Abstract:
:In a randomised, double-blinded, two-centre trial we evaluated the effect of a microbiological filter (Supor, Pall Life Sciences) on propofol injection pain. We studied 336 unpremedicated adult patients, who graded pain experienced during induction of anaesthesia with propofol on a 4-point verbal rating scale. Use of the microfilter reduced both the incidence and severity of propofol injection pain (p < 0.001). Incidence of severe pain in the filter group was 2.4% compared with 16.6% in the control group. Overall, 33.7% in the filter group experienced pain compared with 62.1% in the control group. A microbiological filter may provide a non-pharmacological alternative to a lidocaine/propofol mixture for reducing injection pain. It would also reduce the risk of any glass and bacterial contamination.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Davies AF,Vadodaria B,Hopwood B,Dexter T,Conn Ddoi
10.1046/j.1365-2044.2002.02602.xsubject
Has Abstractpub_date
2002-06-01 00:00:00pages
557-61issue
6eissn
0003-2409issn
1365-2044pii
2602journal_volume
57pub_type
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