE REPORT:A 11 year-old boy with tuberous sclerosis complex and left frontal refractory epilepsy, evaluated wi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2015-01-16 00:00:00
abstract:INTRODUCTION:Glutaric aciduria type I is an autosomal recessive inborn error of metabolism that is due to a deficiency of the enzyme glutaryl-CoA dehydrogenase, which gives rise to an accumulation of glutaric and 3-hydroxyglutaric acids in biological fluids. Clinical features present as a sudden-onset severe neurologic...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2007-05-16 00:00:00
abstract::Treatment of stroke is effective when given straight away at the onset of symptoms. Our objective was to find what the present latent periods in the medical attention of stroke patients are. A study was made in 18 hospital neurology units. The time elapsed between onset of the stroke and being attended by a doctor in ...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1996-04-01 00:00:00
abstract::The aim of our study was to compare a group of over 70 year-old patients suffering from spontaneous intracerebral haemorrhage with a similarly affected group under 70 years of age. With this in mind we carried out a prospective study of all patients admitted to the Neurology Service at the Virgen de la Arrixaca Hospit...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract:INTRODUCTION:The motor control deficits after stroke affect the gait pattern. There is a significant variability between subjects. AIMS:To analyse, by using a capture motion system, the gait pattern in stroke patients with different levels of motor function, and to establish, despite the participants heterogeneity, wh...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2016-11-16 00:00:00
abstract:OBJECTIVE:To evaluate the treatment modalities used in children (ages 1-18 years) with cerebral infarction. BACKGROUND:[corrected] Cerebrovascular disease in children is more common than once suspected but its treatment has not been rigorously studied. MATERIAL AND METHODS:We reviewed all cases of cerebral infarction...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract:INTRODUCTION:The possibility of diagnosing carotid stenosis and carrying out surgery without arteriography has increased with the use of different diagnostic methods. The eco-Doppler has been shown to be a useful method, although it requires previous individualised validation. OBJECTIVE:We aim to validate our Vascular...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:INTRODUCTION:Optogenetic is an experimental technique that combines genetic engineering and optical physics procedures to mark specific neurons in the brain and activate them at will through rays of light of certain frequency. AIM:To explain, to readers not versed in genetics the history, the rationale and the present...
journal_title:Revista de neurologia
pub_type: 历史文章,杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract:INTRODUCTION:Head tremor, either as an isolated symptom or as part of a symptomatic complex, occurs in patients with different neurological diseases. Little research has been carried out to analyse the clinical features of this neurological symptom. AIM:To review the symptomatology, aetiology and therapeutics of brain...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract:INTRODUCTION:Hirayama disease is a rare children's muscular atrophy that affects young Asian males, with muscular atrophy usually in one of the upper limbs that progresses slowly and later stabilises. It is diagnosed by means of electromyographic/electroneurographic with conduction speed studies (EMG/ENG-CS) and by mag...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract:AIM:To review about novel aspects in the initial management of patients with spontaneous intracerebral hemorrhage (SICH) and to analyze a group of predictors with influence on the election of certain therapies and on the 30-day mortality. DEVELOPMENT:SICH often constitutes a critical illness. Thus, many SICH patients ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-03-16 00:00:00
abstract:INTRODUCTION:Essential thrombocythemia (ET) is a myelodysplastic syndrome that constitutes an infrequent cause of ischemic stroke. Few clinical reports have been published describing the clinical onset of ET in the form of a vascular accident. CASE REPORT:We describe four cases of patients with no known haematological...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract:INTRODUCTION:Primary prevention by prophylactic vaccination against the major cause of cervical cancer, the carcinogenic human papillomavirus (HPV) types 16 and 18, is now available worldwide. Postlicensure adverse neurological effects have been described. The studies realized after the license are descriptive and limi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-04-16 00:00:00
abstract:INTRODUCTION:Cerebrovascular accidents (CVA) are the third most common cause of death and are the main cause of permanent disability in the western world, where they also rank first as regards the loss of years of disability-adapted independent life. Ischaemic CVAs tend to present irreversible sequelae, which reduces t...
journal_title:Revista de neurologia
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2007-11-01 00:00:00