Large mediastinal nodular ganglioneuroblastoma in a child from Africa.

Abstract:

:Ganglioneuroblastoma, nodular (GNBn) is a subtype of neuroblastic tumors. This is a rare malignancy typically affecting young children. Few cases are reported in adolescents and adults. The prognosis is related to the surgical excision radicality. Hereby we present a case of a young male patient age 13 from the Horn of Africa presenting with vague symptoms of fatigue and weight loss. Chest X-ray showed a large radiopaque mass occupying the right thorax. The chest Computed Tomograpy confirmed the presence of an 18-cm large mass originating from the posterior mediastinum and invading most of the right hemi-thorax. Surgical excision and histopathology study of the lesion clarified its rare nature: ganglioneuroblastoma nodular with a particular coexistence of a fibrous benign surface encapsulating a necrotic malignant core. In this case of large GNBn in a young adolescent, the surgical resection alone played a curative treatment role.

journal_name

Ann Ital Chir

authors

Guarino S,Astini C,Howard JP,Colombelli V

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

543-6

issue

6

eissn

0003-469X

issn

2239-253X

pii

S0003469X12018477

journal_volume

83

pub_type

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