Aging cognition: from neuromodulation to representation.

Abstract:

:Basic cognitive functions, such as the abilities to activate, represent, maintain, focus and process information, decline with age. A paradigm shift towards cross-level conceptions is needed in order to obtain an integrative understanding of cognitive aging phenomena that cuts across neural, information-processing, and behavioral levels. We review empirical data at these different levels, and computational theories proposed to enable their integration. A theoretical link is highlighted, relating deficient neuromodulation with noisy information processing, which might result in less distinctive cortical representations. These less distinctive representations might be implicated in working memory and attentional functions that underlie the behavioral manifestations of cognitive aging deficits.

journal_name

Trends Cogn Sci

authors

Li SC,Lindenberger U,Sikström S

doi

10.1016/s1364-6613(00)01769-1

subject

Has Abstract

pub_date

2001-11-01 00:00:00

pages

479-486

issue

11

eissn

1364-6613

issn

1879-307X

pii

S1364-6613(00)01769-1

journal_volume

5

pub_type

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