Immediate hypersensitivity to tuberculin. In vivo and in vitro studies.

Abstract:

:Immediate responses of hypersensitivity to skin testing with purified derivative of tuberculin (PPD) were observed in 2.3 percent of 3,248 patients seen in an allergy clinic, and the relationship to delayed responses was questioned. Immediate cutaneous reactions to testing with PPD appeared in all age groups and occurred in nonatopic patients but were more common in atopic patients (p less than 0.005). Delayed cutaneous reactions to testing with PPD occurred in only three out of 76 patients with immediate reactivity. Antihistaminic suppression of immediate reactivity was not followed by evidence of delayed cutaneous reactivity. In vitro tests of lymphocytic stimulation revealed indices of stimulation with PPD to be similar both in patients with immediate and delayed cutaneous reactivity. Failure to manifest delayed cutaneous reactivity following immediate cutaneous reactions alone may be explained by antigen-antibody binding and phagocytosis, by suppressor T-lymphocytes, or by impaired release or lack of response to T-lymphocytic mediators. Adverse reactions to administration of BCG vaccine in patients with immediate cutaneous reactivity might be anticipated.

journal_name

Chest

journal_title

Chest

authors

Tarlo SM,Day JH,Mann P,Day MP

doi

10.1378/chest.71.1.33

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

33-7

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)53117-6

journal_volume

71

pub_type

杂志文章

相关文献

CHEST文献大全
  • Clinical applications of targeted temperature management.

    abstract::Targeted temperature management (TTM) has been investigated experimentally and used clinically for over 100 years. The initial rationale for the clinical application of TTM, historically referred to as therapeutic hypothermia, was to decrease the metabolic rate, allowing the injured brain time to heal. Subsequent rese...

    journal_title:Chest

    pub_type: 历史文章,杂志文章,评审

    doi:10.1378/chest.12-3025

    authors: Perman SM,Goyal M,Neumar RW,Topjian AA,Gaieski DF

    更新日期:2014-02-01 00:00:00

  • Percutaneous balloon pericardiotomy for malignant pericardial tamponade.

    abstract::Recurrent pericardial effusion or tamponade can complicate malignant disease. The medical approach with pharmacologic agents has a high recurrence rate. Balloon pericardiotomy (BP) may provide a less invasive alternative to surgery. We performed BP in ten high-risk patients with malignant pericardial tamponade (MPT). ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.6.1499

    authors: Galli M,Politi A,Pedretti F,Castiglioni B,Zerboni S

    更新日期:1995-12-01 00:00:00

  • Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation.

    abstract:BACKGROUND:There is significant heterogeneity within the primary graft dysfunction (PGD) syndrome. We aimed to identify distinct grade 3 PGD phenotypes based on severity of lung dysfunction and patterns of resolution. METHODS:Subjects from the Lung Transplant Outcomes Group (LTOG) cohort study with grade 3 PGD within ...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.12-1480

    authors: Shah RJ,Diamond JM,Cantu E,Lee JC,Lederer DJ,Lama VN,Orens J,Weinacker A,Wilkes DS,Bhorade S,Wille KM,Ware LB,Palmer SM,Crespo M,Localio AR,Demissie E,Kawut SM,Bellamy SL,Christie JD

    更新日期:2013-08-01 00:00:00

  • Sensitivity and specificity of radioisotope right-left shunt measurements and pulse oximetry for the early detection of pulmonary arteriovenous malformations.

    abstract:STUDY OBJECTIVES:To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT). DESIGN:Patients with HHT had serial measurements of the followi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.1.109

    authors: Thompson RD,Jackson J,Peters AM,Doré CJ,Hughes JM

    更新日期:1999-01-01 00:00:00

  • Nutrition in the ICU: an evidence-based approach.

    abstract::Providing artificial nutrition is an important part of caring for critically ill patients. However, because of a paucity of robust data, the practice has been highly variable and often based more on dogma than evidence. A number of studies have been published investigating many different aspects of critical care nutri...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.13-1158

    authors: Desai SV,McClave SA,Rice TW

    更新日期:2014-05-01 00:00:00

  • Positional dyspnea and oxygen desaturation related to carcinoma of the lung. Up with the good lung.

    abstract::Body position can lead to respiratory symptoms and affect gas exchange in disease states. We describe a patient with carcinoma of the left lung in whom dyspnea and oxygen desaturation developed in the right lateral position only. Fiberoptic bronchoscopic study demonstrated a tumor mass protruding into the left main-st...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.83.5.826

    authors: Mahler DA,Snyder PE,Virgulto JA,Loke J

    更新日期:1983-05-01 00:00:00

  • Long-term effects of nitrendipine on hemodynamics and oxygen transport in patients with cor pulmonale.

    abstract::Recent studies have suggested that vasodilators may acutely improve pulmonary hemodynamics in patients with chronic obstructive pulmonary disease and cor pulmonale, but the effects of long-term therapy have not been assessed. We evaluated the hemodynamic and gas exchange effects of nitrendipine, a calcium channel bloc...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.1.141

    authors: Rubin LJ,Moser K

    更新日期:1986-01-01 00:00:00

  • Intrapleural recombinant IL-2 in passive immunotherapy for malignant pleural effusion.

    abstract::The purpose of this phase 1 study was to determine the toxicity and effectiveness of recombinant interleukin-2 (RU 49637 Roussel Uclaf-France) administered by continuous pleural infusion for 5 days to patients with different histologic subtypes of pleural cancer. Incremental doses of rIL-2 from 3 x 10(6) to 24 x 10(6)...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.103.1.209

    authors: Astoul P,Viallat JR,Laurent JC,Brandely M,Boutin C

    更新日期:1993-01-01 00:00:00

  • Subclinical cardiac dysfunction in sarcoidosis.

    abstract::Clinically apparent myocardial disease is infrequent in sarcoidosis. However, autopsy data show myocardial involvement in up to 30 percent of patients. Unexplained exertional symptomatology is a common complaint in patients with sarcoidosis. In this study, we investigated whether abnormal cardiac function might limit ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.1.44

    authors: Gibbons WJ,Levy RD,Nava S,Malcolm I,Marin JM,Tardif C,Magder S,Lisbona R,Cosio MG

    更新日期:1991-07-01 00:00:00

  • Greater risk of hospitalization in children with Down syndrome and OSA at higher elevation.

    abstract:BACKGROUND:Children with Down syndrome (DS) are at high risk for OSA. Increasing elevation is known to exacerbate underlying respiratory disorders and worsen sleep quality in people without DS, but whether altitude modulates the severity of OSA in DS is uncertain. In this study, we evaluate the impact of elevation (≤ 1...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.14-1883

    authors: Jensen KM,Sevick CJ,Seewald LAS,Halbower AC,Davis MM,McCabe ERB,Kempe A,Abman SH

    更新日期:2015-05-01 00:00:00

  • Comparison of arterial-end-tidal PCO2 difference and dead space/tidal volume ratio in respiratory failure.

    abstract::End-tidal CO2 monitors are used to estimate arterial CO2 pressure (PaCO2), but appropriate use of this noninvasive method of assessing blood gases is unclear. In patients with lung disease, the end-tidal CO2 pressure (PETCO2) can differ from PaCO2 because of ventilation-perfusion (VA/Q) mismatching, and changes in PET...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.5.832

    authors: Yamanaka MK,Sue DY

    更新日期:1987-11-01 00:00:00

  • International trends in asthma mortality rates in the 5- to 34-year age group: a call for closer surveillance.

    abstract:BACKGROUND:International time trends in asthma mortality have played an important sentinel role in the identification of two epidemics of asthma mortality in some countries in the 1960s and the 1970s and 1980s. Since then, little attention has been paid to the ongoing international time trends. METHODS:Country-specifi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-2082

    authors: Wijesinghe M,Weatherall M,Perrin K,Crane J,Beasley R

    更新日期:2009-04-01 00:00:00

  • Oral corticosteroids increase esophageal acid contact times in patients with stable asthma.

    abstract:STUDY OBJECTIVES:The prevalence of gastroesophageal reflux disease (GERD) is higher in people with asthma than in control populations. Predisposing factors for GERD development may include asthma medications such as prednisone. The objective of this study was to determine whether prednisone alters GERD parameters in pe...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.121.2.625

    authors: Lazenby JP,Guzzo MR,Harding SM,Patterson PE,Johnson LF,Bradley LA

    更新日期:2002-02-01 00:00:00

  • Relationship of resting lung mechanics and exercise pattern of breathing in patients with chronic obstructive lung disease.

    abstract::To investigate the influence of resting pulmonary mechanics on the pattern of breathing during exercise in chronic obstructive pulmonary disease (COPD), we studied 29 patients with moderate to severe COPD (FEV1 50 +/- 20 percent predicted), and 10 normal subjects. Lung mechanics were studied using esophageal balloon t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.3.705

    authors: Marin JM,Hussain SN,Gibbons WJ,Polverino M,Levy RD,Cosio MG

    更新日期:1993-09-01 00:00:00

  • Usefulness of bronchoscopic microsampling to detect the pathogenic bacteria of respiratory infection.

    abstract:BACKGROUND:Bronchoscopic microsampling (BMS) is a method in which a device consisting of a wire with a polyester probe at the tip is used to collect bronchial epithelial lining fluid with bronchoscopy. In this study, we bacteriologically investigated sample collection using BMS to incorporate BMS into diagnosis of resp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.06-0989

    authors: Sasabayashi M,Yamazaki Y,Tsushima K,Hatayama O,Okabe T

    更新日期:2007-02-01 00:00:00

  • Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features.

    abstract:BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.08.2115

    authors: Billatos E,Ash SY,Duan F,Xu K,Romanoff J,Marques H,Moses E,Han MK,Regan EA,Bowler RP,Mason SE,Doyle TJ,San José Estépar R,Rosas IO,Ross JC,Xiao X,Liu H,Liu G,Sukumar G,Wilkerson M,Dalgard C,Stevenson C,Whitney

    更新日期:2020-09-16 00:00:00

  • Prediction of postoperative pulmonary function with the lateral position test. A prospective study.

    abstract::Ten patients undergoing pneumonectomy were evaluated with the lateral position test (LPT) in addition to routine pulmonary function tests (PFTs). On the basis of the percentage of ventilation estimated to be contributed by each lung on LPT, predictions were made for expected values for each patient's post-pneumonectom...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.77.1.24

    authors: Walkup RH,Vossel LF,Griffin JP,Proctor RJ

    更新日期:1980-01-01 00:00:00

  • Biochemical response to treatment of bone hyperresorption in chronically critically ill patients.

    abstract:STUDY OBJECTIVE:The chronically critically ill (CCI) are a subgroup of critically ill patients who have survived an acute critical illness but remain profoundly debilitated and ventilator dependent. We have previously shown that CCI patients have a very high prevalence of bone hyperresorption. The objective of this pre...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.118.3.761

    authors: Nierman DM,Mechanick JI

    更新日期:2000-09-01 00:00:00

  • Clinical and Imaging Features of COVID-19 in a Neonate.

    abstract::We report the clinical history, laboratory findings, and imaging features of coronavirus disease 2019 (COVID-19) in a neonate whose mother was also a patient. The newborn was the youngest patient with COVID-19 in the world at the time he was diagnosed. This case has brought more attention and understanding to the epid...

    journal_title:Chest

    pub_type:

    doi:10.1016/j.chest.2020.03.018

    authors: Xiong Y,Zhang Q,Zhao L,Shao J,Zhu W

    更新日期:2020-07-01 00:00:00

  • Cocaine-induced bradyarrhythmia: an unsuspected cause of syncope.

    abstract::Cocaine use is associated with adverse events in nearly every organ system. Cardiovascular complications include hemorrhagic and ischemic stroke, aortic dissection, cardiomyopathy, accelerated coronary artery disease, myocardial infarction, and sudden cardiac death. Syncope may be the presenting symptom in these condi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.1.275

    authors: Castro VJ,Nacht R

    更新日期:2000-01-01 00:00:00

  • Decrease in mortality in severe community-acquired pneumococcal pneumonia: impact of improving antibiotic strategies (2000-2013).

    abstract:OBJECTIVE:The objective of the present study was to compare antibiotic prescribing practices and survival in the ICU for patients with pneumococcal severe community-acquired pneumonia (SCAP) between 2000 and 2013. METHODS:This was a matched case-control study of two prospectively recorded cohorts in Europe. Eighty pat...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.13-1531

    authors: Gattarello S,Borgatta B,Solé-Violán J,Vallés J,Vidaur L,Zaragoza R,Torres A,Rello J,Community-Acquired Pneumonia en la Unidad de Cuidados Intensivos II Study Investigators*.

    更新日期:2014-07-01 00:00:00

  • Dynamic expiratory tracheal collapse in COPD: correlation with clinical and physiologic parameters.

    abstract:BACKGROUND:COPD has been described as a risk factor for excessive expiratory tracheal collapse, but its prevalence and clinical correlates have not been fully determined. The purpose of this study is to prospectively determine the prevalence of excessive expiratory tracheal collapse among patients with COPD and to test...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-0299

    authors: Boiselle PM,Michaud G,Roberts DH,Loring SH,Womble HM,Millett ME,O'Donnell CR

    更新日期:2012-12-01 00:00:00

  • Multicentric endobronchial granular cell myoblastoma.

    abstract::Granular cell myoblastoma (GCM) is a rare benign neoplasm involving the tracheobronchial tree. It is believed to arise from the Schwann cell. Four cases of tracheobronchial GCM, all of which were multicentric, are presented and a conservative therapeutic approach is suggested. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.4.945

    authors: Redjaee B,Rohatgi PK,Herman MA

    更新日期:1990-10-01 00:00:00

  • Complementary therapies and integrative medicine in lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

    abstract:BACKGROUND:Physicians are often asked about complementary therapies by patients with cancer, and data show that the interest in and use of these therapies among patients with cancer is common. Therefore, it is important to assess the current evidence base on the benefits and risks of complementary therapies (modalities...

    journal_title:Chest

    pub_type: 杂志文章,实务指引

    doi:10.1378/chest.12-2364

    authors: Deng GE,Rausch SM,Jones LW,Gulati A,Kumar NB,Greenlee H,Pietanza MC,Cassileth BR

    更新日期:2013-05-01 00:00:00

  • Prognosis and recurrent patterns in bronchioloalveolar carcinoma.

    abstract:STUDY OBJECTIVE:Bronchioloalveolar carcinoma (BAC) is an uncommon pulmonary neoplasm with various radiologic and clinical presentations. In this article, we analyze the initial radiologic findings, TNM stagings, surgical types, and radiologic features of recurrence, and correlate them with patient survival. DESIGN:A r...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.118.4.940

    authors: Liu YY,Chen YM,Huang MH,Perng RP

    更新日期:2000-10-01 00:00:00

  • Evaluation of lung function during pulmonary rejection and infection in heart-lung transplant patients. Hannover Lung Transplant Group.

    abstract::Pulmonary rejection and infection are the most important complications after lung transplantation. To evaluate the diagnostic value of pulmonary function testing for early detection and discrimination of these complications, seven heart-lung recipients were examined. The diagnosis of each complication was confirmed by...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.3.864

    authors: Hoeper MM,Hamm M,Schäfers HJ,Haverich A,Wagner TO

    更新日期:1992-09-01 00:00:00

  • The significance of distal bronchial samples with commensals in ventilator-associated pneumonia: colonizer or pathogen?

    abstract:STUDY OBJECTIVE:To investigate the role of oropharyngeal and cutaneous commensal microorganisms (OCCs) as a cause of ventilator-associated pneumonia (VAP). DESIGN:Retrospective analysis of the medical and microbiological records. SETTING:One medical-surgical ICU. PATIENTS:All VAP episodes recorded during a 10-year p...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.4.1389

    authors: Lambotte O,Timsit JF,Garrouste-Orgeas M,Misset B,Benali A,Carlet J

    更新日期:2002-10-01 00:00:00

  • Solid or partly solid solitary pulmonary nodules: their characterization using contrast wash-in and morphologic features at helical CT.

    abstract:BACKGROUND:Solitary pulmonary nodule (SPN) evaluation based on analyses of combined wash-in (WI) and washout (WO) values obtained by helical dynamic CT (HDCT) scanning is useful for malignant SPN characterization, because this method has higher specificity and accuracy than that based on analyses of WI values only. How...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.06-2526

    authors: Lee KS,Yi CA,Jeong SY,Jeong YJ,Kim S,Chung MJ,Kim HY,Kim YK,Lee KH

    更新日期:2007-05-01 00:00:00

  • Diaphragm muscle thinning in patients who are mechanically ventilated.

    abstract:BACKGROUND:Approximately 40% of patients in medical ICUs require mechanical ventilation (MV). Approximately 20% to 25% of these patients will encounter difficulties in discontinuing MV. Multiple studies have suggested that MV has an unloading effect on the respiratory muscles that leads to diaphragmatic atrophy and dys...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-1638

    authors: Grosu HB,Lee YI,Lee J,Eden E,Eikermann M,Rose KM

    更新日期:2012-12-01 00:00:00

  • Determination of bronchodilation in the clinical pulmonary function laboratory. Role of changes in static lung volumes.

    abstract::Improved airway resistance following bronchodilator inhalation is not always accompanied by improvement in forced expiratory flow. We studied 241 patients with airways obstruction to learn whether changes in static lung volumes (vital capacity and function residual capacity measured by body plethysmography [FRCB]) wou...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.76.6.622

    authors: Ramsdell JW,Tisi GM

    更新日期:1979-12-01 00:00:00