Inflammatory pseudotumor (myofibroblastic tumor) of the heart.


:Inflammatory pseudotumor (IPT) (also known as inflammatory myofibroblastic tumor) is an uncommon spindle cell lesion that was initially recognized in the lung and is now known to occur in virtually every major organ of the body. Its precise biological nature and clinical characteristics are still relatively uncertain. We report the case of a 7-month-old girl who was found to have an IPT of the right atrium. The rarity of IPT in the heart poses a diagnostic difficulty for both pediatricians and pathologists because of the clinical and morphologic overlap with other intracardiac masses in children. The differential diagnostic aspects of IPT of the heart are discussed and the literature on that lesion is reviewed.


Ann Diagn Pathol


Li L,Cerilli LA,Wick MR




Has Abstract


2002-04-01 00:00:00














  • Melanocytic "ball-in-mitts" and "microalveolar structures" and their role in the development of cellular blue nevi.

    abstract::To test the hypothesis of whether cellular blue nevi (CBN) may originate from "ordinary" compound and dermal nevi, a total of 275 melanocytic nevi including 59 CBN, 34 ordinary blue nevi, 87 combined nevi (including 43 so-called clonal nevi), 35 deep penetrating nevi, and 60 ordinary compound and dermal nevi (30 of ea...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Kazakov DV,Michal M

    更新日期:2007-06-01 00:00:00

  • Anaplastic large cell lymphoma: another entity in the differential diagnosis of small round blue cell tumors.

    abstract::We saw in consultation a biopsy specimen from a 6-year old girl with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL). The tumor arose in soft tissue of the neck, and diagnostic tissue was obtained by core needle biopsy. Histologically, the neoplasm was cellular without pattern. Immunohi...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Gustafson S,Medeiros LJ,Kalhor N,Bueso-Ramos CE

    更新日期:2009-12-01 00:00:00

  • Surgical pathology of granulomatous interstitial pneumonia.

    abstract::Agranulomatous interstitial pneumonia is a form of diffuse lung disease in which granulomas are a component of the histologic findings. The differential diagnosis is quite broad, but most cases represent examples of either sarcoidosis, diffuse granulomatous infections, or hypersensitivity pneumonitis. "Hot tub lung" i...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Cheung OY,Muhm JR,Helmers RA,Aubry MC,Tazelaar HD,Khoor A,Leslie KO,Colby TV

    更新日期:2003-04-01 00:00:00

  • Small cell osteosarcoma with Ewing sarcoma breakpoint region 1 gene rearrangement detected by interphase fluorescence in situ hybridization.

    abstract::Because of its characteristic morphologic appearance, small cell osteosarcoma (SCO) can be confused with other small round cell malignancies of the bone, most importantly with Ewing sarcoma, making this distinction difficult. A specific tool used in separating SCO from Ewing sarcoma has been the detection of Ewing sar...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Dragoescu E,Jackson-Cook C,Domson G,Massey D,Foster WC

    更新日期:2013-08-01 00:00:00

  • Parosteal lipoma of the thigh with cartilaginous and osseous differentiation: an osteochondrolipoma.

    abstract::Lipomas are very common benign soft tissue neoplasms. They are usually slow-growing and may occur anywhere in the body. Mature cartilage and bone arising in a lipoma is a rare event and is mostly associated with a parosteal localization of the neoplasm. We describe a new case of osteochondrolipoma showing not only maj...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Rau T,Soeder S,Olk A,Aigner T

    更新日期:2006-10-01 00:00:00

  • The surgical and cytopathology of viral infections: utility of immunohistochemistry, in situ hybridization, and in situ polymerase chain reaction amplification.

    abstract::The diagnosis of viral infections is an important part of the daily work of a surgical and cytopathologist. Some viral infections, such as human papillomavirus infection of the lower genital tract, are seen commonly, whereas others, such as fatal enteroviral infection, cannot be diagnosed on routine histological exami...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Nuovo GJ

    更新日期:2006-04-01 00:00:00

  • Hepatocellular carcinoma, syncytial giant cell: a novel variant in children: a case report.

    abstract::Hepatocellular carcinoma (HCC) is the second most common primary malignant hepatic tumor in children. It often develops in patients with underlying liver disease. We report the clinicopathologic features of an unusual HCC occurring in an infant who presented with features of Cushing's syndrome due to bilateral adrenal...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Atra A,Al-Asiri R,Wali S,Al-Husseini H,Al-Bassas A,Zimmermann A

    更新日期:2007-02-01 00:00:00

  • Sclerosing extramedullary hematopoietic tumor.

    abstract::A 73-year-old woman presented with abdominal pain, weakness, and weight loss. Pertinent medical history included myelofibrosis, severe anemia, and lumpectomy for breast cancer. Computed tomography showed marked splenomegaly and numerous soft tissue masses in the mesentery. Excisional biopsy of the mass showed an encap...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Yang X,Bhuiya T,Esposito M

    更新日期:2002-06-01 00:00:00

  • Processing the entire capsule in thyroid follicular lesions improves diagnostic accuracy.

    abstract:BACKGROUND:There is contradictory evidence in literature with respect to diagnosis and management of follicular lesions of the thyroid gland. From surgical pathology stand point, pathologists require submission and processing of entire capsule for microscopic evaluation. This can be extremely challenging especially in ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Hamza A,Khawar S,Alrajjal A,Salehi S

    更新日期:2019-04-01 00:00:00

  • Distribution of lymphoid neoplasms in Northwest China: Analysis of 3244 cases according to WHO classification in a single institution.

    abstract::To explore the distribution of lymphoid neoplasms in Northwest China, the clinical and pathological data of lymphoma patients from 2006 to 2014 were analyzed according to the WHO classification in Xijing Hospital. Of the 3244 cases, mature B-cell neoplasms occupied 60.7%, while mature T/NK-cell neoplasms and Hodgkin's...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Cao C,Feng J,Gu H,Tang H,Xu L,Dong H,Dong B,Shu M,Bai Q,Liang R,Zhang T,Yang L,Wang Z,Chen X,Gao G

    更新日期:2018-06-01 00:00:00

  • The Toker tumor: spectrum of morphologic features in primary neuroendocrine carcinomas of the skin (Merkel cell carcinoma).

    abstract::Primary neuroendocrine carcinoma of the skin is a relatively rare tumor that was first described by Cyril Toker in 1972. Since the seminal paper by Toker based on simple morphologic observations and detailed clinical correlation, our understanding of the clinical, morphological, and biological attributes of these lesi...

    journal_title:Annals of diagnostic pathology

    pub_type: 传,历史文章,杂志文章,评审


    authors: Plaza JA,Suster S

    更新日期:2006-12-01 00:00:00

  • The clinical use of a P63/cytokeratin7/18/cytokeratin5/14 antibody cocktail in diagnostic breast pathology.

    abstract::An antibody cocktail directed against p63, cytokeratin (CK)5/14, and CK7/18 is reported to be useful in distinguishing noninvasive from invasive breast lesions and for the characterization of intraductal epithelial proliferations. However, limited studies evaluate its use in clinical practice. A retrospective review o...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Reisenbichler ES,Ross JR,Hameed O

    更新日期:2014-12-01 00:00:00

  • Non-small cell lung carcinomas with CTNNB1 (beta-catenin) mutations: A clinicopathological study of 26 cases.

    abstract::Beta-catenin, encoded by the CTNNB1 gene, plays an important role in cell proliferation. Mutations of CTNNB1 are oncogenic in several tumor types and are often associated with a nuclear abnormal expression. However, such mutations have only rarely been reported in non-small cell lung carcinomas and their clinical sign...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Thomas de Montpréville V,Lacroix L,Rouleau E,Mamodaly M,Leclerc J,Tutuianu L,Planchard D,Boulate D,Mercier O,Besse B,Fadel É,Ghigna MR

    更新日期:2020-06-01 00:00:00

  • Pseudosarcoma in Paget's disease of bone.

    abstract::The appearance of a sarcoma of bone is a well-recognized complication of Paget's disease. The most common type of such a sarcoma is osteosarcoma. Much less common are soft tissue lesions adjoining the pagetic bone that clinically and radiologically simulate sarcoma but histologically represent exaggerated periosteal b...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Lamovec J,Rener M,Spiler M

    更新日期:1999-04-01 00:00:00

  • Pleural body cavity-based lymphoma.

    abstract::We report a case of recurrent body cavity-based non-Hodgkin's lymphoma in a patient with advanced acquired immunodeficiency syndrome who presented with bilateral pleural effusions, without evidence of an associated tumor mass. The lymphoma cells were large and pleomorphic, lacking pan-T- and pan-B-cell markers, but ex...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Perez MT,Cabello-Inchausti B,Viamonte M Jr,Nixon D

    更新日期:1998-04-01 00:00:00

  • Immunoexpression of p53 in cutaneous and subcutaneous leiomyosarcomas.

    abstract::The diagnosis of malignancy in cutaneous and subcutaneous smooth muscle tumors is based on subtle criteria. Therefore, any ancillary technique useful in this differential diagnosis is always welcome. In this report, we study the immunoexpression of p53 in 19 malignant smooth muscle tumors of the skin (15 cutaneous lei...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Fernandez-Flores A,Monteagudo C

    更新日期:2016-10-01 00:00:00

  • Intraductal tubular neoplasms of the pancreas: an overview.

    abstract::Intraductal lesions of the pancreas are an uncommon but increasingly recognized group of entities mainly because of advances in imaging technology. In the past, precise categorization and understanding of true pancreatic intraduct neoplasms were hampered not only by their relative rarity but also because of the pletho...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Chelliah A,Kalimuthu S,Chetty R

    更新日期:2016-10-01 00:00:00

  • Pancreatic endocrine tumor coexistent with serous microcystic adenoma: report of a case and review of the literature.

    abstract::Serous cystadenomas of the pancreas have been classified as benign exocrine tumors. There have been rare cases of malignant behavior, and in exceptional cases, coexisting neoplasms have been reported. We report a case of a coexistent neuroendocrine tumor identified within a serous cystadenoma in a 78-year-old woman, w...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Alasio TM,Vine A,Sanchez MA,Dardik H

    更新日期:2005-08-01 00:00:00

  • Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center.

    abstract::A granular cell tumor (GCT) is relatively uncommon and objectively diagnosed with neural markers on immunohistochemistry (IHC). Recent studies have described additional markers for a GCT. Herein, we present morphologic spectrum of 12 GCTs of soft tissues and skin, including 10 benign and 2 malignant subtypes with an o...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Rekhi B,Jambhekar NA

    更新日期:2010-06-01 00:00:00

  • Clinicopathologic and biomarker analysis of invasive pleomorphic lobular carcinoma as compared with invasive classic lobular carcinoma: an experience in our institution and review of the literature.

    abstract::Pleomorphic lobular carcinoma (PLC) is a distinct morphological variant of invasive lobular carcinoma (ILC). Although PLC retains the distinctive loosely cohesive and single-file growth pattern of ILC, it has specific distinguishable characteristics, including enlarged nuclei with greater nuclear irregularity, increas...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Jacobs M,Fan F,Tawfik O

    更新日期:2012-06-01 00:00:00

  • A uterine leiomyosarcoma that became positive for HMB45 in the metastasis.

    abstract::Uterine smooth muscle tumors are usually spindle cell lesions, but a minority is composed of epithelioid cells. Foci of clear cells can be found in these latter tumors. Recently, it has been shown that some of these tumors can be positive for HMB45, and some authors have advocated calling these lesions perivascular ep...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Silva EG,Bodurka DC,Scouros MA,Ayala A

    更新日期:2005-02-01 00:00:00

  • How much formalin is enough to fix tissues?

    abstract::A total of sixty samples from human breast, uterus, liver, skin and abdominal fat were fixed for 8; 24 and 48 hours at a room temperature of 20 to 22°C with neutral buffered formalin (NBF) with volume to tissue ratios of 1:1; 2:1; 5:1 and 10:1 and manually processed with isopropyl alcohol and mineral oil mixtures. All...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Buesa RJ,Peshkov MV

    更新日期:2012-06-01 00:00:00

  • Immunohistochemical expression of p16 protein in oral squamous cell carcinoma and lichen planus.

    abstract::Epithelial carcinogenesis is a multistep process. Specific genetic events lead to malignant transformation of oral epithelium. Oral squamous cell carcinoma (OSCC) may be preceded by potentially malignant lesions such as oral lichen planus (OLP). The p16 protein functions as a negative regulator of the cell cycle progr...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Salehinejad J,Sharifi N,Amirchaghmaghi M,Ghazi N,Shakeri MT,Ghazi A

    更新日期:2014-08-01 00:00:00

  • Osteoclastlike giant cell tumor of the salivary gland.

    abstract::Giant cell tumor of the salivary gland is extremely rare, with only 15 cases published in the English literature. The tumor characteristically contains a mixture of multinucleated giant cells, resembling osteoclasts of bone, and neoplastic mononuclear cells. In about half of the reported cases, there is an associated ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Fang X,Hicks DG,Hicks W Jr,Zhang S

    更新日期:2009-04-01 00:00:00

  • Breast metastasis by medullary thyroid carcinoma detected by FDG positron emission tomography.

    abstract::Medullary thyroid carcinoma (MTC) is an uncommon thyroid cancer comprising 5% to 8% of thyroid neoplasms. In contrast to common thyroid tumors, this tumor originates from the calcitonin-producing C cells. Regional metastases to cervical lymph nodes occur early in the disease, whereas distant metastasis occurs late. Co...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Nofech-Mozes S,Mackenzie R,Kahn HJ,Ehrlich L,Raphael SJ

    更新日期:2008-02-01 00:00:00

  • FTO mRNA expression in the lower quartile is associated with bad prognosis in clear cell renal cell carcinoma based on TCGA data mining.

    abstract::Fat mass and obesity associated (FTO) is a protein-coding gene, also known as the obesity gene. It has been reported previously to be associated with a variety of malignant cancers, such as breast, thyroid and acute myeloid leukemia. The aim of the present study was to investigate the FTO mRNA expression in human clea...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Wen L,Yu Y,Lv H,He Y,Yang B

    更新日期:2019-02-01 00:00:00

  • Clear cell renal cell carcinoma with focal renal angiomyoadenomatous tumor-like area.

    abstract::Recently, renal angiomyoadenomatous tumor (RAT) has been identified. However, there are no descriptions about clear cell renal cell carcinoma (RCC) with focal RAT-like features. A 33-year-old Japanese man was found to have a tumor in the left kidney. Macroscopically, the tumor extended into the perinephric fat tissue,...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Kuroda N,Hosokawa T,Michal M,Hes O,Sima R,Ohe C,Lee GH

    更新日期:2011-06-01 00:00:00

  • Cell turnover in apocrine metaplasia and apocrine adenosis of the breast.

    abstract::Apocrine metaplasia (APM) is a common finding in the breast of postmenopausal women and is seen in a broad spectrum of lesions ranging from microscopic cysts to invasive apocrine carcinoma. Apocrine metaplasia within sclerosing adenosis is known as apocrine adenosis (AA) and is considered a benign lesion of the breast...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Elayat G,Selim AG,Wells CA

    更新日期:2010-02-01 00:00:00

  • Expression of p27 and c-Myc by immunohistochemistry in breast ductal cancers in African American women.

    abstract:OBJECTIVES:Proteins p27 and c-Myc are both key players in the cell cycle. While p27, a tumor suppressor, inhibits progression from G1 to S phase, c-Myc, a proto-oncogene, plays a key role in cell cycle regulation and apoptosis. The objective of our study was to determine the association between expression of c-Myc and ...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Khan F,Ricks-Santi LJ,Zafar R,Kanaan Y,Naab T

    更新日期:2018-06-01 00:00:00

  • The cribriform features of adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma: cytokeratin and integrin expression.

    abstract::Cribriform areas are common features of both adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma. Both are malignant salivary gland tumors that share similar histologic patterns, but with marked distinct clinical behavior. This study was undertaken to improve the accuracy of the histopathology diagnosti...

    journal_title:Annals of diagnostic pathology

    pub_type: 杂志文章


    authors: Araújo VC,Loducca SV,Sousa SO,Williams DM,Araújo NS

    更新日期:2001-12-01 00:00:00