当前位置： SCI文献检索 > SPINAL CORD期刊下所有文献 > Characteristics of sleep apnea syndrome in tetraplegic patients.

Characteristics of sleep apnea syndrome in tetraplegic patients.

Abstract：

OBJECTIVE:To include a larger number of tetraplegics than in previous studies, in order to more reliably characterize the pathogenesis and predisposing factors of sleep apnea in tetraplegia. METHODS:Sleep breathing data and oxymetric values were investigated in 50 randomly selected tetraplegic patients and discussed in context with age, gender, BMI, neck circumference, type and height of lesion, time after injury, spirometric values and medication. A non-validated short questionnaire on daytime complaints was added. RESULTS:Thirty-one patients out of 50 had an RDI > or =15, defined as sleep disordered breathing (SDB); 24 of them combined with an apnea index of 5 or more, these cases were diagnosed as sleep apnea syndrome (SAS). SAS was apparent in 55% and 20% of the studied men and women, respectively. Regression analyses showed no significant correlation between RDI and lesion level, ASIA impairment scale or spirometric values. In contrast, a significant correlation between RDI and age, BMI, neck circumference and time after injury could be shown. Kruskal-Wallis test for dichotomous non-parametric factors, such as gender, cardiac medication and daytime complaints, showed significant differences with regard to RDI. In contrast to able-bodied people with SAS, daytime complaints were only present in tetraplegic patients with severe pathology (RDI>40). CONCLUSION:Incidence of SAS is high in tetraplegia, particularly in older male patients with large neck circumference, long standing spinal cord injury and under cardiac medication. As tetraplegics with RDI between 15 and 40 reported no daytime complaints and often have normal BMI, these tetraplegics are not clinically suspicious for SAS. The increased use of cardiac medication in tetraplegics with SAS may implicate a link between SAS and cardiovascular morbidity, one of the leading causes of death in tetraplegia.

journal_name

Spinal Cord

journal_title

Spinal cord

authors

Stockhammer E,Tobon A,Michel F,Eser P,Scheuler W,Bauer W,Baumberger M,Müller W,Kakebeeke TH,Knecht H,Zäch GA

doi

10.1038/sj.sc.3101301

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

286-94

issue

eissn

1362-4393

issn

1476-5624

journal_volume

pub_type

杂志文章

在线工具

Characteristics of sleep apnea syndrome in tetraplegic patients.