Influence of ketanserin pretreatment on the haemodynamic responses to sternotomy.

Abstract:

:The effect of intravenous ketanserin on the pressor response to sternotomy was studied in 36 patients undergoing coronary artery surgery. Two doses of the drug (10 mg and 20 mg) were compared with a placebo injection of saline. After induction of anaesthesia, haemodynamic variables were measured until the institution of cardiopulmonary bypass. Plasma and platelet 5-hydroxyindoles and 5-hydroxytryptamine were measured in a subset of 13 patients. Ketanserin induced a dose-dependent amelioration of the pressor response to sternotomy. Plasma 5-hydroxyindoles and platelet 5-hydroxytryptamine levels did not correlate with clinical response. The increased effectiveness of the higher dose of ketanserin may be due to an effect other than serotonin antagonism.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Cashman JN,Thompson MA,Bennett A

doi

10.1111/j.1365-2044.1986.tb13275.x

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

505-10

issue

5

eissn

0003-2409

issn

1365-2044

journal_volume

41

pub_type

临床试验,杂志文章,随机对照试验
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    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1993.tb07529.x

    authors: Norman J

    更新日期:1993-12-01 00:00:00

  • Prolonged bradycardia and hypotension after neostigmine administration in a patient receiving atenolol.

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    doi:10.1111/j.1365-2044.1987.tb05277.x

    authors: Eldor J,Hoffman B,Davidson JT

    更新日期:1987-12-01 00:00:00

  • Use of the fibreoptic intubating LMA-CTrach in two patients with difficult airways.

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    authors: Goldman AJ,Rosenblatt WH

    更新日期:2006-06-01 00:00:00

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    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2010.06307.x

    authors: McElwain J,Malik MA,Harte BH,Flynn NM,Laffey JG

    更新日期:2010-05-01 00:00:00

  • AIDS in ICUs: outcome.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1988.tb05487.x

    authors: Deam R,Kimberley AP,Anderson M,Soni N

    更新日期:1988-02-01 00:00:00

  • alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role.

    abstract::Clonidine has proved to be a clinically useful adjunct in clinical anaesthetic practice as well as in chronic pain therapy because it has both anaesthetic and analgesic-sparing activity. The more selective alpha-2 adrenoceptor agonists, dexmedetomidine and mivazerol, may also have a role in providing haemodynamic stab...

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    pub_type: 杂志文章,评审

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    authors: Khan ZP,Ferguson CN,Jones RM

    更新日期:1999-02-01 00:00:00

  • Recovery times and side effects after propofol infusion and after isoflurane during ear surgery with additional infiltration anaesthesia.

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    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1988.tb09083.x

    authors: Ledderose H,Rester P,Carlsson P,Peter K

    更新日期:1988-03-01 00:00:00

  • A national survey of obstetric early warning systems in the United Kingdom: five years on.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.12708

    authors: Isaacs RA,Wee MY,Bick DE,Beake S,Sheppard ZA,Thomas S,Hundley V,Smith GB,van Teijlingen E,Thomas PW,Members of the Modified Obstetric Early Warning Systems Research Group.

    更新日期:2014-07-01 00:00:00

  • A survey of acute pain services in the UK.

    abstract::The organisational state of inpatient pain management in UK hospitals is difficult to determine. We sent an electronic questionnaire to 209 acute pain service leads throughout the UK. Questions were about staffing and service provision. We received 141 responses (67%); 47% of all UK hospitals. Each service was respons...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14007

    authors: Rockett M,Vanstone R,Chand J,Waeland D

    更新日期:2017-10-01 00:00:00

  • Severe hypotension due to intramyometrial injection of prostaglandin E2.

    abstract::Treatment of postpartum haemorrhage because of uterine atony with intramyometrial prostaglandin E2 1 mg, in an anaesthetised patient resulted in life-threatening hypotension. Anaesthetists should be aware of the potential cardiovascular side effects of prostaglandins. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1990.tb14569.x

    authors: Kilpatrick AW,Thorburn J

    更新日期:1990-10-01 00:00:00

  • Efficacy of sugammadex in rocuronium-induced or antibiotic-induced anaphylaxis. A case-control study.

    abstract::We report 13 cases of presumed rocuronium-induced anaphylaxis in which sugammadex was administered with the intention of reversing the immunological reaction. Of these 13 cases, eight (62%) were later confirmed to be type-1 hypersensitivity reactions to rocuronium, three (23%) were triggered by an antibiotic and two (...

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    pub_type: 杂志文章

    doi:10.1111/anae.13178

    authors: Platt PR,Clarke RC,Johnson GH,Sadleir PH

    更新日期:2015-11-01 00:00:00

  • Spinal anaesthesia for outpatient surgery.

    abstract::In a prospective study of 51 young male outpatients given spinal anaesthesia through a 25-gauge needle, we found a 37.2% incidence of postdural puncture headache. In addition, 54.9% complained of backache after surgery. Occurrence of headache significantly prolonged the sick-leave from work. General anaesthesia would ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1985.tb10612.x

    authors: Flaatten H,Raeder J

    更新日期:1985-11-01 00:00:00

  • A new method of predicting pulmonary capillary wedge pressure: the arterial pressure ratio.

    abstract::The response of arterial blood pressure to an increase in intrathoracic pressure has been shown to be predictive of pulmonary capillary wedge pressure. We devised a new method, which we termed the arterial pressure ratio. We defined arterial pressure ratio as the ratio of systolic blood pressure of the final beat duri...

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    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2000.055002113.x

    authors: Uehara H,Takenaka I,Aoyama K,Kadoya T,Sata T,Shigematsu A

    更新日期:2000-02-01 00:00:00

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13275

    authors: King W,Teare J,Vandrevala T,Cartwright S,Mohammed KB,Patel B

    更新日期:2016-02-01 00:00:00

  • Comparison of conventional intermittent positive pressure ventilation with high frequency jet ventilation. Studies following aortocoronary bypass graft surgery.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb04105.x

    authors: Normandale J,Patrick M,Sherry KM,Feneck RO

    更新日期:1987-08-01 00:00:00

  • The morphine sparing effects of diclofenac sodium following abdominal surgery.

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    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1987.tb05377.x

    authors: Hodsman NB,Burns J,Blyth A,Kenny GN,McArdle CS,Rotman H

    更新日期:1987-09-01 00:00:00

  • A comparison of patient and anaesthetist controlled midazolam sedation for dental surgery.

    abstract::Thirty healthy Hong Kong Chinese patients between the ages of 15 and 31 years with bilaterally impacted lower third molar teeth, scheduled for surgical removal were studied. All the patients presented twice (for the right and left sides) and received, on separate occasions, patient or anaesthetist-controlled midazolam...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb03431.x

    authors: Rodrigo MR,Tong CK

    更新日期:1994-03-01 00:00:00

  • Reversal of pancuronium with edrophonium.

    abstract::Edrophonium was administered as a bolus of 2, 10 or 50 mg (0.03, 0.14 and 0.71 mg/kg) to antagonize neuromuscular block after pancuronium in man. Neuromuscular transmission was measured using "train-of-four" stimulation. Recovery started within 1 min, was maximum at 2 min and was then followed by a plateau of slow con...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1979.tb06359.x

    authors: Bevan DR

    更新日期:1979-07-01 00:00:00

  • Effect of different surgical positions on the cerebral venous drainage: a pilot study using healthy volunteers.

    abstract::Excessive neck flexion and rotation in certain surgical positions may cause kinking of the internal jugular vein that obstructs cerebral venous blood flow and results in elevated intracranial pressure. The objective of this study was to measure internal jugular vein flow and identify potential impediments to venous fl...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13494

    authors: Yeoh TY,Tan A,Manninen P,Chan VW,Venkatraghavan L

    更新日期:2016-07-01 00:00:00

  • A comparison of the clinical use of the Laryngeal Tube S and the ProSeal Laryngeal Mask Airway by first-month anaesthesia residents in anaesthetised patients.

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    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2007.05073.x

    authors: Klaver NS,Kuizenga K,Ballast A,Fidler V

    更新日期:2007-07-01 00:00:00

  • Target ranges and the apparent compliance with tight glycaemic control.

    abstract::We performed a retrospective audit of blood glucose control after introducing a new protocol for insulin infusion. The audit showed a sustained reduction in the median blood glucose, which decreased from 7.0 to 6.8 mmol x l(-1), primarily because of a reduction in the proportion of values above 6 mmol x l(-1). When we...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2006.04817.x

    authors: Bone EG,Young D,Chantler J

    更新日期:2006-10-01 00:00:00

  • Pre-oxygenation and apnoea in pregnancy: changes during labour and with obstetric morbidity in a computational simulation.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2008.05785.x

    authors: McClelland SH,Bogod DG,Hardman JG

    更新日期:2009-04-01 00:00:00

  • The respiratory depressant effects of nalbuphine and papaveretum as intramuscular premedication.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb05223.x

    authors: Rutter GG,Aveling W,Tusiewicz K

    更新日期:1987-11-01 00:00:00

  • Optimisation of the organ donor and effects on transplanted organs: a narrative review on current practice and future directions.

    abstract::Mortality remains high for patients on the waiting list for organ transplantation. A marked imbalance between the number of available organs and recipients that need to be transplanted persists. Organs from deceased donors are often declined due to perceived and actual suboptimal quality. Adequate donor management off...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.15037

    authors: Bera KD,Shah A,English MR,Harvey D,Ploeg RJ

    更新日期:2020-09-01 00:00:00

  • Peri-operative administration of tranexamic acid in lower limb arthroplasty: a multicentre, prospective cohort study.

    abstract::In the UK, tranexamic acid is recommended for all surgical procedures where expected blood loss exceeds 500 ml. However, the optimal dose, route and timing of administration are not known. This study aimed to evaluate current practice of peri-operative tranexamic acid administration. Patients undergoing primary total ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1111/anae.15056

    authors: Lloyd TD,Neal-Smith G,Fennelly J,Claireaux H,Bretherton C,Carr AJ,Murphy M,Kendrick BJ,Palmer AJR,collaborators.

    更新日期:2020-08-01 00:00:00

  • Tracheal intubation following training with the GlideScope compared to direct laryngoscopy.

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    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2010.06335.x

    authors: Ayoub CM,Kanazi GE,Al Alami A,Rameh C,El-Khatib MF

    更新日期:2010-07-01 00:00:00

  • The Shikani optical stylet as an alternative to the GlideScope® videolaryngoscope in simulated difficult intubations--a randomised controlled trial.

    abstract::The GlideScope(®) videolaryngoscope is widely utilised in the management of the difficult airway. However, complications such as mucosal injury, palatal and tonsillar perforations have been reported with its use. The Shikani optical stylet has shown promise in aiding difficult intubations. This randomised controlled t...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2011.07023.x

    authors: Phua DS,Mah CL,Wang CF

    更新日期:2012-04-01 00:00:00

  • Oral ketamine. Its use for mentally retarded adults requiring day care dental treatment.

    abstract::Four cases of severely mentally handicapped young adults requiring day care dental treatment are reported. All had required varying degrees of restraint during previous dental treatments, which had been distressing for the patient, the relatives and the ward staff. In all cases, administration of oral ketamine 10 mg/k...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09713.x

    authors: Petros AJ

    更新日期:1991-08-01 00:00:00

  • Peribulbar anaesthesia using a mixture of local anaesthetic and vecuronium.

    abstract::The aim of this double-blind, randomised study was to assess the effects of the addition of 0.5 mg of vecuronium bromide to a standard local anaesthetic mixture used for peribulbar anaesthesia. We studied 60 patients undergoing regional anaesthesia for intra-ocular surgery and were primarily interested in the quality ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.1998.00433.x

    authors: Reah G,Bodenham AR,Braithwaite P,Esmond J,Menage MJ

    更新日期:1998-06-01 00:00:00

  • Aspiration in severe trauma: a prospective study.

    abstract::The incidence and origin of contamination of the vocal cords in 53 trauma patients was studied when tracheal intubation was performed before hospital admission. Eighteen patients (34%) had gross contamination which was blood in 15 patients and gastric contents in three patients. This has implications for prehospital a...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.1999.00754.x

    authors: Lockey DJ,Coats T,Parr MJ

    更新日期:1999-11-01 00:00:00