[Simultaneous radiochemotherapy in rectal tumors].

Abstract:

:After about 30 years from the first trials on concurrent chemoradiation in the treatment of rectal carcinoma, a large experience in this field has been shared, both in terms of laboratory and clinical data. The possibility of concurrent chemoradiation to improve the clinical outcome and sphincter preservation in low rectal tumors has been extensively demonstrated. Great attention should be paid to the quality of radiation treatment and drug administration, to minimize the risk of therapy-related toxicity. The impact of preoperative chemoradiation on tumor control will be further clarified by the ongoing randomized studies, in terms of comparison with radiation therapy alone (EORTC study), "Total mesorectal excision" (Duch Study), postoperative chemoradiation (German CAO/ARO/AIO 94) and the potential role of adjuvant chemotherapy (EORTC and Italian study). A series of phase II studies will probably clarify the role of unconventional fractionation modalities (hyperfractionation, accelerated treatments) and of new concomitant chemotherapy (new drugs, chronomodulation) in terms of organ and sphincter preservation. A close cooperation between radiation oncologists, medical oncologists and surgeons is required.

journal_name

Ann Ital Chir

authors

Valentini V,Valvo F,Cellini N

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

557-66

issue

5

eissn

0003-469X

issn

2239-253X

journal_volume

72

pub_type

杂志文章,评审
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    authors: Colonna MR,Baruffaldi Preis FW,Ponzielli G,Cavallini M,Giovannini UM,Di Leo A

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    authors: Moneghini D,Mittempergher F,Terraroli C,Di Fabio F

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    authors: Cartanese C,Minardi M,Crocco A,Barile G,De Luca R,Lomonaco R,Rucci A,Ruggieri E,Simone M

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    authors: Giordano G,Amoruso M,Angrisano A,Margari A

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,随机对照试验

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    authors: Chiaretti M,Fegatelli DA,Ceccarelli G,Carru GA,Pappalardo G,Chiaretti AI

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    authors: Atakul T,Tayyar AT,Küçük M,Turan ÖD,Özdemir E,Zafer E,Yüksel H

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Pagano G

    更新日期:2007-03-01 00:00:00

  • [Squamous carcinoma of the anal canal and its variations. Personal experience and review of the literature].

    abstract::Six cases of anal canal squamous carcinoma are presented. The authors precise the present view about pathological, epidemiological, clinical and therapeutical aspects of these lesions. They stress, also, the primary role of embryology and anatomy in the oncogenesis of such tumours; the importance to single out specifi...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Messinetti S,Marzullo A,Giacomelli L,Manno A,Pavone MG,Fabrizio G,Finizio R,Porcelli C,Granai AV

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  • The role of radiotherapy in the carotid stenosis.

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Simonetti G,Pampana E,Di Poce I,Orsini A,Pugliese F,Izzo S,Basso L,Nicolanti V,Al Mansour M,Di Cello P,Izzo L

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  • [Abdominal rectopexy in the treatment of rectal prolapse: how to foresee the functional result].

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Delaini GG,Scaglia M,Hulten L

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  • Poland syndrome: an algorithm to select the appropriate chest wall surgical reconstructive treatment.

    abstract:AIM:Poland syndrome is a constellation of rare congenital anomalies of the chest wall, with or without alterations to the ipsilateral superior extremity. Actually Foucras' classification is commonly used to choose the most appropriate surgical treatment, but often only a radiological classification proves unsatisfactor...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Chiummariello S,Pica A,Guarro G,Arleo S,Alfano C

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  • Natural history of hepatocellular carcinoma.

    abstract::Hepatocellular carcinoma (HCC) is a slowly growing tumor, whose natural history is not completely known. Since the hepatocarcinogenetic process may evolve for years in a stepwise fashion from premalignant to overt HCC, detection of early, better treatable tumors is made possible by surveillance of patients at risk. A ...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Colombo M

    更新日期:2008-03-01 00:00:00

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Cesaretti M,Ansaldo G,Varaldo E,Assalino M,Trotta M,Torre G,Borgonovo G

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  • [The surgery of lung metastases of melanoma].

    abstract::Melanoma is considered one of the most lethal cancers and surgical therapy of its pulmonary metastases is rarely indicated. The only hope for a successful surgical treatment of secondaries from melanoma is a radical resection. Considering the very frequent multiorgan involvement of melanoma metastases, surgery is usua...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Morone G,Meriggi F,Forni E

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  • A dissection of a manometric trace of the upper esophageal sphincter and the crico-esophageal coordination.

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Migliore M

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  • Infections of the aorta and iliac arteries. Report of 20 years experience in a single centre.

    abstract:AIM:Retrospective review of aorto-iliac infections in a single vascular surgery center. METHODS:From a retrospective review of their experience in the last 20 years, the Authors analyze a series of 12 cases of aorto-iliac infection. Prognostic factors, surgical options and results are discussed and compared with the l...

    journal_title:Annali italiani di chirurgia

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    doi:

    authors: Ferrante A,Cina A,Tsiopoulos VD,Snider F

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  • A common case with common problems: laparoscopic treatment of small bowel obstruction (SBO).

    abstract:BACKGROUND:Laparoscopic approach to patients with suspected small bowel obstruction (SBO) is not yet widely accepted nor clearly standardized; due to the absence of randomized trials, many questions still remain matter of debate. METHODS:By describing a single typical case of acute intestinal occlusive syndrome in a 8...

    journal_title:Annali italiani di chirurgia

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    doi:

    authors: Baiocchi GL,Vettoretto N,Zago M,Ansaloni L,Gheza F,Agresta F

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  • [A case of traditional appendectomy changed to laparoscopic surgery].

    abstract::The utility of appendectomy performed with laparoscopic procedure is at the present accepted by many surgeons, especially when there is uncertain diagnosis of appendicitis or when an ectopic position is suspected. The authors describe the case report of a 17 years old woman with a diagnosis of subacute appendicitis, i...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Cagnazzo A,Bianchi C,Varaldo E,Alitta P,Mattioli FP

    更新日期:1996-01-01 00:00:00

  • [Total gastrectomy for gastric neoplasms].

    abstract::In spite of the decreasing incidence of gastric carcinoma, as it is reported in recent reports from the U.S.A., total gastrectomy and its surgical indications results and complications, focus the interest of surgeons. We analize 61 cases of total gastrectomy for carcinoma, treated in the years 1982-1992. Perioperative...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Taschieri AM,Rovati MP,Elli M,Pisacreta M,Danelli PG,Lesma A,Cristaldi M,Tommaso V,Kurihara H

    更新日期:1995-11-01 00:00:00

  • [Treatment of traumatic lesions of the hepatic artery].

    abstract::Injuries to the porta hepatis, which are difficult to diagnose and require variable treatment, are rare. The mortality for the vascular injuries is directly correlated to the uncontrolled intraabdominal hemorrhage and the treatment requires primarily bleeding control. This paper reports a case of a laceration of the l...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Sica GS,Di Lorenzo N,Lania M,Ipri D,Magnacca F,Gaspari AL

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  • Fournier's gangrene. Immediate diagnosis and multimodality treatment is the comerstone for successful outcome.

    abstract:BACKGROUND:Fournier's gangrene is a synergistic necrotic fasciitis or myositis of genitalia, perineum and abdominal wall. Several etiologic factors have been reported, microorganisms isolated and co-morbidity factors identified. Immediate and accurate diagnosis decreases mortality rate, which ranges from 3-67%. Aggress...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Rizos S,Filippou DK,Condilis N,Filippou G,Trigka A,Skandalakis P,Vezakis A

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  • [Congenital dilatation of the biliary system in adult: about three clinical cases].

    abstract::The authors refer to three cases of congenital dilatation of the biliary system in an adult, an extremely rare pathology in the West, with no specific symptomatology, and therefore often discovered accidentally and unexpectedly The first patient had suffered from unexplained periods of fever since childhood, the secon...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Ungania S,Barletta N

    更新日期:2011-11-01 00:00:00

  • Large mediastinal nodular ganglioneuroblastoma in a child from Africa.

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Guarino S,Astini C,Howard JP,Colombelli V

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  • Coronary artery bypass grafting in the octogenarian. Is complete revascularization always necessary?

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Concistrè G,Dell'Aquila AM,Gallo A,Pansini S,Piccardo A,Rapetto F,Passerone G,Regesta T

    更新日期:2015-01-01 00:00:00

  • Modern surgical technique for thyroidectomy.

    abstract::Extracapsular lobectomy or total thyroidectomy are the surgical techniques normally used to deal with either benign or malignant thyroid diseases needing surgery. Both the well-known pathogenesis of benign surgical pathology and the positive role of post-operative radiometabolic treatment for differentiated carcinomas...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Picardi N

    更新日期:1998-01-01 00:00:00

  • [Methods of intraoperative localization in the surgery treatment of persistent and recurrent secondary hyperparathyroidism].

    abstract::The intraoperative localization of residual parathyroid tissue during re-operations for persistent or recurrent secondary hyperparathyroidism (HPT) could have difficult due to cicatricial phenomena, anatomic modifications, ectopic or super-numerous glands. The use of intraoperative localisatin methods, as ultrasonogra...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Casella C,di Fabio F,Pata G,Salerni B

    更新日期:2006-11-01 00:00:00

  • One stage curative resection of double intestinal neuroendocrine tumors with thirty-two bilobar liver metastases. A case report.

    abstract::Neuroendocrine tumours (NETs) of the midgut are often multifocal and have a noticeable attitude to metastasize to locoregional lymph nodes and liver. Surgery is the only curative treatment for metastatic NETs of the midgut, even though only a minority of patients are candidates to radical surgical resection. The optim...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Mirarchi M,De Raffele E,Cuicchi D,Lecce F,Cruciani G,Cola B

    更新日期:2015-07-01 00:00:00

  • Biliary papillomatosis. Case report.

    abstract::Biliary papillomatosis is a disease characterized by multiple papillary tumours of variable distribution and extent in the intrahepatic and/or extrahepatic biliary tree. Papillary carcinoma can develop within these lesions. Because biliary papillomatosis is a rare biliary pathological entity, its clinical features and...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Forlano I,Fersini A,Tartaglia N,Ambrosi A,Neri V

    更新日期:2011-09-01 00:00:00

  • [Inflammatory colitis: classification and surgical treatment].

    abstract::The development of clinical and histopathological criteria for the diagnosis of Crohn's disease (CD) and ulcerative colitis (UC), pushed the scientists to identify a new category: the indeterminate colitis (CI). This term is used when definitive diagnosis of UC or CD has not been made by colonoscopy, colonic biopsy or...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Baratti C,De Simone A,Grassi C,Righi I,Massara PP,Pizzi M,Ferla F,Sposato J,Ardizzone S,Trabucchi E

    更新日期:2006-07-01 00:00:00