Primary actinomycosis of the breast in postmenopausal women.

Abstract:

INTRODUCTION:Actinomycosis is a chronic infection caused by actinomyces species characterized by an abscess formation, tissue fibrosis, and draining sinuses. Primary actinomycosis of the breast is rare. PATIENTS AND METHODS:In this paper we present a 64-year-old postmenopausal woman. For the diagnosis of primary actinomycosis of the breast, mammography, ultrasonography, MRI, and histopathologic examinations are required. Microbiological culture and histopathology are of the most importance during the process of diagnosis. In our case, at the intersection of the sternum and the lower inner quadrant of the right breast, there was a 1 cm wide fistula opening, and an abscess. A. israelii has been isolated from the microbiological culture taken from the lesion RESULTS: An optimal surgical resection of infected tissues has been performed as the treatment with the wound left open for tertiary healing The patient was given sulbactam 4*1 gr/day intravenously for 4 weeks post-op.. Recurrence was not detected during the yearly follow up procedures CONCLUSIONS: Actinomycosis should be considered when differentially diagnosing clinical instances of suppurative or granulomatous infections of the breast and mass regions that can't be ruled out as malignancies. Early diagnosis will save the patient from unnecessary surgical operations and ineffective antibiotic treatments. KEY WORDS:Actinomycosis, Breast abscess, Breast diseases. :L’actinomicosi è un’infezione cronica causata da specie di actinomyces caratterizzata da formazione di ascessi, fibrosi tissutale e fistolizzazionr, di rara localizzazione al seno. Viene qui presentato il caso di una donna di 64 anni in postmenopausa. La diagnosi di actinomicosi primaria del seno sono ha richiesto esami mammografici, ecografici e con RM e controlli istopatologici. La coltura microbiologica e l’istopatologia sono della massima importanza durante il processo di diagnosi. Nel nostro caso, all’intersezione dello sterno e del quadrante interno inferiore del seno destro, c’era una fistola larga 1 cm e un ascesso. Dalla coltura microbiologica dall’essudato fistoloso è stato isolato Actinomyces israelii. È stata eseguita una resezione chirurgica ottimale dei tessuti infetti, lasciando la ferita aperta per una guarigione per terza intenzione. Per 4 settimane dopo l’intervento è stato somministrato Sulbactam per via endovenosa (1 gr x 4/die). Ad un anno non si riscontrata alcuna recidiva. In conclusione l’actinomicosi deve essere presa in considerazione nella diagnosi differenziata anche in caso di infezioni suppurative o granulomatose del seno e delle masse di tessuti che non possono essere esclusi per natura neoplastica. La diagnosi precoce salverà il paziente da interventi chirurgici inutilmente demolitivi e da trattamenti antibiotici inefficaci.

journal_name

Ann Ital Chir

authors

Yalav O,Topal U,Ünal AG,Dalci K

subject

Has Abstract

pub_date

2019-12-20 00:00:00

eissn

0003-469X

issn

2239-253X

pii

S2239253X19031232

journal_volume

8

pub_type

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