Efficacy of microfiltration in decreasing propofol-induced pain.

Abstract:

:In a randomised, double-blinded, two-centre trial we evaluated the effect of a microbiological filter (Supor, Pall Life Sciences) on propofol injection pain. We studied 336 unpremedicated adult patients, who graded pain experienced during induction of anaesthesia with propofol on a 4-point verbal rating scale. Use of the microfilter reduced both the incidence and severity of propofol injection pain (p < 0.001). Incidence of severe pain in the filter group was 2.4% compared with 16.6% in the control group. Overall, 33.7% in the filter group experienced pain compared with 62.1% in the control group. A microbiological filter may provide a non-pharmacological alternative to a lidocaine/propofol mixture for reducing injection pain. It would also reduce the risk of any glass and bacterial contamination.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Davies AF,Vadodaria B,Hopwood B,Dexter T,Conn D

doi

10.1046/j.1365-2044.2002.02602.x

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

557-61

issue

6

eissn

0003-2409

issn

1365-2044

pii

2602

journal_volume

57

pub_type

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